Shiri Kushnir

ORCID: 0000-0003-2359-5249
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About
Contact & Profiles
Research Areas
  • Pituitary Gland Disorders and Treatments
  • Adrenal and Paraganglionic Tumors
  • Growth Hormone and Insulin-like Growth Factors
  • Adrenal Hormones and Disorders
  • Venous Thromboembolism Diagnosis and Management
  • Pediatric Urology and Nephrology Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Bacterial Identification and Susceptibility Testing
  • Inhalation and Respiratory Drug Delivery
  • Urinary Tract Infections Management
  • Urinary Bladder and Prostate Research
  • Artificial Intelligence in Healthcare
  • Antimicrobial Resistance in Staphylococcus
  • Diabetes Treatment and Management
  • Atrial Fibrillation Management and Outcomes
  • Healthcare cost, quality, practices
  • Acute Myocardial Infarction Research
  • Maternal and fetal healthcare
  • Liver Disease Diagnosis and Treatment
  • Pregnancy and preeclampsia studies
  • Retinal and Optic Conditions
  • Global Cancer Incidence and Screening
  • Iron Metabolism and Disorders
  • Potassium and Related Disorders
  • Thyroid Cancer Diagnosis and Treatment

Rabin Medical Center
2017-2025

Tel Aviv University
2024

Oregon Health & Science University
2024

Neurological Surgery
2024

Urinary tract infections (UTIs) in childhood are common and associated with considerable acute morbidity long-term complications. The need for updated data to optimize empiric antibiotic therapy is crucial. We aimed investigate the pathogens causing pediatric community acquired UTIs, their correlation demographic characteristics, trends antimicrobial resistance. This nationwide cross-sectional study included all 53,203 children (<18 years) diagnosed UTI outpatient clinics following...

10.3390/pathogens13030201 article EN cc-by Pathogens 2024-02-24

Abstract Objective Cancer incidence in patients with endogenous Cushing's syndrome (CS) has never been established. Here, we aimed to assess the cancer risk CS as compared individually matched controls. Design A nationwide retrospective cohort study of diagnosed between 2000 and 2023 using database Clalit Health Services Israel. Methods Patients adrenal carcinoma or ectopic were excluded. a 1:5 ratio, controls for age, sex, socioeconomic status, body mass index. The primary outcome was...

10.1093/ejendo/lvae098 article EN European Journal of Endocrinology 2024-07-27

Abstract Context Leukocytosis frequently noted in Cushing’s syndrome (CS), along with other blood cell changes caused by direct and indirect cortisol effects. Objective Assess baseline white (WBC) profile CS patients compared to controls WBC pre- post-remission after surgical treatment for CS. Design A comparative nationwide retrospective cohort study. Setting Data from Clalit Health Services database. Patients 297 (mean age 51 ± 16.1 years, 73.0% women) 997 age-, sex-, body mass index-,...

10.1007/s40618-025-02535-2 article EN cc-by Journal of Endocrinological Investigation 2025-01-28

Data on the risk of stroke in patients with hyperprolactinemia are limited. This study aimed to evaluate association between and ischemic a large cohort identify predictors this population. was retrospective comparing incidence dopamine agonist-treated matched controls 1:5 ratio. The primary outcome diagnosis stroke. included 2440 DA-treated (mean age ± SD: 38.42 14.57 years, 60.2% women) 12,022 38.15 14.36 60.8% women). Ischemic occurred 195 (8.0%) 747 (6.21%) (adjusted HR 1.24, 95% CI...

10.1111/jne.13494 article EN Journal of Neuroendocrinology 2025-02-09

Abstract Objective Endogenous Cushing's syndrome (CS) has been linked with an increased risk of cancer. We aimed to evaluate the association between cancer and disease remission post-surgery in adrenal CS (CD). Design A nationwide retrospective matched-cohort study patients diagnosed 2000-2023 Israel, using Clalit Health Services’ database. Methods Patients were matched 1:5 controls by age, sex, socioeconomic status, BMI. Remission status was assessed within two years after diagnosis CS. The...

10.1093/ejendo/lvaf028 article EN European Journal of Endocrinology 2025-02-25

Abstract Objective To investigate the impact of Sodium-glucose cotransporter 2 (SGLT2) inhibitors on incidence, complications, and therapeutic demands anemia in patients with diabetes utilizing real-world data, compared to treatment dipeptidyl peptidase 4 (DPP4) inhibitors. Patients Methods In this retrospective cohort study, dataset was sourced from data repositories Clalit Health Services. Since January 1, 2016 through December 31, 2021 we identified type who received SGLT2 them a matched...

10.1210/clinem/dgaf184 article EN publisher-specific-oa The Journal of Clinical Endocrinology & Metabolism 2025-03-22

Patients with endogenous Cushing's syndrome (CS) have elevated mortality, particularly during active disease. A recent meta-analysis reported reduced mortality rates after 2000 in adrenal CS and Cushing disease (CD), though many studies lacked population-matched controls. Nationwide retrospective study (2000-2023) Israel using the Clalit Health Services database to assess all-cause patients matched 1:5 controls by age, sex, socioeconomic-status, BMI. Primary outcome was mortality. Secondary...

10.1093/ejendo/lvaf059 article EN cc-by European Journal of Endocrinology 2025-03-30

Abstract Burden of COVID-19 on Hospitals across the globe is enormous and has clinical economic implications. In this retrospective study including consecutive adult patients with confirmed SARS-CoV-2 who were admitted between 3/2020 30/9/20, we aimed to identify post-discharge outcomes risk factors for re-admission among hospitalized patients. Mortality re-admissions documented a median post discharge follow up 59 days (interquartile range 28,161). Univariate multivariate analyses...

10.1038/s41598-021-96716-7 article EN cc-by Scientific Reports 2021-08-31

Background Venous thromboembolism (VTE) is considered a preventable cause of mortality. The evidence for the benefit VTE prophylaxis in acute medical patients non-conclusive. Meta-analysis RCTs failed to demonstrate reduction all-cause mortality, while showing higher risk bleeding. Israeli Ministry Health has instructed assess all using Padua Prediction Score, without mandating prophylaxis. Aim To evaluate effect filling score on clinical outcomes and rates. Methods Retrospective Study was...

10.1371/journal.pone.0292661 article EN cc-by PLoS ONE 2024-02-07

<title>Abstract</title> Purpose The study aimed to characterize the erythrocytic profile in patients with Cushing’s syndrome (CS) versus controls from normal population according etiology, sex, presence of diabetes mellitus (DM) and hypercortisolemia remission status. Methods This retrospective cohort analysis compared parameters between CS pituitary (CD) adrenal (aCS) etiology age, body mass index (BMI) socioeconomic status-matched a 1:5 ratio. Laboratory values at baseline were calculated...

10.21203/rs.3.rs-3953494/v1 preprint EN cc-by Research Square (Research Square) 2024-02-15

Abstract Purpose Glaucoma incidence in patients with endogenous Cushing's syndrome (CS) has never been established. We aim to assess the risk for glaucoma among CS compared controls and determine age of disease onset. Methods A nationwide retrospective matched‐cohort study diagnosed between 2000 2023. Patients were matched a 1:5 ratio, control group individually age, sex, socioeconomic status body mass index. Main outcomes Results total 609 [396 women (65%); mean 48.1 ± 17 years] included...

10.1111/aos.16787 article EN cc-by-nc-nd Acta Ophthalmologica 2024-11-05
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