Joaquim Cesar Sousa
A5009009848- SARS-CoV-2 and COVID-19 Research
- Plant Virus Research Studies
- vaccines and immunoinformatics approaches
- Virology and Viral Diseases
- Viral Infections and Outbreaks Research
- Retinal and Optic Conditions
- COVID-19 epidemiological studies
- CRISPR and Genetic Engineering
- Ocular Diseases and Behçet’s Syndrome
Fundação Oswaldo Cruz
2022
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has infected almost 200 million people worldwide by July 2021 and the pandemic been characterized infection waves of viral lineages showing distinct fitness profiles. The simultaneous a single individual two SARS-CoV-2 may impact COVID-19 disease progression provides window opportunity for recombination emergence new with differential phenotype. Several hundred are currently well phylogenetically defined, but main factors have...
The COVID-19 epidemic in Brazil experienced two major lineage replacements until mid-2021. first was driven by P.2, late 2020, and the second Gamma, early 2021. To understand how these SARS-CoV-2 lineages spread Brazil, we analyzed 11,724 genomes collected throughout country between September 2020 April Our findings indicate that P.2 probably emerged July Rio de Janeiro state Gamma November Amazonas state. Both states were main hubs of viral disseminations to other Brazilian locations. We...
The SARS-CoV-2 variant of concern (VOC) Delta was first detected in India October 2020. imported cases the Brazil were identified April 2021 southern region, followed by more different regions during following months. By early September 2021, already dominant southeastern (87%), (73%), and northeastern (52%) Brazilian regions. This study aimed to understand spatiotemporal dissemination dynamics Brazil. To this end, we employed a combination maximum likelihood (ML) Bayesian methods...
Abstract The SARS-CoV-2 has infected almost 200 million people worldwide by July 2021 and the pandemic been characterized infection waves of viral lineages showing distinct fitness profiles. simultaneous a single individual two provides window opportunity for recombination emergence new with differential phenotype. Several hundred are currently well but main factors have precluded major coinfection/codetection analysis thus far: i) low diversity during first year which limited identification...