Ping Jiang

ORCID: 0000-0003-2401-7643
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Liver Diseases and Immunity
  • Microplastics and Plastic Pollution
  • Drug Transport and Resistance Mechanisms
  • Asthma and respiratory diseases
  • Advanced biosensing and bioanalysis techniques
  • Gut microbiota and health
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Pediatric Hepatobiliary Diseases and Treatments
  • Environmental Toxicology and Ecotoxicology
  • Marine Biology and Environmental Chemistry
  • Neurological Disease Mechanisms and Treatments
  • Cyclone Separators and Fluid Dynamics
  • Graphene and Nanomaterials Applications
  • IL-33, ST2, and ILC Pathways
  • Glutathione Transferases and Polymorphisms
  • Mercury impact and mitigation studies
  • Diet and metabolism studies
  • Cholesterol and Lipid Metabolism
  • Advanced Computing and Algorithms
  • Radical Photochemical Reactions
  • Organometallic Compounds Synthesis and Characterization
  • Acute Ischemic Stroke Management
  • Neurological Disorders and Treatments
  • IoT-based Smart Home Systems
  • Vehicle emissions and performance

Nanjing Medical University
2010-2025

Anhui University
2024

China-Japan Friendship Hospital
2024

Nanjing Forestry University
2024

Shenzhen Institutes of Advanced Technology
2024

Chinese Academy of Sciences
2024

Songjiang District Central Hospital
2016-2017

Jiangsu University
2011

The ubiquitous presence of Microplastics (MPs) in various environments documented recent years has recently raised significant concerns about their toxic effects. While macrophages serve as the first line defense against substances and pathogens, impact mechanisms microplastics on these immune cells remain unclear. This study aims to explore whether MPs induce macrophage apoptosis through promotion reactive oxygen species (ROS) generation alterations metabolic profiles. viability RAW264.7...

10.1016/j.ecoenv.2024.115970 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2024-01-12

Microplastics (MPs) and tributyltin (TBT) are both potential environmental pollutants that enter organisms through the food chain affect bodily functions. However, effects mechanisms of MPs TBT exposure (especially co-exposure pollutants) on mammals remain unclear. In this study, Ф5 μm (5MP) was administered alone or in combination with to investigate health risk oral mice. All three treatments induced inflammation liver, altered gut microbiota composition disturbed fecal bile acids...

10.1016/j.ecoenv.2021.112345 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-05-18

Recently, both trivalent chromium Cr (III) and hexavalent (VI) have been reported to produce neurotoxicity. However, the underlying mechanisms of neurotoxicity caused by different chemical valence remain unclear. The purpose this study was investigate mechanism induced exposure with states based on metabolic disturbance in zebrafish larvae. Zebrafish embryos were exposed 1 mg/L for 120 hpf respectively. related indexes neural development observed stereoscope behavior analysis system. 8OH-dG...

10.1016/j.ecoenv.2021.112983 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-11-13

A visible-light-mediated catalyst- and additive-free method for radical ring-opening fluorosulfonylation of methylenecyclobutanols is reported. Sulfuryl chlorofluoride acts as a FSO

10.1021/acs.orglett.4c01989 article EN Organic Letters 2024-06-24

Sulforaphane (SFN) is a promising phytochemical with wide range of antitumor activities. A comprehensive understanding the effects SFN on breast cancer based metabolome and microbiome limited. Thus, we treated MCF-7 cell-transplanted nude mice 50 mg/kg SFN. inhibits cell proliferation. increased levels sulfate-related metabolites glutathione-related decreased tryptophan methyl-purine in urinary metabolic profile. indirectly affected activation aryl hydrocarbon receptor by metabolism. The...

10.1002/fsn3.3168 article EN cc-by Food Science & Nutrition 2023-03-31

Abstract In recent years, chromium (Cr) has been found to induce neurotoxicity. However, the underlying mechanism remains unclear. This study aimed investigate effects of exposure on metabolome and microbiome that may contribute neurotoxicity in juvenile zebrafish. Zebrafish embryos were exposed 1 mg/L Cr (III) (VI) for 7 days, respectively. Swimming distance locomotor behavior was decreased, acetylcholinesterase activity reduced Cr‐exposed groups. Total cholesterol levels decreased The...

10.1002/jat.4440 article EN Journal of Applied Toxicology 2023-02-02

Primary sclerosing cholangitis (PSC) is a chronic cholestatic disease characterized by inflammation and fibrosis of the bile ducts. Cholestasis may lead to hepatic fibrosis, amelioration cholestasis allow recovery from inflammatory fibrotic pathological damage. Prevotella copri (P. copri) interventions have been reported significantly improve liver in 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)-induced PSC mouse models. Even though P. treatment alone cannot bring about DDC-induced...

10.3390/ijms241311010 article EN International Journal of Molecular Sciences 2023-07-02

Understanding the transport mechanism of peptide Asn-Cys-Trp (NCW) is crucial to improving its intestinal absorption and bioavailability. This study investigated NCW through Caco-2 cell monolayers interaction with DPPC bilayers. Results revealed that after a 3 h incubation, Papp (AP-BL) (BL-AP) values at concentration 5 mmol/L were (22.24 ± 4.52) × 10–7 (6.63 2.31) cm/s, respectively, rates 1.59 0.32 0.62 0.20%, indicating moderate absorption. was found be transported via PepT1 paracellular...

10.1021/acs.jafc.4c00155 article EN Journal of Agricultural and Food Chemistry 2024-04-19

Background and objectives The oral gut microbiota play significant roles in childhood asthma pathogenesis. However, the communication dynamics pathogenic mechanisms by which influence disease development remain incompletely understood. This study investigated potential oral-originated microbiota, specifically Prevotella genus, may contribute to etiology. Methods Oral swab fecal samples from 30 asthmatic children healthy controls were collected. Microbiome composition was characterized using...

10.3389/fmicb.2024.1400079 article EN cc-by Frontiers in Microbiology 2024-05-28

In this article, a dual-signal sensor for the fluorescence and colorimetric detection of glyphosate (Gly) is developed based on DNAzyme-mediated click chemistry DNAzyme-regulated CeO2 peroxidase-like activity. DNAzyme can bind to Cu+, triggering reaction between 3-Azido-7-hydroxycoumarin (AHC) 3-ethyn-1-ol (BOL), thus generating strong signal at 475 nm. Due coordination Gly Cu2+, amount reduced Cu+ decreases, resulting in weakening fluorescence. addition, inhibit catalytic site enzyme...

10.1021/acs.jafc.4c12499 article EN Journal of Agricultural and Food Chemistry 2025-03-17

Tributyltin (TBT), an environmental pollutant widely used in antifouling coatings, can cause multiple-organ toxicity and gut microbiome dysbiosis organisms, even changes the host metabolomic profiles. However, little is known about underlying effects links of TBT-induced metabolic dysbiosis. In this study, rats were exposed to TBT at a dose 100 μg kg-1 body weight (BW) for 38 days, followed by multi-omics analysis, including microbiome, metabolomics, metallomics. Results showed that exposure...

10.1039/d0ra07502g article EN cc-by-nc RSC Advances 2020-01-01

In order to investigate the influence of combustion chamber geometry on spray and characteristics in diesel engine, universal CFD software STAR-CD is applied simulate processes three different types chambers engine. The effect in–cylinder air motion, temperature field exhaust emissions are researched this paper. Comparing with experimental results, calculation models proved be validity. results show that differences shape change characteristic flow cylinder, which affects formation mixed gas...

10.4028/www.scientific.net/amr.199-200.193 article EN Advanced materials research 2011-02-01

Abstract Background: Epidemiological studies have showed that PAHs may exert its adverse effects on childhood asthma. However, the underlying molecular mechanism remains to be fully elucidated. This study aimed investigate this process in view of metabolic pathway, especially one carbon metabolism and tryptophan metabolism. Methods: Fifty asthmatic children fifty control subjects were recruited study. Serum IgE IL-17A was detected by ELISA assay. concentrations measured GC-MS. One...

10.21203/rs.3.rs-1470556/v1 preprint EN cc-by Research Square (Research Square) 2022-04-11

Objective To explore the relations of nicotinamide adenine dinucleotide phosphate(NAD[P]H)oxidase p22phox C242T gene polymorphism with hyperlipidemia and cerebral infarction. Methods A case-control association study containing 207 patients(collected from Physical Examination Center March 2014 to 2015), 185 infarction Department Neurology 2015)and 183 controls(collected 2015)was carried out. The genetypes allele frequency were compared; clinical data, lipoprotein oxidation level...

10.3760/cma.j.issn.1671-8925.2016.02.011 article EN Chinese Journal of Neuromedicine 2016-02-15

Objective To investigate the effects of hydrochloride fasudil on inflammation and secondary brain injury in rats after intracerebral hemorrhage (ICH). Methods One hundred seventeen male Wistar were randomly divided into normal group (n=9), sham-operated (n=36), ICH (n=36) treatment (ICH/HF, n=36). was caused by injecting non-anticoagulant autologous arterial blood right caudate nucleus, 3 mg HF dissolved 2 mL 0.9% saline solution administrated intraperitioneally once daily (12...

10.3760/cma.j.issn.1671-8925.2017.11.001 article EN Chinese Journal of Neuromedicine 2017-11-15
Coming Soon ...