A5063461841- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Contact Dermatitis and Allergies
- Insect Utilization and Effects
- Identification and Quantification in Food
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Asthma and respiratory diseases
- Protein Hydrolysis and Bioactive Peptides
- Animal and Plant Science Education
- Immunotherapy and Immune Responses
- Advanced Drug Delivery Systems
- Mast cells and histamine
- RNA Interference and Gene Delivery
- Animal Genetics and Reproduction
- Invertebrate Immune Response Mechanisms
- Meat and Animal Product Quality
James Cook University
2019-2024
Royal Children's Hospital
2020-2024
Murdoch Children's Research Institute
2019-2024
Australian Institute of Tropical Health and Medicine
2019-2024
ENT and Allergy
2023
Abstract Background Diagnostic tests for fish allergy are hampered by the large number of under‐investigated species. Four salmon allergens well‐characterized and registered with WHO/IUIS while no catfish have been described so far. In 2008, freshwater‐cultured production surpassed that salmon, globally most‐cultured marine We aimed to identify, quantify, compare all IgE‐binding proteins in catfish. Methods Seventy‐seven pediatric patients clinically confirmed underwent skin prick The...
Understanding and predicting an individual's clinical cross-reactivity to related allergens is a key better management, treatment progression of novel therapeutics for food allergy. In allergy, observed in patients reacting unexpected allergen sources containing the same allergenic protein or antibody binding patches (epitopes), often resulting severe allergic reactions. Shellfish allergy affects up 2% world population persists life most patients. The diagnosis shellfish however challenging...
Insects have been consumed by people for millennia and recently proposed as a complementary, sustainable source of protein to feed the world's growing population. crustaceans both belong arthropod family. Crustacean (shellfish) allergies are common potentially severe; hence, cross-reactivity immune system with insect proteins is potential health concern. Herein, LC-MS/MS was used explore proteome whole, roasted whole powdered cricket products. Eight extraction protocols were compared using...
Abstract Background Major fish allergens, including parvalbumin (PV), are heat stable and can withstand extensive cooking processes. Thus, the management of allergy generally relies on complete avoidance. Fish‐allergic patients may be advised to consume canned fish, as some fish‐allergic individuals have reported tolerance fish. However, safety consuming has not been evaluated with comprehensive immunological molecular analysis products. Methods We characterized in vitro immunoreactivity...
Abstract Background Clinical cross‐reactivity between bony fish, cartilaginous frog, and chicken muscle has previously been demonstrated in fish‐allergic patients. In indicative studies, two reports of anaphylaxis following the consumption crocodile meat IgE‐cross‐binding were linked to major fish allergen parvalbumin (PV). This study investigates IgE‐binding proteins with a focus on PV their clinical relevance. Methods Proteins extracted from tissue crocodile, three fish. A cohort pediatric...
Edible insect proteins are increasingly introduced as an alternative sustainable food source to address the world's need feed growing population. Tropomyosin is main allergen; however, additional potential allergens not well characterized and impact of extraction procedures on immunological reactivity unknown.
Shellfish allergy affects 2% of the world's population and persists for life in most patients. The diagnosis shellfish allergy, particular shrimp, is challenging due to similarity allergenic proteins from other invertebrates. Despite clinical importance immunological cross-reactivity among species between invertebrates such as dust mites, underlying molecular basis not well understood. Here we mine complete transcriptome five frequently consumed shrimp identify compare allergens with all...
The Pacific oyster is a commercially important mollusc and, in contrast to most other shellfish species, frequently consumed without prior heat treatment. Oysters are rich many nutrients but can also cause food allergy. Knowledge of their allergens and cross-reactivity remains very limited. These limitations make an optimal diagnosis allergy difficult, particular the (Crassostrea gigas), cultivated species worldwide. This study aimed characterise IgE sensitisation profiles 21...
Exploration of important insect proteins — including allergens and proteomes can be limited by protein extraction buffer selection the complexity proteome. Herein, LC-MS/MS-based proteomics experiments were used to assess efficiencies for a suite buffers effect ingredient processing on proteome allergen detection. Discovery revealed that SDS-based yields maximum number groups from three types BSF samples. Bioinformatic analysis composition could influence Upon applying multi-level filtering...
Shellfish allergy affects ~2.5% of the global population and is a type I immune response resulting from exposure to crustacean and/or molluscan proteins. The Australian Redclaw crayfish (Cherax quadricarinatus) freshwater species endemic farmed in northern Australia becoming an aquaculture interest globally. Despite being consumed as food, allergenic proteins redclaw have not been identified or characterised. In addition, different body parts are often consumed, it conceivable that tissues...
Due to the widespread use of shellfish ingredients in food products, accurate labelling is urgently needed for consumers with allergies. Most crustacean allergen detection systems target immunorecognition allergenic protein tropomyosin. However, this mode may be affected by an origin-dependent composition. This study determined if geographic location capture, or aquaculture, influenced profiles Black Tiger Shrimp (Penaeus monodon), one most farmed and consumed shrimp species worldwide....
Abstract Shellfish allergy affects up to 2% of the world’s population and persists for life in most patients. The diagnosis a shellfish allergy, particular shrimp, is however often challenging due similarity allergenic proteins other invertebrates. Despite clinical importance, complete allergen repertoire allergy-causing shrimps remains unclear. Here we mine transcriptome five frequently consumed shrimp species identify compare allergens with all known sources. transcriptomes were assembled...
Similar IgE Binding Patterns in Gulf of Mexico and Southeast Asian Shrimp Species US Allergic PatientsSara Anvari1,2*, Shea Brunner1,2*, Karen Tuano1,2, Brenda Bin Su1,2, Shaymaviswanathan Karnaneed3, Andreas L. Lopata3, Carla M. Davis1,21Baylor College Medicine, Texas Children’s Hospital, Department Pediatrics, Section Immunology, Allergy Retrovirology, Houston, Texas2Baylor William T. Shearer Center for Human Immunobiology, Texas3James Cook University, Australian Institute Tropical Health...