В. М. Акімова

ORCID: 0000-0003-2334-1273
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Diagnosis and treatment of tuberculosis
  • Atherosclerosis and Cardiovascular Diseases
  • Cardiovascular Disease and Adiposity
  • Tuberculosis Research and Epidemiology
  • Healthcare Systems and Public Health
  • Human Health and Disease
  • Medical and Biological Sciences
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cytokine Signaling Pathways and Interactions
  • Neurological Disorders and Treatments
  • Biomarkers in Disease Mechanisms
  • Retinal and Optic Conditions
  • Diet, Metabolism, and Disease
  • Pediatric health and respiratory diseases
  • Appendicitis Diagnosis and Management
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Therapeutic Uses of Natural Elements
  • Medical and Biological Ozone Research
  • Nutrition, Genetics, and Disease
  • Global Healthcare and Medical Tourism
  • GDF15 and Related Biomarkers
  • Carbohydrate Chemistry and Synthesis
  • Inflammation biomarkers and pathways
  • S100 Proteins and Annexins

Danylo Halytsky Lviv National Medical University
2018-2024

I.Horbachevsky Ternopil National Medical University
2018

The publication highlights the importance of standardizing urine analysis and prospects for implementing European recommendations developed by Federation Clinical Chemistry Laboratory Medicine in Ukraine. It describes key aspects adapting international standards to national laboratory practice, particularly implementation practice challenges that may arise this process.

10.62151/2786-9288.3.1.2025.01 article EN Ukrainian Journal of Laboratory Medicine 2025-04-03

This article highlights the significance of updated recommendations from European Federation Clinical Chemistry and Laboratory Medicine (EFLM) – Urinalysis Guideline 2023. The guidelines emphasize need for standardizing laboratory procedures to enhance research quality reduce diagnostic errors. Based on current scientific data international standards, these aim ensure high reliability accuracy results. implementation urinalysis guideline has potential significantly improve effectiveness,...

10.62151/2786-9288.2.3.2024.01 article EN cc-by Ukrainian Journal of Laboratory Medicine 2024-10-12

Gonorrhea is the second most common sexually transmitted infection spreading worldwide and a serious public health problem. How�ever, further data are required to improve management of gonorrhea. Our aim was review features gonococcal characterize challenges its management. A retrospective descriptive study medical records 136 adult patients with gonorrhea that visited Ternopil Regional Sexually Transmitted Infections Clinic (Ukraine) in 2013-2018 performed. The male-to-female ratio 6.6:1....

10.25122/jml-2019-0170 article EN Journal of Medicine and Life 2020-01-01

Introduction and aim. Information concerning lactoferrin interleukin-8 (IL-8) local levels in breast milk are not numerous requires further research. The aim of this study was to determine the content patients with lactational mastitis, identify new potential markers for assessing activity inflammatory process mammary gland. Material methods. This analyzed 30 women lactostasis (group I), 37 mastitis II) healthy lactating (age 26±5 years old). determined by enzyme-linked immunosorbent assay....

10.15584/ejcem.2024.1.22 article EN cc-by European Journal of Clinical and Experimental Medicine 2024-03-30

The article presents the experience of obtaining hematopoietic stem cells (HSCs) and their immunophenotyping using method flow cytometry at State Institution "Institute Blood Pathology Transfusion Medicine National Academy Medical Sciences Ukraine", Lviv. Lviv, Ukraine. Hematopoietic are key elements in system basis for bone marrow transplantation, which is used to treat various oncohematologic diseases, including leukemia, lymphoma, others. results analysis HSCs different patients with...

10.62151/2786-9288.2.2.2024.06 article EN Ukrainian Journal of Laboratory Medicine 2024-07-02

This publication highlights some of the key achievements and challenges faced by laboratory medicine in 2024. It outlines global trends, including automation, application artificial intelligence, advancements personalized medicine, more. The extraordinary resilience Ukrainian community is particularly emphasized, showcasing its ability to adapt challenging conditions implement innovative solutions even during times significant adversity. article demonstrates how high professionalism, process...

10.62151/2786-9288.2.4.2024.01 article EN cc-by-nc Ukrainian Journal of Laboratory Medicine 2024-12-30

The article highlights the key aspects of Anderson-Fabry disease, a rare genetic disorder characterized by lipid accumulation in cells due to deficiency enzyme α-galactosidase A. study provides detailed review history, primary causes, and pathogenetic mechanisms disease. It describes various internal organ damages associated with pathology. Special attention is given laboratory markers such as Lyso-Gb3, Gb3, other indicators, which play critical role diagnosis monitoring condition. Modern...

10.62151/2786-9288.2.4.2024.04 article EN cc-by-nc Ukrainian Journal of Laboratory Medicine 2024-12-30

Резюме. У презентованій статті наведено зміни показників клітинного імунітету в пацієнтів з ішемічною хворобою серця (ІХС) та при ускладненні метаболічним синдромом (МС). ІХС є найпоширенішою формою серцевих захворювань. Основним пусковим механізмом у розвитку серцево-судинних захворювань (ССЗ) запальні процеси метаболічний синдром, що супроводжуються розвитком імунодефіцитних станів. Мета дослідження – вивчити стан на тлі метаболічного синдрому. Матеріали і методи. Обстежено 120 із ІХС, них...

10.11603/bmbr.2706-6290.2022.2.13042 article UK cc-by Bulletin Of Medical And Biological Research 2022-08-07

<p><em>Досліджено</em><em> </em><em>вміст</em><em> </em><em>IL-8 </em><em>у</em><em> </em><em>сироватці</em><em> </em><em>к</em><em>рові</em><em> </em><em>та</em><em> </em><em>г</em><em>р</em><em>у</em><em>дном</em><em>у</em><em>...

10.11603/1681-2557.2015.v17.i1.4098 article UK Медична хімія 2015-05-27

DYNAMICS OF THE ALKALINE PHOSPHATHASE BONE ISOENZYM CONTENT IN BLOOD SERUM PATIENTS WITH UNCOMPLICATED MANDIBULAR FRACTURES

10.29256/v.02.01.2018.escbm21 article EN Biological Markers in Fundamental and Clinical Medicine (collection of abstracts) 2018-03-24

Objective — to investigate immuno-metabolic homeostasis in patients with new and recurrent cases of destructive forms multidrug-resistant pulmonary tuberculosis (MDR-PTB) after treatment bedaquiline linezolid. Materials methods. A clinical laboratory examination 175 people MDR-PTB (89 86 MDR-PTB). The study was performed before total leukocytes count (L), the leukocyte differential (leukocyte formula), determined all subjects, content populations subpopulations lymphocytes were calculated...

10.30978/tb2021-3-30 article EN Tuberculosis Lung Diseases HIV Infection 2021-10-01

<p>The urgency of the problems caused by frequent research septic complications in patients with acute calculous<br />cholecystitis (ACC), accompanied increase endogenous intoxication. The study involved ACC<br />complicated choledocholithiasis, cholangitis and local peritonitis. studies found an levels of<br />total serum bilirubin all groups due to direct fraction, indicating obstructive jaundice. ratio bilirubin<br />monoglyukuronid/diglucuronide more than...

10.11603/mcch.2410-681x.2015.v17.i3.5049 article EN cc-by Medical and Clinical Chemistry 2015-10-26

The aim of the research was to investigate cell immunity in patients with abdominal tuberculosis improve diagnostic process and treatment. It shown that under condition T-cell immunodeficiency is formed by cause domination apoptosis. Activation CD8+ CD16+ lymphocyte subsets characterize chronic inflammation. Also I type hypersensitivity occures

10.11603/mcch.2410-681x.2015.v17.i2.4860 article EN Medical and Clinical Chemistry 2015-06-14

Influence of risk factors and invasive treatment methods on the course acute chronic forms coronary heart disease" (state registration number 0116U004512), "Influence arterial hypertension, type 2 diabetes, excess weight, smoking subclinical hypothyroidism occurrence disease", state 0120U105778. Introduction.Data from World Health Organization (WHO) show that cardiovascular diseases (CVD) are main cause death worldwide [1].More than 4 million people in Europe die them yearly [2, 3].Among all...

10.29254/2077-4214-2023-2-169-269-277 article EN cc-by-nd Bulletin of Problems Biology and Medicine 2023-01-01

Вступ. Сприятливими факторами для розвитку запального процесу в молочній залозі є лактостаз, наявність патогенної флори, а також зниження імунобіологічної реактивності організму жінки. Запальний процес спричиняє і регулює низка медіаторів. Зокрема, прозапальний інтерлейкін-1β індукує запальну реакцію гострофазну відповідь, здійснює взаємозв’язок між неспецифічною та специфічною ланками імунітету. Дослідники вважають прокальцитонін найбільш перспективним індикатором септичного процесу, який...

10.11603/mcch.2410-681x.2023.i2.13972 article UK cc-by Medical and Clinical Chemistry 2023-07-11

For many years, and to this day, cardiovascular disease has been remains the leading cause of death worldwide. Cardiovascular diseases mainly affect people in countries with middle low living standards.
 The aim study was find out peculiarities lipid, carbohydrate, hormonal changes patients coronary heart against background metabolic syndrome.
 Materials methods: 120 verified were examined, including 60 without syndrome syndrome. control group consisted 30 practically healthy...

10.15587/2519-4798.2023.285594 article EN ScienceRise Medical Science 2023-05-31

Introduction. Cardiovascular diseases are the cause of disability among younger and population. Taking into account frequency cardiovascular diseases, severity course their lethality, study this topic remains one biggest urgent problems medicine. It is known from scientific sources that metabolic syndrome increases risk mortality them by 1.5-3 times. However, it often not possible to identify in time, because nothing bothers patients, which makes much more difficult estimate its...

10.62151/2786-9288.1.2.2023.04 article EN cc-by-nc Ukrainian Journal of Laboratory Medicine 2023-12-30

Introduction. The most common cause of vision loss in case diabetes is retinal pathology (diabetic retinopathy). study blood pressure levels serum patients with nonproliferative diabetic retinopathy type 2 a promising direction research the aim studying links pathogenesis development this pathology, diagnosis, and possible prognosis disease
 study: to find out peculiarities humoral immune dysfunction against background metabolic syndrome
 Results discussion. PSA increases...

10.62151/2786-9288.1.1.2023.01 article EN cc-by-nc Ukrainian Journal of Laboratory Medicine 2023-09-01

Introduction. Today, the pathology of cardiovascular system is one most common and fatal diseases. Cardiovascular diseases are cause disability among younger population. Taking into account frequency diseases, severity course their lethality, study this topic remains urgent problems medicine, in particular cardiology.
 The aim study. Consider modern views on pathogenesis coronary heart disease against background metabolic syndrome role immune system.
 Conclusions. Ischemic leading...

10.62151/2786-9288.1.2.2023.08 article EN cc-by-nc Ukrainian Journal of Laboratory Medicine 2023-12-30
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