A5021490585- Polyamine Metabolism and Applications
- Animal Nutrition and Physiology
- Selenium in Biological Systems
- Cannabis and Cannabinoid Research
- Amino Acid Enzymes and Metabolism
- Gut microbiota and health
- Liver Disease Diagnosis and Treatment
- Effects of Environmental Stressors on Livestock
- Reproductive Biology and Fertility
- Epigenetics and DNA Methylation
- Lipid metabolism and biosynthesis
- Adipose Tissue and Metabolism
- Sperm and Testicular Function
- Autophagy in Disease and Therapy
- Genetic Mapping and Diversity in Plants and Animals
- Rabbits: Nutrition, Reproduction, Health
- Agronomic Practices and Intercropping Systems
- Pharmacological Effects of Natural Compounds
- Meat and Animal Product Quality
- Biochemical effects in animals
- Ruminant Nutrition and Digestive Physiology
- Animal Genetics and Reproduction
- Trace Elements in Health
- Bee Products Chemical Analysis
- Agriculture Sustainability and Environmental Impact
Sichuan Agricultural University
2015-2025
Ministry of Agriculture and Rural Affairs
2022-2025
Xiamen University of Technology
2018
National Institute of Animal Science
2008
Hankyong National University
2008
With the increasing of global mean surface air temperature, heat stress (HS) induced by extreme high temperature has become a key factor restricting poultry industry. Liver is main metabolic organ broilers, HS induces liver damage and disorders, which impairs health broilers affects food safety. As an essential trace element for animals, selenium (Se) involves in formation antioxidant system, its biological functions are generally mediated selenoproteins. However, mechanism Se against...
Spermidine have been reported a role in antioxidative, antiaging, and antiinflammatory. Oxidative stress causes granulosa cell (GC) apoptosis, follicular atresia, impairs poultry reproductive functions. Studies found that autophagy is the protective mechanism against antioxidant apoptosis cells. However, relationship between spermidine-induced autophagy, oxidative stress, goose GCs remains unclear. In this study, we investigated to mediate spermidine effects on alleviation of GCs. Follicular...
Information regarding relationships between forage yield and soil enzymes of legume-grass mixtures under nitrogen (N) fertilization can guide the decision-making during sustainable production. The objective was to evaluate responses yield, nutritional quality, nutrients, enzyme activities different cropping systems various N inputs. Alfalfa (Medicago sativa L.), white clover (Trifolium repens orchardgrass (Dactylis glomerata tall fescue (Festuca arundinacea Schreb.) were grown in...
In the present study, chronic heat stress (CHS) broiler model was developed to investigate potential protection mechanism of organic selenium (selenomethionine, SeMet) on CHS-induced skeletal muscle growth retardation and poor meat quality. Four hundred Arbor Acres male broilers (680 ± 70 g, 21 d old) were grouped into 5 treatments with 8 replicates 10 per replicate. Broilers in control group raised a thermoneutral environment (22 2 °C) fed basal diet. The other four exposed hyperthermic...
Faba bean (Vicia faba L.), although a kind of high-quality and high-yield forage, could hardly achieve great quality silage because its high buffering capacity. Mixed with forage wheat (Triticum aestivum L.) or oat (Avena sativa at different ratios improve the fermentation bacterial community. Compared 100% (BS), mixed improved quality, not only increased lactic acid production reduced pH, but propionic ammonia nitrogen. The chemical compositions (BT) were better than that (BO) silage, 3:7,...
Spermidine is a naturally occurring polyamine compound that has many biological functions, such as inducing autophagy and anti-inflammatory anti-aging effects. can affect follicular development thus protect ovarian function. In this study, ICR mice were fed exogenous spermidine drinking water for three months to explore the regulation of function by spermidine. The results showed number atretic follicles in ovaries spermidine-treated was significantly lower than control group. Antioxidant...
The skeletal muscle of pigs is vulnerable to oxidative damage, resulting in growth retardation. Selenoproteins are important components antioxidant systems for animals, which generally regulated by dietary selenium (Se) level. Here, we developed the stress (DOS)-inducing pig model investigate protective effects selenoproteins on DOS-induced retardation.Dietary caused porcine damage and retardation, accompanied mitochondrial dysfunction, endoplasmic reticulum (ER) stress, protein lipid...
Introduction Intestinal health is very important to the of livestock and poultry, even a major determining factor in performance poultry production. Spermidine type polyamine that commonly found variety foods, can resist oxidative stress, promote cell proliferation regulate intestinal flora. Methods In this study, we explored effects spermidine on under physiological states or stress conditions by irrigation with intraperitoneal injection 3-Nitropropionic acid (3-NPA) Sichuan white goose....
The mechanism of action by which oxidative stress induces granulosa cell apoptosis, plays a vital role in initiating follicular atresia, is not well understood. In the present study, effect 3-nitropropionic acid (3-NPA) on and apoptosis cells geese was investigated. Our results showed that treatment with 3-NPA at 5.0 mmol/l for 24 h increased intracellular reactive oxygen species (ROS) production 25.4% decreased viability 45.5% (
Heat stress (HS) has a negative impact on the intestinal barrier and immune function of pigs. Selenium (Se) may improve health through affecting selenoproteins. Thus we investigate protective effect new organic Se (2-hydroxy-4-methylselenobutanoic acid, HMSeBA) jejunal damage in growing pigs upon HS integrate potential roles corresponding selenoproteins.HS decreased villus height increased (P < 0.05) protein abundance HSP70, downregulated levels tight junction-related proteins (CLDN-1 OCLD)....
Weaning often induces oxidative stress and inflammatory response in piglets. This study investigated the effects of dietary licorice flavonoids powder (LFP) supplementation on antioxidant capacity immunity weaned Notably, 96 Landrace × Yorkshire Duroc (DLY) piglets were randomly allocated to four treatments with 6 replicates (4 animals per replicate) fed diet 0, 50, 150, 250 mg/kg LFP, respectively. The trial lasted for 5 weeks. results showed that LFP effectively increased liver index (P <...
Abstract Copper exposure poses potential detrimental effects on both public and ecosystem health. Spermidine, an antioxidant, has shown promise in reducing oxidative stress inflammation within the liver. However, its specific role mitigating copper‐induced hepatic cuproptosis disturbances copper metabolism remains unexplored. Consequently, this research aims to investigate examine impact of spermidine related metabolism. In study, we established a model liver toxicity by feeding C57BL/6 mice...
The identification of the differential expression genes in ovaries egg-laying and prelaying Zi geese is required to improve laying performance geese. In present study, suppression subtractive hybridization reverse dot-blot were employed identify such genes, using ovary as a model. Furthermore, profiling estrogen receptor 1, 2, follicle stimulating hormone receptor, prolactin ferritin H chain, differentially expressed unknown gene 08 from was performed by quantitative real-time PCR. Total RNA...
In contrast to the situation in mammals, very little is known about molecular mechanisms regulating early avian ovarian development. This study aimed investigate dynamic changes histomorphology as well genome-wide transcriptome and chromatin accessibility landscapes of goose ovary during late embryonic post-hatching stages. Results from hematoxylin-eosin, periodic acid-Schiff, anti-CVH immunohistochemical stainings demonstrated that programmed oocyte loss, nest breakdown primordial follicle...
Chronic heat stress (CHS) induces metabolic changes in skeletal muscle from growth to maintenance that jeopardizes performance, carcass traits, and meat quality of pigs. We investigated the protective effect dietary organic selenium (hydroxy-4-methylselenobutanoic acid, OH-SeMet) on CHS-induced damages growing pigs, corresponding responses selenoproteins. A total 40 ((Landrace ×Yorkshire) × Duroc) pigs with an average live weight 49.64 ± 2.48 kg were used this 4-week trial. Pigs randomly...
Abstract Licorice flavonoids, a bioactive substance derived from glycyrrhiza, have been reported for many pharmacological properties and are beneficial to animal health. This study aimed explore the effects of licorice flavonoids powder (LFP) on growth performance intestinal health piglets. A total 96 weaned piglets were randomly assigned into four treatments supplemented with 0, 50, 150 250 mg/kg LFP 5 weeks. Dietary supplementation tended increase ( p = 0.068) average daily gain (ADG)...
Intercropping improves land-use efficiency under conditions of limited land and resources, but no information is currently available pertaining to silage quality based on whole-plant utilization. Therefore, a two-year field experiment was conducted with the following conditions: three maize–soybean strip intercropping patterns (SIPs), comprising two maize rows along two, three, or four soybean (2M2S, 2M3S, 2M4S, respectively); sole cropping (SM) (SS). The aim evaluate biomass yield each...
To comprehensively provide insight into goose fatty liver formation, we performed an integrative analysis of the transcriptome, lipidome, and amino acid metabolome, as well peripheral adipose tissue transcriptome using samples collected from overfed geese normally fed geese. Transcriptome showed that metabolism pathways were mainly enriched in glucolipid metabolism, inflammation response, cell cycle; cooperatively regulated lipid accumulation during overfeeding. Liver lipidome patterns...
1. A study was conducted to investigate the effect of spermidine on cuproptosis in granulosa cells goose ovarian follicles. Granulosa from F2-F5 grade follicles Sichuan white geese were isolated and cultured.2. Copper sulphate, chloroquine administered (GC). The GC activity, intracellular Cu2+ content, antioxidant enzyme expression levels genes proteins related autophagy determined.3. results showed that significantly decreased reactive oxygen species (ROS) levels, mitochondrial membrane...