A5101639190- Catalytic C–H Functionalization Methods
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Radical Photochemical Reactions
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Analysis
- Peptidase Inhibition and Analysis
- Proteoglycans and glycosaminoglycans research
- Catalytic Cross-Coupling Reactions
- Analytical Chemistry and Chromatography
- Polymer Nanocomposites and Properties
- Synthetic Organic Chemistry Methods
- Environmental Quality and Pollution
- Mycorrhizal Fungi and Plant Interactions
- Chemical Synthesis and Reactions
- Crystal structures of chemical compounds
- Polymer Nanocomposite Synthesis and Irradiation
- Plant Pathogens and Fungal Diseases
- Wind Turbine Control Systems
- Cyclopropane Reaction Mechanisms
- Microfluidic and Capillary Electrophoresis Applications
- Water Resources and Governance
- Advanced battery technologies research
- CO2 Reduction Techniques and Catalysts
- Quasicrystal Structures and Properties
Guizhou University
2025
University of Wisconsin–Madison
2019-2024
Chongqing University
2007-2024
Taizhou University
2024
Hunan Provincial People's Hospital
2022
First Affiliated Hospital of Xinjiang Medical University
2022
Xinjiang Medical University
2022
Shandong Agricultural University
2022
Hunan Normal University
2022
Hubei University
2019
ConspectusCascade reactions represent a class of ideal organic because they empower efficiency, elegance, and novelty. However, development cascade remains daunting task for synthetic chemists. Radicals are known to be well suited reactions. Compared with widely used carbon-based radicals, nitrogen-based such as neutral aminyl radicals protonated (amine radical cations), underutilized, although behind some notable methods the Hofmann–Löffler–Freytag reaction. The constraint on their usage is...
Abstract While ketones are among the most versatile functional groups, their synthesis remains reliant upon reactive and low‐abundance starting materials. In contrast, amide formation is most‐used bond‐construction method in medicinal chemistry because reliable draws large diverse substrate pools. A new for of presented here that from same substrates used bond synthesis: amines carboxylic acids. nickel terpyridine catalyst couples N‐alkyl pyridinium salts with situ formed acid fluorides or...
Abstract Synthesis of the C−C bonds ketones relies upon one high‐availability reagent (carboxylic acids) and low‐availability (organometallic reagents or alkyl iodides). We demonstrate here a ketone synthesis that couples two different carboxylic acid esters, N ‐hydroxyphthalimide esters S ‐2‐pyridyl thioesters, to form aryl dialkyl in high yields. The keys this approach are use nickel catalyst with an electron‐poor bipyridine terpyridine ligand, THF/DMA mixed solvent system, ZnCl 2 enhance...
Visible-light-mediated photoredox reactions have recently emerged as a powerful means for organic synthesis and thus generated significant interest from the chemistry community. Although mechanisms of these been probed by number techniques such NMR, fluorescence quenching, laser flash photolysis various degrees success has achieved, mechanistic ambiguity still exists (for instance, involvement chain mechanism is under debate) because lack structural information about proposed short-lived...
Carbon-heteroatom bonds, most often amide and ester are the standard method to link together two complex fragments because carboxylic acids, amines, alcohols ubiquitous reactions reliable. However, C-N C-O linkages a metabolic liability they prone hydrolysis. While C(sp
Abstract We report the first example of an intermolecular [4+2] annulation cyclobutylanilines with alkynes enabled by visible‐light photocatalysis. Monocyclic and bicyclic successfully undergo terminal internal to generate a wide variety amine‐substituted cyclohexenes including new hydrindan decalin derivatives good excellent diastereoselectivity. The reaction is overall redox neutral perfect atom economy.
The CD44 gene encodes several protein isoforms due to alternative splicing and post translational modifications. Given that variant isoform 9 (CD44v9) is expressed within Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) glands during repair, CD44v9 may be play a funcitonal role the process of regeneration gastric epithelium. Here we hypothesize marks regenerative cell lineage responsive infiltrating macrophages Ulcers were induced in CD44-deficient (CD44KO) C57BL/6 (BL6) mice by...
Abstract Synthesis of the C−C bonds ketones relies upon one high‐availability reagent (carboxylic acids) and low‐availability (organometallic reagents or alkyl iodides). We demonstrate here a ketone synthesis that couples two different carboxylic acid esters, N ‐hydroxyphthalimide esters S ‐2‐pyridyl thioesters, to form aryl dialkyl in high yields. The keys this approach are use nickel catalyst with an electron‐poor bipyridine terpyridine ligand, THF/DMA mixed solvent system, ZnCl 2 enhance...
Apple replant disease (ARD) is the most serious threat facing apple industry globally. ARD mainly manifested as decreased plant growth, root rot disease, and considerable yield loss. Microbial factors are dominant leading to occurrence of ARD. Research on soil-borne pathogenic fungi in China limited. In present study, we selected 16 replanting orchards from Northwest Loess region around Bohai Gulf. Diseased roots rhizosphere soil healthy trees showing symptoms were sampled at random....
Abstract While ketones are among the most versatile functional groups, their synthesis remains reliant upon reactive and low‐abundance starting materials. In contrast, amide formation is most‐used bond‐construction method in medicinal chemistry because reliable draws large diverse substrate pools. A new for of presented here that from same substrates used bond synthesis: amines carboxylic acids. nickel terpyridine catalyst couples N‐alkyl pyridinium salts with situ formed acid fluorides or...
While the sensory neuron membrane protein (SNMP) family has been linked to sex pheromone detection, roles in other olfactory-associated and nonolfactory functions have not as well-defined. In this study, four SNMP genes were identified for white-backed planthopper (Sogatella furcifera; WBPH), a major pest of rice plants. Tissue-specific transcriptomic data indicated that all SfurSNMPs are only expressed antennae varying levels but also observed several non-olfactory tissues. RNA interference...
During the investigations of macrofungi resources in Zhejiang Province, China, an interesting wood rot fungus was collected. Based on morphological and molecular phylogenetic studies, it is described as a new species, Anthracophyllum sinense. A. sinense characterized by its sessile, charcoal black pleurotoid pileus, sparse lamellae occasionally branching, clavate basidia with long sterigmata [(3-)6–7(-8) μm], non-heteromorphous cystidia. establishes separate lineage close to archeri lateritium tree.
We herein report a visible-light-mediated heterogeneous [4+2] annulation of N-cyclobutylanilines with alkynes catalyzed by self-doped Ti
Carbonheteroatom bonds, most often amide and ester are the standard method to link together two complex fragments be-cause carboxylic acids, amines, alcohols ubiquitous reactions reliable. However, CN CO linkages a metabolic liability because they prone hydrolysis. While C(sp2)–C(sp3) preferable in many cases, methods make them require different starting materials or less functional-group compatible. We show here new, decarbonylative reaction that forms bonds from of activated acids (via...
A pH-responsive methylcellulose-g-poly(sodium acrylate)/attapulgite (MC-g-PNaA/APT) nanocomposite superabsorbent was prepared by the free-radical solution polymerization of methylcellulose (MC), sodium acrylate (NaA) and nanoscale attapulgite (APT) in presence crosslinker N,N′-methylene-bis-acrylamide (MBA). The structure morphology were characterized FTIR, FESEM, TEM, XRD EDS techniques, effects amount MBA, MC APT nanorods on swelling behaviors also evaluated. Results indicate that NaA has...
A new strategy for the synthesis of ketones is presented based upon decarboxylative coupling N-hydroxyphthalimide (NHP) esters with S-2-pyridyl thioesters. The reactions are selective cross-coupled product because NHP act as radical donors and thioesters acyl donors. reaction conditions general mild, over 40 examples presented, including larger fragments 20-mer peptide Exendin(9-39) on solid support.
Subject: Perioperative regulation of coagulation function through heparin in patients undergoing cardiac surgery with cardiopulmonary bypass is an important part performing surgery, and postoperative bleeding due to abnormal caused by differences sensitivity different individuals independent risk factor for complications death. Method: Using online database, 10 miRNAs interacting AT-III FX genes were predicted. Patients divided into three groups according the difference activated clotting...