A A Савин

ORCID: 0000-0003-2413-7311
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About
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Research Areas
  • Neurological Disorders and Treatments
  • Acute Ischemic Stroke Management
  • Medical and Biological Ozone Research
  • Neurological Disease Mechanisms and Treatments
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Peripheral Neuropathies and Disorders
  • Pulmonary Hypertension Research and Treatments
  • S100 Proteins and Annexins
  • Long-Term Effects of COVID-19
  • Laser Applications in Dentistry and Medicine
  • Cardiovascular Health and Disease Prevention
  • Cardiac Arrest and Resuscitation
  • Phagocytosis and Immune Regulation
  • Restless Legs Syndrome Research
  • Microscopic Colitis
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Biochemical effects in animals
  • Alcohol Consumption and Health Effects
  • Bone health and treatments
  • Shoulder and Clavicle Injuries
  • Genetic and Kidney Cyst Diseases
  • Fetal and Pediatric Neurological Disorders
  • Effects of Vibration on Health
  • Muscle and Compartmental Disorders
  • Lymphoma Diagnosis and Treatment

McGill University
2024

Moscow State University of Medicine and Dentistry
1990-2024

Ministry of Health of the Russian Federation
2018-2024

Grigore T. Popa University of Medicine and Pharmacy
2017

Objective. To study the effect of new coronavirus infection COVID-19 on course and prognosis tuberculous meningoencephalitis in HIV-infected patients. Material methods. The main group included 46 patients with human immunodeficiency virus (HIV) who were infected a infection. comparison 52 HIV had no history All underwent laboratory tests for infectious diseases (including analysis cerebrospinal fluid (CSF)), parameters hemostasis system, CT lungs brain as part an inpatient examination....

10.17116/jnevro202512503133 article EN S S Korsakov Journal of Neurology and Psychiatry 2025-04-08

The Fas system can promote several biological effects due to their activation after ischemic stroke: apoptosis, inflammation, proliferation, differentiation. interacts with adapter proteins activating a number of signaling pathways, including MAPK, NFKB, JNK, ERK, phosphorylation cytoskeletal proteins, and caspase-dependent apoptosis. expressed by neuronal progenitor cells from the subventricular zone does not induce apoptosis in healthy adult humans. During motion differentiation these...

10.17116/jnevro2016116323-8 article RU S S Korsakov Journal of Neurology and Psychiatry 2016-01-01

To assess the impact of quasi-monochromatic partially coherent infra-red radiation on dynamics recovery affected joint and hemostatic system in patients with post-stroke arthropathy shoulder joint.Fifty-five early, late residual period ischemic stroke were studied. Group I consisted 27 who underwent 10 sessions photomatrix therapy (wavelength 600 nm) joint, lasting for minutes. In group II (n=28), duration was 20 Patients comparison (n=20) did not receive therapy.The results pointed to a...

10.17116/jnevro20161166120-24 article RU S S Korsakov Journal of Neurology and Psychiatry 2016-01-01

To analyze the histological features of changes in brain tissue after ischemic stroke.Brain samples obtained autopsy from 9 people died as a result left middle cerebral artery stroke 3 to 7 days admission were studied. Tissue taken areas brain: 1) contiguous necrotic damage site zone, 2) 5-10 cm distant previous one, 3) contralateral hemisphere zone symmetrical site. Samples Nissl and hematoxylin-eosin stained. Detection p53 protein, NSE, GFAP was performed by indirect immunoperoxidase...

10.17116/jnevro20171173266-70 article RU S S Korsakov Journal of Neurology and Psychiatry 2017-01-01

Mammography is one of the most common screening test in female population. In addition to identifying breast cancer, vascular calcification clearly visualized on mammogram, which associated with an increased risk cardiovascular disease, atherosclerosis, and a number other chronic non-communicable diseases. The article presents case report postmenopausal woman artery osteoporosis. Identification women at non-cancer diseases significantly expands prospects using mammography for screening.

10.15829/1728-8800-2020-2574 article EN cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2020-09-05

A case report of central pontine and extrapontine myelinolysis in the combination with spinal cord damage is presented. The authors analyze literature data on this problem discuss pathogenesis diagnostic issues myelinolysis.Приведено наблюдение больного с туберкулезом легких понтинным и экстрапонтинным миелинолизом в сочетании поражением спинного мозга. Анализируются данные литературы, посвященные этой проблеме. Обсуждаются вопросы патогенеза диагностики миелинолиза.

10.17116/jnevro201711721117-123 article RU S S Korsakov Journal of Neurology and Psychiatry 2017-01-01

In response to ischemic stroke (IS) a natural activation of the stress-realizing system occurs. The features this influence outcome acute period and prognosis recovery can be adjusted. At same time, role in pathogenesis IS is still unexplored. Objective : investigate effect peripheral blood cortisol concentration on regulation apoptosis neurons cerebral cortex phase IS. Material methods . A prospective clinical pathological study was performed. It included 9 patients with left middle artery...

10.14412/2074-2711-2024-1-49-56 article EN cc-by Neurology neuropsychiatry Psychosomatics 2024-02-20

10.1016/s1155-195x(23)47754-7 article FR Encyclopédie médico-chirurgicale. Pneumologie 2024-04-01

10.1016/s1155-195x(24)45836-2 article FR Encyclopédie médico-chirurgicale. Pneumologie 2024-10-01

The objective of the present study was to identify clinical and pathomorphological changes in internal organs for elucidation cause death associated with various forms alcoholic intoxication (chronic intoxication, poisoning surrogate alcohols, etc.). analysis conditions resulting from alcohol abuse has demonstrated that principal pathology underlying fatal outcome is complemented by a variety non-lethal somatic disorders aggravating patients' condition enhancing its severity. clinicians are...

10.17116/sudmed2018613-14 article RU Forensic Medical Expertise 2018-01-01

Aim. To investigate the health-related quality of life among patients with hand-arm vibration syndrome in Kabardino-Balkar Republic. Methods. The study included 198 aged 36-65 years. (HRQoL) was assessed using SF-36 questionnaire before and after recreation treatment. Patients were divided to 3 groups according disease severity: stage 1 - 54 (27.3%) patients, 2 75 (37.9%) 69 (34.8%) patients. Results. Marked decrease all HRQoL parameters measured by observed at baseline. After treatment...

10.17816/kmj1954 article EN cc-by-nc-sa Kazan medical journal 2013-12-15

The further development of new method phototherapy based on use light-emitting diodes (LED) arrays has been presented. LEDs array distribution is side cylindrical surface, covering pathology region, was used for treatment group patients with an affected peripheral nervous system. main consisted humeral plexopathy - one possible neurological manifestation postmastectomic syndrome as result breast cancer radical treatment. This disease accompanied also by some other system diseases: diabetic...

10.1117/12.427781 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2001-05-21

OBJECTIVE To identify correlations between parameters of vascular stiffness and characteristics the clinical course acute cerebrovascular accident (stroke). MATERIAL AND METHODS Two hundred seven patients with stroke (mean age 64.6±10.9 years; 115 men) treated in a neurological department «Municipal Clinical Hospital Br. Bakhrushins Health Care Department Moscow» were studied. All underwent standard clinical-instrumental examination, including assessment arterial by sphygmography. Analysis...

10.17116/jnevro202012012216 article EN S S Korsakov Journal of Neurology and Psychiatry 2020-01-01

The objective of the present work was to study pathological changes in various organs and tanatogenesis associated with Mallory-Weiss syndrome making use forensic medical clinical materials. It shown that main cause unrestrained vomiting resulting from alcoholic intoxication leading perfusive bleeding is not only direct action ethanol surrogate alcohol on gastroesophageal mucosa induced thrombocytopenia. Another may be brain oedema subsequent cerebral herniation irritation pseudobulbar...

10.17116/sudmed201558122-25 article RU Forensic Medical Expertise 2015-01-01

The article reports on the rarest case of Guillain-Barré syndrome in form acute motor-sensory polyneuropathy a female patient with tuberculous meningitis, disseminated pulmonary tuberculosis, and pleurisy. In neurological status at exit from coma, was diagnosed tetraplegia, bulbar syndrome, respiratory disorders. Further, within week, pronounced muscle atrophy appeared. Active etiotropic, pathogenetic therapy, including plasmapheresis, gave dramatic effect significant improvement condition...

10.17116/jnevro2023123081129 article RU S S Korsakov Journal of Neurology and Psychiatry 2023-01-01

Background: Ulcerative colitis (UC) is a lifelong systemic multifactorial disease with negative impact on health-related quality of life (HRQoL). Restless Legs Syndrome (RLS) as an extraintestinal manifestation UC not very common. This association has been investigated in small number studies but results remain controversial. The primary aim the current study was to investigate prevalence and between RLS UC. Methods: 120 subjects (man/female: 67/53, age at diagnosis: 39.3 years, SD: 16.2)...

10.1093/ecco-jcc/jjx002.328 article EN Journal of Crohn s and Colitis 2017-01-26

Background: In patients with inflammatory bowel disease in remission the de – escalating treatment strategy is controversial. Because of safety and economic issues, stopping one therapy ulcerative colitis (UC) might be an option, but there are no recommendation regarding this question. The aim our study was to assess risk factors for relapse UC at least 6 months combination (anti-TNF azathioprine AZA) after AZA discontinuation. Methods: Between January 2013 June 2015 we prospective enrolled...

10.1093/ecco-jcc/jjx002.513 article EN Journal of Crohn s and Colitis 2017-01-26

The article presents the results of using home-produced photomatrix led devices red glow in rehabilitation patients with post-stroke arthropathy. study involved 88 late and residual periods ischemic stroke. Patients were selected into 1st 2nd main group matched for age number patients. included recovery period stroke, 2 nd one - period. control was formed by who had not undergone therapy. groups underwent a 10-sessions course therapy on affected joint. obtained indicated significant decrease...

10.21626/vestnik/2017-4/04 article EN cc-by Человек и его здоровье 2017-01-01

Introduction. Neuronal cell death (apoptosis) is not only a direct consequence of cerebral infarction, but also crucial pathogenetic link ischemic injury. Nevertheless, the role apoptotic markers in prediction functional outcome acute phase stroke (IS) has been established. Objective. To determine possibility predicting earliest period after its development by measuring thes FasL and sFas concentrations peripheral blood. Materials methods. One hundred fifty-five individuals underwent...

10.18454/acen.2017.1.6151 article EN Annals of Clinical and Experimental Neurology 2017-05-12
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