- Genomics and Phylogenetic Studies
- Microbial Natural Products and Biosynthesis
- Parasitic Infections and Diagnostics
- Bacterial Genetics and Biotechnology
- Fermentation and Sensory Analysis
- Viral Infections and Vectors
- Plant Pathogens and Fungal Diseases
- Catalysis and Hydrodesulfurization Studies
- Enzyme Catalysis and Immobilization
- Toxoplasma gondii Research Studies
- Marine Sponges and Natural Products
- Catalysis for Biomass Conversion
Universidad Complutense de Madrid
2017
Consejo Superior de Investigaciones Científicas
2014-2016
Centro de Investigaciones Biológicas Margarita Salas
2014-2016
Universidad de Oviedo
2014
Centro Nacional de Biotecnología
2012
Streptomyces albus J1074 is a streptomycete strain widely used as host for expression of secondary metabolite gene clusters. Bioinformatic analysis the genome this organism predicts presence 27 clusters metabolites. We have three different strategies activation some these silent/cryptic in S. J1074: two hybrid polyketide-non-ribosomal peptides (PK-NRP) (antimycin and 6-epi-alteramides), type I PK (candicidin), non-ribosomal (NRP) (indigoidine) glycosylated compounds (paulomycins). By...
Background Bacterial two-component signal transduction regulatory systems are the major set of signalling proteins frequently mediating responses to changes in environment. They typically consist a sensor, membrane-associated histidine kinase and cytoplasmic response regulator. The sensor detects environmental or stress, whereas protein controls cellular usually by gene transcription modulation. Methodology/PrincipalFindings Streptomyces coelicolor two genes operon SCO5784-SCO5785 encodes...
Pseudomonas azelaica HBP1 (DSM 8897) is one of the few bacteria able to completely mineralize 2-hydroxybiphenyl biocide. Here, we report draft genome sequence this strain (7.4 Mbp; G+C content, 63.5%) and findings obtained from its annotation.