A5089421451- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Agricultural Productivity and Crop Improvement
- Cardiovascular Function and Risk Factors
- Neurological Disorders and Treatments
- Healthcare Systems and Public Health
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- Agriculture and Biological Studies
- Biomarkers in Disease Mechanisms
- Wheat and Barley Genetics and Pathology
- Chromosomal and Genetic Variations
- Cardiovascular and exercise physiology
- GDF15 and Related Biomarkers
- Viral Infections and Immunology Research
- Heart Failure Treatment and Management
- Hypertrophic osteoarthropathy and related conditions
- Transcranial Magnetic Stimulation Studies
- Animal Nutrition and Health
- Male Breast Health Studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Social and Behavioral Studies
- Lipoproteins and Cardiovascular Health
- Acute Ischemic Stroke Management
Moscow State University of Medicine and Dentistry
2010-2023
Ministry of Health of the Russian Federation
2016-2019
All-Russian Horticultural Institute for Breeding, Agrotechnology and Nursery
2019
Federal Almazov North-West Medical Research Centre
2019
Russian Academy of Sciences
2010-2016
Russian Scientific Center of Radiology and Surgical Technologies
2014
Saint - Petersburg State Chemical Pharmaceutical Academy
2010-2013
Charing Cross Hospital
2011
Zhejiang University Medical College Affiliated Stomatological Hospital
2008
Russian State Agrarian University - Moscow Timiryazev Agricultural Academy
2000
Recently, there was plenty studies published on the arterial stiffness assessment, and importance of this proved as an independent prediction parameter, together with standard cardiovascular risk factors. In current document, we collect structure available clinical scientific data from abroad Russian studies. The aim publication is need to bring a reader demanded in practice ways wall information about conditions when it important restrictions, issues remaining unresolved.
Previous experimental studies have suggested a beneficial effect of extracorporeal shock wave therapy (ESWT) in patients with ischemic heart failure. Twenty‐four failure and left ventricular ejection fraction (LVEF) <40% received ESWT addition to their stable treatment. was performed 9 sessions 100 shocks per spot viable segments detected by dobutamine stress echocardiography. Patients were evaluated at baseline 3 6 months after ESWT. Tc‐99m MIBI single photon emission computed tomography...
This study was undertaken to evaluate possible antiallergic effects of an extract pigments from green sea urchin (<i>Strongylocentrotus droebachiensis</i>) shells. Effects were studied on animal models – guinea pig ileum contraction, rabbit eyes allergic conjunctivitis, and local skin irritation. The significantly reduced, in a dose-dependent manner, the histamine-induced contractions isolated with ID<sub>50</sub> = 1.2 µg/mL (in equivalents spinochrome B), had inhibitory effect model ocular...
Aim . To identify and analyze changes of arterial stiffness (AS) parameters in breast cancer patients undergoing combination anthracycline-containing chemotherapy (ACCT). Material methods Fifty women with verified aged 46,7±7 years indications for combined ACCT were assessed AS (carotid-femoral pulse wave velocity (cfPWV) (m/s); cardio-ankle vascular index (CAVI); (caPWV) β-stiffness index, novel Russian Stelari haStart indices) at 4 visits as follows: before ACCT, after 8-12, 20-24 48 weeks...
Aim. The assessment of global longitudinal deformation and velocity the left ventricle (LV) in arterial hypertension (AH) patients for diagnostics preclinical systolic function disorders. Material methods. Totally, 105 AH investigated, age 53,3±5,7 y. o., 35 gender matched almost healthy persons. All underwent standard clinical functional investigation with evaluation diastolic additional theLV. Results. In theLVhypertrophy (LVH) more often was associated male higher levels pressure, which...
Modern breast cancer chemotherapy regimens (BC) consider individual patient parameters and ranges of cardiotoxic doses. However, clinicians often record clinical laboratory-instrumental signs cardio- vasculotoxicity in patients, which emphasizes the high importance searching for markers early toxic response. To study characteristics response arterial stiffness on background anthracycline-containing to determine potential BC patients. 20 women with a were included. The patients received 4...
Cardiovascular disease (CVD) remains the leading cause of death in most developed countries. Morphological and functional status large arteries plays an important role pathogenesis CVD. At moment, there are two main methods aortic stiffness assessment: pulse wave velocity (PWV) measurement central PW analysis. In advanced age, increases, which manifests increased PWV, elevated blood pressure, parameters reflected PW. Similar changes can be observed young patients with arterial hypertension....
The presence of metabolic syndrome (MS) in a patient allows him to be assigned group at high risk for atherosclerosis, cardiovascular events, coronary heart disease, and type 2 diabetes mellitus. In addition, MS negatively affects not only the vessels, but also kidney function, which leads chronic disease (CKD). is pathogenetically associated with CKD an independent prognostic factor development latter, namely, involvement frequently determines prognosis quality life these patients. paper...
Aim. To assess the influence of retinol-binding protein synthetized by adipose tissue, on clinical course and prognosis arterial hypertension (AH). Material methods. Totally, 168 patients included, with AH 1-3 grade. Study protocol included general investigation (at inclusion, in 1, 4 9 months) analysis complaints, anamnesis, physical examination, additional laboratory instrumental In 78 among level retinolbinding RBP4 was measured blood serum. Results . Increased correlated significantly...
A plenty of trials confirm the importance aortic wall stiffness evaluation during estimation cardiovascular risk and need for novel drugs influencing this parameter. Most hypotensive medications modify arterial siffness by one or another way. So usage drug combination might be more effective. Insufficient impact betaadrenoblockers on central artrial pressure is linked to peripheral vasoconstriction. The within class having vasodilatory properties significantly reduce pressure.
Recently, chemotherapy is one of the most trustworthy methods for treatment malignant tumors and blood pathology. However clinical effect drugs not always matches with safety. These facts play as a solid evidence necessity studying problems related to side effects drugs, and, particularly, cardiotoxicity, reversible and/or irreversible damage cardiomyocytes. Currently, sensitive ad specific markers myocardium cells are troponins T I. According this, main aims this article analysis literary...
КОРМОВАЯ ЦЕННОСТЬ РАЗНЫХ ПО СПЕЛОСТИ СОРТОВ ЛЯДВЕНЦА РОГАТОГО В ЗАВИСИМОСТИ ОТ ФАЗ СКАШИВАНИЯ
Tumor cell proliferation and angiogenesis are essential factors for tumor growth, progression, metastasis. Objective: to assess the relationship between values of proliferative activity morphometric parameters intratumoral microvessels in metastatic localized carcinomas kidney. Materials methods. Surgical specimens taken from 54 patients (32 men 22 women) aged 26 69 years (mean age 55 ± 1.5 years) with verified diagnosis clear-cell renal carcinoma (RCC) were studied. Conclusion....
In the course of experiment, effect increasing doses nitrogen fertilizers on yield clover meadow variety Nadezhny, entered in State Register Breeding Achievements 2012, was analyzed. A comparison is also made this influence with timothy Leningradskaya 204. It established that pre-sowing introduction mineral for and has influenced productivity these crops, but nature varies depending type grass. The N20 against background P30K90, which provided an increase control 51.2% green mass 33.6%...
Abstract. The purpose of the research is to conduct a comparative assessment variety numbers (height, yield green mass and air-dry matter, percentage leaf content, yield) identify most productive for creating new varieties. object was 2 (A-44 S-434) as productive, in comparison with standard zoned meadow clover Smolenskiy 29 conditions relatively aligned background mineral nutrition, optimal density standing herbage from first stages selection, timing sowing timely care harvesting....
The article presents the results of a test new varietal species baby eagles in breeding nursery 2018 - 2019. options for first and second year use were evaluated. purpose these studies was to identify most valuable economic traits highly productive varieties further work. Weather climatic conditions generally favorable wintering development plants horned calves spring summer. During field trials, it found that terms green mass yields total over two years use, E-25 variant stood out (+ 30.5%...
OBJECTIVE To identify correlations between parameters of vascular stiffness and characteristics the clinical course acute cerebrovascular accident (stroke). MATERIAL AND METHODS Two hundred seven patients with stroke (mean age 64.6±10.9 years; 115 men) treated in a neurological department «Municipal Clinical Hospital Br. Bakhrushins Health Care Department Moscow» were studied. All underwent standard clinical-instrumental examination, including assessment arterial by sphygmography. Analysis...
Aim. In the study we evaluated influence of antihypertension therapy on 24-hour central BP and parameters aorta stiffness in hypertensive patients with obesity. Material methods. Totally, included 80 AH obesity, at age 35-55 y.o. All underwent clinical, laboratory instrumental assessment, including office, home measurement BP. were randomized to 3 groups: 30 received fixed combination trandolapril/ verapamil daily dosage 2/180 mg, 25 — free bisoprolol/indapamid 5-10/1,5 mg per day, taking...