A5100420719- RNA modifications and cancer
- Liver Disease Diagnosis and Treatment
- Lipid metabolism and biosynthesis
- Fuel Cells and Related Materials
- Cancer-related gene regulation
- Sphingolipid Metabolism and Signaling
- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Peptidase Inhibition and Analysis
- Cardiac Structural Anomalies and Repair
- Gastroesophageal reflux and treatments
University of South China
2023
Changsha Central Hospital
2021-2023
Sichuan Agricultural University
2022
Ministry of Agriculture and Rural Affairs
2022
Tianjin University
2020
Tianjin Medical University Cancer Institute and Hospital
2020
Tianjin Children's Hospital
2020
Our previous study described the mechanism of goose fatty liver formation from cell culture and transcriptome. However, how lipidome response to overfeeding is unclear. In this study, we used same batch geese (control group corn flour group) explore changes underlying metabolic mechanisms formation. Liquid chromatography-mass spectrometry (LC-MS) was provided detection. Liver lipidomics profiles analysis performed by principal component (PCA), partial least squares-discriminant (PLS-DA)...
What is the central question of this study? effect fat mass and obesity-associated protein (FTO) on energy metabolism in hypoxia-reoxygenation (H/R)-induced cardiomyocytes? main finding its importance? FTO modification N6 -methyladenosine (m6 A) associated with myocardial cell disorder. reduced m6 A level sarcoplasmic/endoplasmic reticulum calcium ATPase 2a (SERCA2a) mRNA through demethylation, thus promoting SERCA2a expression, maintaining homeostasis, improving H/R cardiomyocytes.Energy...
Oropharyngeal squamous cell carcinoma (OPSCC) is a kind of head and neck, its incidence on the rise in recent years. A variety prognostic markers for OPSCC have been reported many studies, but they are expensive or difficult to obtain. So, we retrospectively studied significance cytokeratin 19 soluble fragment (Cyfra21-1) patients with OPSCC, order provide theoretical basis accurate prognosis assessment.A retrospective analysis clinicopathological data 85 concurrent radiotherapy chemotherapy...