A5100371310- Graphene research and applications
- Quantum and electron transport phenomena
- Topological Materials and Phenomena
- Cosmology and Gravitation Theories
- ZnO doping and properties
- Diamond and Carbon-based Materials Research
- Galaxies: Formation, Evolution, Phenomena
- Cancer-related Molecular Pathways
- Ga2O3 and related materials
- Gas Sensing Nanomaterials and Sensors
- Semiconductor materials and devices
- Semiconductor Quantum Structures and Devices
- Black Holes and Theoretical Physics
- NF-κB Signaling Pathways
- Microtubule and mitosis dynamics
- Copper-based nanomaterials and applications
- Cell death mechanisms and regulation
- Advancements in Semiconductor Devices and Circuit Design
- 2D Materials and Applications
- Cancer, Hypoxia, and Metabolism
- Cold Atom Physics and Bose-Einstein Condensates
- Protein Kinase Regulation and GTPase Signaling
- Strong Light-Matter Interactions
- Neuroblastoma Research and Treatments
- Ubiquitin and proteasome pathways
Columbia University
1999-2018
Wuhan University
2012
Peking University
2010-2011
Brookhaven National Laboratory
2004-2009
University of Chicago
2009
E2F transcription factor is subject to stringent regulation by a variety of molecules. We recently observed that prohibitin, potential tumor suppressor protein, binds the retinoblastoma (Rb) protein and represses transcriptional activity. Here we demonstrate prohibitin requires marked box region for repression; further, can effectively inhibit colony formation induced overexpression E2F1 in T47D cells. Prohibitin was also found interact with signaling kinase c-Raf-1, Raf-1 could reverse...
ABSTRACTCells initiate proliferation in response to growth factor stimulation, but the biochemical mechanisms linking signals received at cell surface receptors cycle regulatory molecules are not yet clear. In this study, we show that signaling molecule Raf-1 can physically interact with Rb and p130 proteins vitro vivo interaction be detected mammalian cells without overexpressing any component. The binding of occurs subsequent mitogen only proliferating cells. inactivate function reverse...
We show that the abundance and redshift distribution ($dN/dz$) of galaxy clusters in future high-yield cluster surveys, combined with spatial power spectrum [${P}_{c}(k)$] same clusters, can place significant constraints on evolution dark energy equation state, $w=w(a)$. evaluate expected errors ${w}_{a}=\ensuremath{-}dw/da$ other cosmological parameters using a Fisher matrix approach, simultaneously including structure our analysis. study three different types forthcoming surveys will...
We apply the technique of parameter splitting to existing cosmological data sets, check for a generic failure dark energy models. Given parameter, such as density ${\ensuremath{\Omega}}_{\ensuremath{\Lambda}}$ or equation state $w$, we split it into two meta-parameters with one controlling geometrical distances, and other growth structure. Observational spanning Type Ia Supernovae, cosmic microwave background (CMB), galaxy clustering, weak gravitational lensing statistics are fit without...
The interplay between electron-electron interactions and the honeycomb topology is expected to produce exotic quantum phenomena find applications in advanced devices. Semiconductor-based artificial graphene (AG) an ideal system for these studies that combines high-mobility electron gases with AG topology. However, date, low-disorder conditions reveal of interaction symmetry have not been achieved. Here, we report creation preserves near-perfection pristine layer by fabricating small period...
We propose to use a simple observable, the fractional area of "hot spots" in weak gravitational lensing mass maps which are detected with high significance, determine background cosmological parameters. Because these high-convergence regions directly related physical nonlinear structures universe, they derive information mainly from regime density fluctuations. show that combination future cosmic microwave anisotropy measurements, this method can place constraints on parameters comparable...
An ultrahigh field emission current density of 10.3 mA cm − 2 was obtained from nitrogen-implanted ZnO nanowires. The sample characterized and clearly showed a nitrogen doping signal. Field properties the nanowires were considerably improved after N-implantation with lower turn-on much higher density. Removal an amorphous layer, presence nanoscale protuberances, surface-related defects found to be responsible for significantly enhanced emission. Our work is important possible applications in...
The unusual electronic properties of graphene, which are a direct consequence its two-dimensional honeycomb lattice, have attracted great deal attention in recent years. Creation artificial lattices that re-create graphene's topology, known as can facilitate the investigation graphenelike phenomena, such existence massless Dirac fermions, tunable system. In this work, authors present fabrication graphene an ultrahigh quality GaAs/AlGaAs quantum well, with lattice period small 50 nm, smallest...
Engineered honeycomb lattices, called artificial graphene (AG), are tunable platforms for the study of novel electronic states related to Dirac physics. In this work, we report achievement bands topology with period as low 40 nm on nano-patterned modulation-doped AlGaAs/GaAs quantum wells. Resonant inelastic light scattering spectra reveal peaks which interpreted combined transitions between subbands well confinement a change in AG band index. Spectra lineshapes explained by joint density...
There have long been considerable efforts to study the many-body quantum phase diagram and transitions of interacting bosonic particles in solid-state systems. The particular aim is realization identification Bose-Einstein condensation, a coherent ground state with all condensed into macroscopic ground-state wave function. authors probe photogenerated excitonic ensembles coexistence two-dimensional hole system confined GaAs double well structures electrostatically trapped by local gate...
It has been shown that in an idealized galaxy cluster survey, containing ≳10,000 clusters, statistical errors on dark energy and other cosmological parameters would be at the percent level. Furthermore, through ``self-calibration,'' describing mass-observable relation cosmology could simultaneously determined, although a loss accuracy by about order of magnitude. Here we examine alternative approach to self-calibration, which parameterized ab initio physical model is used compute theoretical...
The unusual electronic properties of graphene, which are a direct consequence its two-dimensional (2D) honeycomb lattice, have attracted great deal attention in recent years. Creation artificial lattices that recreate graphene's topology, known as can facilitate the investigation graphene-like phenomena, such existence massless Dirac fermions, tunable system. In this work, we present fabrication graphene an ultra-high quality GaAs/AlGaAs quantum well, with lattice period small 50 nm,...
Recent reports on the observation of room temperature ferromagnetism in Cu doped ZnO have been highly regarded by scientific community. There are several contradicting where some authors confirmed occurrence while others ruled it out. Even studies is reported, effect carrier type with ferromagnetic properties still unclear. To study this problem, Cu-doped (5%) single crystalline films grown Si substrates was observed. were prepared pulsed laser deposition. Hall measurements showed that...