Dongfang Wang

ORCID: 0000-0003-3449-3811
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About
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Research Areas
  • Mechanical Circulatory Support Devices
  • Cardiac Arrest and Resuscitation
  • Respiratory Support and Mechanisms
  • Cardiac Structural Anomalies and Repair
  • Congenital Heart Disease Studies
  • Schizophrenia research and treatment
  • Suicide and Self-Harm Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Bipolar Disorder and Treatment
  • Tryptophan and brain disorders
  • Cardiac Ischemia and Reperfusion
  • Ferroptosis and cancer prognosis
  • Gut microbiota and health
  • Mental Health Treatment and Access
  • Airway Management and Intubation Techniques
  • Immune cells in cancer
  • Sepsis Diagnosis and Treatment
  • Central Venous Catheters and Hemodialysis
  • Mental Health Research Topics
  • Immune Cell Function and Interaction
  • Thermal Regulation in Medicine
  • Immunotherapy and Immune Responses
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cardiac Valve Diseases and Treatments
  • Asthma and respiratory diseases

Sir Run Run Shaw Hospital
2025

Zhejiang University
2025

Technical University of Munich
2020-2025

Huazhong University of Science and Technology
1996-2025

Tongji Hospital
2022-2025

South China Normal University
2020-2025

Nanjing Agricultural University
2024-2025

University of Kentucky
2014-2025

Capital Medical University
2025

National Clinical Research Center for Digestive Diseases
2025

Pseudorabies virus (PRV) is a common pathogen in multiple animal species, particularly pigs. However, PRV infection humans rare and, to the best of our knowledge, has never been isolated from human cases before.Four acute encephalitis were confirmed as based on clinical symptoms, laboratory diagnosis, and metagenomic next-generation sequencing (mNGS). Cerebrospinal fluid (CSF) samples collected applied for isolation. Etiological genetic characteristics this isolate further determined.The...

10.1093/cid/ciaa987 article EN Clinical Infectious Diseases 2020-07-10

Metabolic side effects of antipsychotic drugs can have serious health consequences and may increase mortality. Although persons with schizophrenia often take these for a long time, their mid‐ to long‐term metabolic been studied little so far. This study aimed evaluate the 31 antipsychotics in by applying random‐effects Bayesian network meta‐analysis. We searched Cochrane Schizophrenia Group's Study‐Based Register Trials (up April 27, 2020) PubMed June 14, 2021). included published...

10.1002/wps.21036 article EN World Psychiatry 2023-01-14

Most acute phase antipsychotic drug trials in schizophrenia last only a few weeks, but patients must usually take these drugs much longer. We examined the long-term efficacy of acutely ill using network meta-analysis. searched Cochrane Schizophrenia Group register up to March 6, 2022 for randomized, blinded at least 6-month duration on all second-generation and 18 first-generation antipsychotics. The primary outcome was change overall symptoms schizophrenia; secondary outcomes were all-cause...

10.1002/wps.21089 article EN World Psychiatry 2023-05-09

Expanding the efficacy of immune checkpoint blockade (ICB) in colorectal cancer (CRC) presses for a comprehensive understanding treatment responsiveness. Here, we analyze multiple sequential single-cell samples from 22 patients undergoing PD-1 to map evolution local and systemic immunity CRC patients. In tumors, identify coordinated cellular programs exhibiting distinct response associations. Specifically, exhausted T (Tex) or tumor-reactive-like CD8+ (Ttr-like) cells are closely related...

10.1016/j.ccell.2024.06.009 article EN cc-by-nc Cancer Cell 2024-07-01

We are developing a high performance double lumen cannula (DLC) for minimally invasive, ambulatory and percutaneous paracorporeal artificial lung (PAL). The Wang-Zwische (W-Z) DLC was designed insertion into the Internal Jugular (IJ) vein with drainage open to both superior vena cava (SVC) inferior (IVC) maximizing venous drainage. A separate collapsible but nondistensible membrane infusion right atrium (RA) achieves minimal recirculation allowing total gas exchange. W-Z prototypes made by...

10.1097/mat.0b013e31818c69ab article EN ASAIO Journal 2008-11-01

Correct placement of the Avalon Elite Bicaval Dual Lumen catheter (Avalon Laboratories, LLC, CA) for single-site venovenous extracorporeal membrane oxygenation (VV ECMO) is safe using image guidance. Using this technique, 26 27 patients (96%) had uneventful cannula in right internal jugular vein. One patient a superior vena cava injury during serial dilation, and another required repositioning improved flows. We recommend both fluoroscopy transesophageal echocardiogram (TEE) training...

10.1097/mat.0b013e3182155fee article EN ASAIO Journal 2011-04-15

Background: Current psychotic-like experiences (PLEs) are prevalent among adolescents. However, epidemiological data on the prevalence rate of current PLEs college students and its clinical correlates scarce limited. To address this study gap, aimed to investigate Chinese students. Methods: A cross-sectional was designed with a sample 18,578 in China. Each participant completed survey social-demographic characteristics variables, PLEs, sleep disturbance, depression, anxiety, suicidal...

10.2147/prbm.s451889 article EN cc-by-nc Psychology Research and Behavior Management 2024-02-01

Immune checkpoint blockade (ICB) improved clinical outcomes in renal and bladder cancer patients, but the response rates remain limited especially metastatic disease. While STAT3 transcription factor is well-known master regulator of tumor immune evasion, little known about role resistance or cancers to immunotherapy.

10.3389/fimmu.2023.1274781 article EN cc-by Frontiers in Immunology 2024-01-08

The doctor–patient relationship (DPR) is essential in the process of medical consultations and treatments. Poor DPR may lead to poor outcomes, violence against doctors, a negative perception healthcare system. Little known about how affected during this novel coronavirus disease 2019 (COVID-19) pandemic. This cross-sectional study aimed explore COVID-19 There were 1,903 participants China (95% response rate) who recruited pandemic online via convenience snowball sampling. Several...

10.3389/fpubh.2021.646486 article EN cc-by Frontiers in Public Health 2021-07-06

Chitosan-modified poly(lactic-co-glycolic acid) nanoparticles (CHI/PLGA NPs) loaded with 7-ethyl-10-hydroxycamptothecin (SN-38), named CHI/PLGA/SN-38 NPs, were successfully prepared using an oil-in-water (O/W) solvent evaporation method. The physicochemical properties of the novel NPs characterized by DLS, Zeta potential, SEM, DSC, XRD, and FTIR. encapsulation efficiency drug loading content 71.83 (±2.77)% 6.79 (±0.26)%, respectively. In vitro release in simulated gastric juice was lower...

10.1088/0957-4484/24/24/245101 article EN Nanotechnology 2013-05-23

Abstract Objective To assess the quality of doctor-patient relationship (DPR) in China and possible influencing factors during COVID-19 period from patient’s perspective. Methods An online survey was carried out nationwide March 12, 2020 to 30, via a convenience sampling strategy. Patients who met inclusion criteria were invited complete questionnaire regarding DPR, including sociodemographic information, Patient-Doctor Relationship Questionnaire (PDRQ-9), for DPR pandemic. Results A total...

10.1186/s12875-021-01600-y article EN cc-by BMC Family Practice 2021-12-01
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