A5100775201- Advanced Radiotherapy Techniques
- Lung Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Breast Cancer Treatment Studies
- Medical Imaging Techniques and Applications
- Glaucoma and retinal disorders
- Pleural and Pulmonary Diseases
- Esophageal Cancer Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Retinal and Macular Surgery
- Head and Neck Cancer Studies
- Intraocular Surgery and Lenses
- Organ Transplantation Techniques and Outcomes
- Hydrogen's biological and therapeutic effects
- Advances in Oncology and Radiotherapy
- Hepatocellular Carcinoma Treatment and Prognosis
- Medical Imaging and Pathology Studies
- Radiomics and Machine Learning in Medical Imaging
- Synthesis of Organic Compounds
- Natural Compound Pharmacology Studies
- Lung Cancer Treatments and Mutations
- Tissue Engineering and Regenerative Medicine
Taipei Tzu Chi Hospital
2022
National Taiwan University Hospital
2022
South China Normal University
2022
Shantou University
2011-2021
Cancer Hospital of Shantou University Medical College
2014-2021
Wenzhou Medical University
2011-2016
Southwest Hospital
2016
Army Medical University
2016
University of Nevada, Las Vegas
2015
Queen's Medical Center
2015
Abstract This study aimed to compare the post-modified radical mastectomy radiotherapy (PMRMRT) for left-sided breast cancer utilizing 3-dimensional conformal with field-in-field technique (3DCRT-FinF), 5-field intensity-modulated radiation therapy (5F-IMRT) and 2- partial arc volumetric modulated (2P-VMAT). We created 3 different PMRMRT plans each of ten consecutive patients. performed Kruskal-Wallis analysis variance (ANOVA) followed by Dunn’s-type multiple comparisons establish a...
The study aimed to appraise the dose differences between Acuros XB (AXB) and Anisotropic Analytical Algorithm (AAA) in stereotactic body radiotherapy (SBRT) treatment for lung cancer with flattening filter free (FFF) beams. Additionally, potential role of calculation grid size (CGS) on two algorithms was also investigated. SBRT plans 6X 10X FFF beams produced from CT scan data 10 patients suffering stage I were enrolled this study. Clinically acceptable AAA recalculated using AXB same...
The current prospective randomized study was designed to evaluate the safety and efficacy of combined intrapleural cisplatin OK-432 (picibanil) plus hyperthermotherapy in patients with malignant pleural effusion (MPE).A total 358 MPE due end-stage malignancies were enrolled randomly divided into two groups, A B: combination (n = 179) or without 179), respectively. Mild toxicities such as nausea, vomiting anorexia, bone marrow depression, pyrexia similar both groups.Patients Group (with...
UNC119 (uncoordinated 119 or retinal protein 4), specifically expressed in the photoreceptors retina, has recently been found to be upregulated hepatocellular carcinoma (HCC) tissues, predicting a poor prognosis. However, biological role of cancer treatment is still poorly understood. Gambogic acid (GA), major component gambogic resin, shown possess anticancer activity against multiple human cell lines. In present study, we discovered that GA was more effective inhibiting proliferation HCC...
Recellularized liver, as an approach for hepatic tissue engineering, is effective alternative to orthotopic liver transplantation end-stage failure. When compared with normal recellularized has a disparity in hepatocyte viability and function, owing the difficulty of fully simulating microenvironment liver. Although sympathetic nervous system (SNS) considered important constituent few studies have examined effect SNS on engineering. It imperative explore regulation tissue-like configuration...
Purpose To assess the performance of a simple optimisation method for improving target coverage and organ-at-risk (OAR) sparing in intensity-modulated radiotherapy (IMRT) cervical oesophageal cancer. Methods For 20 selected patients, clinically acceptable original IMRT plans (Original plans) were created, two methods adopted to improve plans: 1) base dose function (BDF)-based method, which treatment re-optimised based on plans, 2) dose-controlling structure (DCS)-based by assigning...
To investigate potential dosimetric benefits and treatment efficiency of dynamic conformal arc therapy (DCA), intensity modulated radiation (IMRT), double partial arcs Rapidarc (RA) techniques in the early-stage peripheral lung cancer using stereotactic body radiotherapy (SBRT) with flattening filter free (FFF) beams. Twenty patients were selected. For each patient, DCA, IMRT RA plans created to meet Radiation Therapy Oncology Group (RTOG) 0915 objectives 48 Gy covering 95% planning target...
To identify the predictive parameter among preoperative measurements that best predicts postoperative visual outcome in epiretinal membrane (ERM).Thirty-three consecutive patients with idiopathic unilateral ERM between 2015 and 2018 were enrolled. Nineteen healthy normal eyes selected as an independent age-matched group. Based on optical coherence tomography (OCT), we further divided into two groups: type 1, loosely attached ERM, 2, tight adherent ERM. We documented vision thickness of...
Abstract Purpose Our study aimed to improve the dosimetry of post modified radical mastectomy intensity‐modulated radiotherapy (PMRM‐IMRT) for left‐sided breast cancer patients by tailoring and minimizing PTV expansion three‐dimensionally utilizing 4D CT combined with on‐board cone beam (CBCT). Methods We enrolled a total 10 consecutive undergo PMRM‐IMRT. measured intra‐fractional CTV displacement attributed respiratory movement defining 9 points on left chest wall quantifying their using...
Purpose: To investigate the technical feasibility of SBRT dose painting using 18 F‐NaF positron emission tomography (PET) scans guidance in patients with spine oligometastases from prostate cancer. Methods: As a proof concept, six 14 oligometastatic lesions cancer who had PET/CT scan prior to treatment were retrospectively included. GTV reg was delineated according regular tumor boundary shown on PET and/or CT images; and MATV contoured based net metabolically active volume (MATV) defined by...
To compare the radiobiological response between simultaneously dose-escalated and non-escalated intensity-modulated radiation therapy (DE-IMRT NE-IMRT) for patients with upper thoracic esophageal cancer (UTEC) using evaluation.Computed tomography simulation data sets 25 pathologically diagnosed primary UTEC were used in this study. DE-IMRT plan an escalated dose of 64.8 Gy/28 fractions to gross tumor volume (GTV) involved lymph nodes from UTEC, was compared NE-IMRT 50.4 fractions....
Purpose. The consistency for predicting local control (LC) data using biophysical models stereotactic body radiotherapy (SBRT) treatment of lung cancer is unclear. This study aims to compare the results calculated from different planning data. Materials and Methods. Treatment plans were designed 17 patients diagnosed with primary non-small cell (NSCLC) 5 fraction schemes. Martel model, Ohri Tai model used predict 2-year LC value. Gucken Santiago employed estimate 3-year Results. We found...
Purpose: To compare the dosimetry of post modified radical mastectomy radiotherapy (PMRMRT) for left‐sided breast cancer using 3‐dimensional conformal (3DCRT), intensity‐modulated radiation therapy (IMRT) and volumetric modulated arc (VMAT). Methods: We created ten sets PMRMRT plans consecutive patients utilized two tangential one or supraclavicular beams in 3DCRT, a total 5 IMRT optimized partial arcs VMAT. The difference results between any three new plans, previous 3DCRT were compared...
Purpose: The Smart leaf motion calculator (SLMC) in Eclipse treatment planning system is an advanced fluence delivery modeling algorithm as it takes into account fine MLC features including inter‐leaf leakage, rounded tips, non‐uniform thickness, and the spindle cavity etc. In this study, SLMC traditional Varian LMC (VLMC) algorithms were investigated, for first time, dosimetric characteristics accuracy of sliding window (SW) IMRT. Methods: SW IMRT plans 51 cancer cases included to evaluate...
Purpose: To investigate the utility of 18 F‐choline positron emission tomography (PET) scans guidance for SBRT dose painting in patients with prostate cancer and its impact on tumor control probability (TCP) normal tissue complication (NTCP). Methods: Twenty seven localized who had PET/CT scan prior to treatment were included. A pair nested intraprostatic dominant lesion (IDL) contours (IDL suv60% IDL suv70% ) generated each patient based 60% 70% maximum uptake PET images. GTV reg was...
Abstract Purpose: Recent clinical evidence has shown that SBRT using high dose with either a single fraction or limited number of fractions can lead to excellent pain control as well local tumor in patients spine oligometastases. However, limiting factor, proximity spinal cord often precludes delivering the full prescription (PD) and/or escalating planning target volume (PTV) oligometastases, thus compromising therapeutic ratio. To investigate technical feasibility painting 18F-NaF positron...
Objective To investigate the prognostic value of lymph node status evaluated by computed tomography (CT) in cervical carcinoma treated with radical chemoradiation therapy.Methods 209 patients FIGO stage Ⅰ B-ⅣA uterine chemo radiation therapy were enrolled.Lymph was based on site,number and size respectively CT.Kaplan-Meier method used to analyze impact as well other pathoclinical factors overall survival (OS).Cox regression model explore relationship between independent OS.Results Lymph...
Objective To compare IMSure QA and MatriXX for intensity modulated radiotherapy plans,and to investigate the credibility of software.Methods Ten patients receiving were randomly chosen quality assurance plans with MatriXX.Results The overall average percentage pass points in 3％ 3 mm (98.1 ± 0.8) ％ QA,and (97.9 ±0.6)％ MatriXX(t =0.86,P ＞0.05).Conclusion can be a reliable verification tool IMRT QA. Key words: Intensity radiotherapy; Dose verification; QA;