- Meningioma and schwannoma management
- Pituitary Gland Disorders and Treatments
- Head and Neck Surgical Oncology
- Glioma Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Adrenal and Paraganglionic Tumors
- Delphi Technique in Research
- Myasthenia Gravis and Thymoma
- Spinal Fractures and Fixation Techniques
- Pharmacological Effects and Toxicity Studies
- Hormonal and reproductive studies
- Migraine and Headache Studies
- Obstructive Sleep Apnea Research
- Opioid Use Disorder Treatment
- Ophthalmology and Eye Disorders
- Intraoperative Neuromonitoring and Anesthetic Effects
- Clinical practice guidelines implementation
- Neurosurgical Procedures and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Brain Metastases and Treatment
- Retinal Diseases and Treatments
- Scoliosis diagnosis and treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Family Support in Illness
- Aortic aneurysm repair treatments
Leiden University Medical Center
2016-2025
Leiden University
2020-2024
Medisch Centrum Haaglanden
2016-2024
Berman Group (Czechia)
2021
Islamic Azad University of Najafabad
2021
The Sherwood Institute
2021
Creative Commons
2021
Amsterdam UMC Location Vrije Universiteit Amsterdam
2016
Background The extent to which people implement government-issued protective measures is critical in preventing further spread of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2. Our study aimed describe the public belief effectiveness measures, reported implementation these and identify communication channels used acquire information on COVID-19 European countries during early stage pandemic. Methods findings An online survey available multiple languages was disseminated starting...
Objectives To assess the difference in completeness of reporting and methodological conduct published prediction models before after publication Transparent Reporting a multivariable model for Individual Prognosis Or Diagnosis (TRIPOD) statement. Methods In seven general medicine journals with highest impact factor, we compared quality methodology studies between 2012 2014 (pre-TRIPOD) 2016 2017 (post-TRIPOD). For articles post-TRIPOD period, examined whether there was improved (1) citing...
Abstract Enhanced sensitivity to light (photophobia) and patterns is common in migraine can be regarded as visual allodynia. We aimed develop validate a questionnaire easily quantify large populations, assess compare allodynia across different subtypes states. developed the Leiden Visual Sensitivity Scale (L-VISS), 9-item scale (score range 0-36 points), based on literature patient interviews, examined its construct validity. Furthermore, we assessed ictal interictal episodic with (n = 67)...
Pituitary tumors may have a considerable impact on patients' functional status, including paid employment, yet research in this area is sparse.To describe work disability and its determinants patients treated for pituitary tumor.Cross-sectional study tumor the working age (18-65 years), who completed five validated questionnaires assessing [Short Form-Health Labour Questionnaire, Work Role Functioning Questionnaire 2.0 (WRFQ)], health-related quality of life (HRQoL) utility (Short Form-36,...
Abstract Introduction Meningioma is a heterogeneous disease and patients may suffer from long-term tumor- treatment-related sequelae. To help identify at risk for these late effects, we first assessed variables associated with impaired health-related quality of life (HRQoL) neurocognitive function on group level (i.e. determinants). Next, prediction models were developed to predict the or HRQoL impairment individual patient-level. Methods Secondary data analysis cross-sectional multicenter...
Abstract Background Core Outcome Sets (COS) define the minimum outcomes that should be measured and reported in all clinical trials for a specific health condition or area. The aim was to develop two COS intracranial meningioma used future studies: COSMIC: Intervention effectiveness Observation studies of incidental/untreated meningioma. Methods A study advisory group formed with representation from international stakeholder groups: EORTC BTG, ICOM, EANO, SNO, RANO-PRO, BNOS, SBNS, BIMS,...
Although widely advocated, applying Value Based Health Care (VBHC) in clinical practice is challenging. This study describes VBHC-based perioperative outcomes for patients with pituitary tumors up to 6 months postoperatively.A total of 103 adult undergoing surgery were prospectively followed. Outcomes categorized according the framework VHBC included survival, degree resection, endocrine remission, visual outcome (including self-perceived functioning), recovery function, disease burden and...
Abstract BACKGROUND Many intracranial meningioma patients have an impaired health-related quality of life (HRQoL) and neurocognitive functioning up to 4 yr after intervention. OBJECTIVE To assess the long-term (≥5 yr) disease burden patients. METHODS In this multicenter cross-sectional study, ≥5 intervention (including active magnetic resonance imaging (MRI) surveillance) were included assessed for HRQoL (Short-Form Health Survey 36), (neuropsychological assessment), anxiety depression...
Meningioma is the most common primary intracranial tumour in adults. The majority are non-malignant, but a proportion behave more aggressively. Incidental/minimally symptomatic meningioma often managed by serial imaging. Symptomatic meningioma, those that threaten neurovascular structures, or demonstrate radiological growth, usually resected as first-line management strategy. For patients poor clinical condition, with inoperable, residual recurrent disease, radiotherapy used adjuvant...
OBJECTIVE Patients with skull base meningioma (SBM) often require complex surgery around critical neurovascular structures, placing them at high risk of poor health-related quality life (HRQOL) and possibly neurocognitive dysfunction. As the survival patients is near normal, long-term HRQOL outcomes are important to evaluate, including evaluation impact specific tumor location treatment modalities on these outcomes. METHODS In this multicenter cross-sectional study 5 years or more after...