Melioidosis is a tropical infectious disease with diverse clinical presentations. We aimed to investigate the characteristics and mortality risk factors of patients diagnosed melioidosis in past 10 years. This was retrospective cohort study conducted at quaternary care centre South India. Clinical, demographic, biochemical data cultures were collected between January 2011 December 2020 from medical records. Logistic regression analysis performed screen addition descriptive statistics...

Purpose: This study aims to gauge the perception and adoption rates of telemedicine amongst patients with non-communicable diseases (NCD) as opposed in-person consultations in a quaternary care center South India. Patients Methods: A web-hosted 21-item cross-sectional survey was distributed 220 randomly selected routine appointment one seven departments caring for NCDs center. Descriptive analysis inferential analyses were done. Paired samples T -test Pearson's Chi-square test used...

Objective The aim of this study is to develop a machine learning (ML) model accurately predict liver enzyme elevation in rheumatoid arthritis (RA) patients on treatment with methotrexate (MTX) using electronic health record (EHR) data from real-world RA cohort. Methods Demographic, clinical, biochemical, and prescription information 569 initiated MTX were collected retrospectively. primary outcome was the transaminase above upper limit normal (40 IU/mL), following initiation MTX. total...

Background: Rheumatoid arthritis (RA) is the most common form of autoimmune inflammatory with an Indian prevalence around 0.75%. Nearly 55% Indians resort to primary health-care centers as their first point contact. MBBS students must be well equipped diagnose and treat patients RA within community refer relevant cases appropriately higher medical facilities. Materials Methods: A cross-sectional study was conducted assessing basic knowledge in senior undergraduate two domains. The domain...

Background: While many factors are known to play a role in outcomes of sepsis, the micronutrients such as zinc remains gray area. This study assesses correlation plasma levels with mortality and severity sepsis. Objective was association between sepsis.Methods: Comparative prospective observational which included 89 patients proven sepsis according society critical care medicine (SCCM) guidelines. The conducted at tertiary centre South India. A total who were admitted into medical ICU...

Background: Viridans Group Streptococci (VGS) are a group of distinct species that can cause bacteraemia and other invasive infections.They also among the common organisms causing infective endocarditis.Data on epidemiology clinical profile VGS is limited, especially from India.Methods: We conducted an electronic medical recordbased retrospective analysis patients with admitted to our hospital between January 2012 December 2021.Blood cultures were incubated by BacT/ALERT system bacterial...

<h3>Background:</h3> The FIQ (Fibromyalgia Impact Questionnaire) was first published in 1991 and had 19 items which were recalled over a week. scoring system is highly reliable recognised as an outcome measure that covers the multiple domains of Fibromyalgia¹. A prior study by Benett et al² have shown 14% change total score represents Minimum Clinically Important Difference(MCID) Fibromyalgia. revised 2009 to 20 item Fibromyalgia Questionnaire Revised or FIQR. However,...

Sulfasalazine has been widely used in treatment of rheumatoid arthritis and spondyloarthritis. This study aims to assess persistence with sulfasalazine also frequency severity adverse drug reactions (ADRs) encountered this very well-established disease-modifying anti-rheumatoid drug.This retrospective was done 1,114 patients from medicine rheumatology outpatient departments six centers across India. The inclusion criteria taking sulfasalazine. Patients receiving for or spondyloarthritis were...

Abstract Background In autoimmune inflammatory rheumatological diseases, routine cardiovascular risk assessment is becoming more important. As an increased disease (CVD) recognized in patients with fibromyalgia (FM), a combination of traditional CVD tool Machine Learning (ML) predictive model could help to identify non-traditional factors. Methods This study was retrospective case–control conducted at quaternary care center India. Female diagnosed FM as per 2016 modified American College...

Background: Assessment of awareness common rheumatological diseases amongst final year medical undergraduate students – single centre questionnaire-based survey.Methods: A cross-sectional survey was conducted during a national summit. Participants were asked to fill out 10-question (online link/in print). Results summarized using descriptive statistics.Results: total 162 completed the survey. Only 18 respondents able score more than 50% in all domains with only one respondent getting...

Background: Over the decades, studies from various populations have found fibromyalgia and dysautonomia to be linked. However, recent evidence Indian contradicts these findings. Methods: This cross-sectional study, conducted in a quaternary care centre South India, recruited 30 women with (2016 ACR criteria) age sex-matched controls. We assessed all participants using Composite Autonomic Symptom Score (COMPASS-31) questionnaires, Sympathetic Skin Response (SSR) for sympathetic dysfunction...

Introduction. There is a scarcity of information available on clinical and laboratory features adult-onset idiopathic autoimmune uveitis. Therefore, we conducted single centre descriptive cross-sectional study. Patients Methods. A chart review all patients with uveitis onset after 18 years age who were referred to the rheumatology department between January 2017 December 2018 was performed. Their features, demographic HLA-B genotypes documented described. Results. Out 210 rheumatology, 66...

We report a case of 12-year-old male who initially presented with active systemic lupus erythematosus (SLE) nephritis and secondary macrophage activation syndrome (MAS). He went on to develop left-sided upper motor neuron (UMN) facial palsy lupus-related tumefactive demyelination. Tumefactive lesions demyelination are very rare manifestation in neuropsychiatric SLE. This child responded aggressive immunosuppression steroids cyclophosphamide.

The second wave of COVID-19 devastated the medical sector on India and government has implored students to aid frontline workforce. This study aims assess knowledge, attitude practice (KAP) South Indian Medical regarding pandemic their career aspirations.This is an online questionnaire based, cross-sectional featuring a pre-validated with KAP section aspiration survey section, which was distributed schools between November December 2020. Three hundred four responses were included for...

We present a case of hemophagocytic lymphocytosis (HLH) that occurred secondary to combination Epstein Barr virus (EBV) infection and systemic lupus erythematosus (SLE) in early pregnancy. A 29-years-old lady presented with complaints fever, vomiting loose stools. She underwent successful in-vitro fertilization (IVF) embryo transfer 20 days prior the onset these symptoms. Her blood investigations revealed anemia, neutropenia, hyperferritinemia hypertriglyceridemia, eventually resulting...

Fibromyalgia is characterized by chronic widespread pain, which has been linked to neuroinflammation. Hematological indices, i.e., neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), and mean platelet volume (MPV) have shown be effective markers in neurological diseases like depression.To study the association between fibromyalgia severity hematological indices (NLR, PLR, MPV).This was a hospital-based cross-sectional of patients satisfying 2016 modification 2010/11 ACR...

Introduction: Gram Negative Bacilli (GNB) account for about 70% of Hospital Acquired Pneumonia (HAP), Ventilator (VAP) and Healthcare Associated (HCAP). Increasing use carbapenems lead to infections caused by GNBs with therapeutically challenging Extended-Spectrum Beta-Lactamases (ESBLs). Aim: To assess the risk factors clinical outcomes associated HAP, VAP HCAP Carbapenem Resistant (CR) GNB at a Tertiary Care Centre. Materials Methods: The present study was prospective cohort which...

Objective: The objective of this study was to describe clinical and radiological features assess the treatment response in an Indian cohort chronic recurrent multifocal osteomyelitis (CRMO). Methods: Case records children who were diagnosed with CRMO between January 2014 December 2017were reviewed retrospectively. cases based on typical history along magnetic resonance imaging (MRI). Remission defined as resolution symptoms restoration functional status normalization inflammatory markers....

Background: Autoimmune uveitis is frequently referred to a rheumatologist for evaluation &amp; treatment. While clinical characteristics of HLA B27 associated are well documented, scanty information available on non HLA-B27 autoimmune uveitis. We have described the our patients non-B27 and compare same with Asian Indian HLAB27 Objectives: To describe Methods: Retrospective review records from hospital’s electronic medical record database included all cases that were rheumatology January 2017...