A5013774015- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- Antibiotics Pharmacokinetics and Efficacy
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Use and Resistance
- Vitamin C and Antioxidants Research
- Respiratory Support and Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Urinary Tract Infections Management
- Alcoholism and Thiamine Deficiency
- Bacterial Identification and Susceptibility Testing
- Climate Change and Health Impacts
- Nosocomial Infections in ICU
- Thermal Regulation in Medicine
- Atrial Fibrillation Management and Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Infectious Encephalopathies and Encephalitis
- Vitamin K Research Studies
- Machine Learning in Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Neonatal and Maternal Infections
- Global Maternal and Child Health
King Abdullah International Medical Research Center
2018-2025
University of East Anglia
2022-2025
King Saud bin Abdulaziz University for Health Sciences
2018-2025
King Abdulaziz Medical City
2019-2025
European Organisation for Research and Treatment of Cancer
2021-2023
National Guard Health Affairs
2019-2023
Security Forces Hospital
2021
Princess Nourah bint Abdulrahman University
2021
King Abdulaziz Hospital
2020-2021
King Abdulaziz University
2020-2021
Background Caesarean section is considered a relatively preferable and safe method of delivery as compared to normal delivery. Since the last decade, its prevalence has increased in both developed developing countries. In context countries viz., South Asia (the highest populated region) South-East third-highest region), where significant proportion home deliveries were reported,however, preference for, caesarean associated factors are not well understood. Objective To study Asian determine...
The recent outbreak of coronavirus (COVID-19) has infected around 1 560 000 individuals till 10 April 2020, which resulted in 95 deaths globally. While no vaccine or anti-viral drugs for COVID-19 are available, lockdown acts as a protective public health measures to reduce human interaction and lower transmission. study aims explore the impact delayed planning lack inadequate implementation lockdown, on transmission rate COVID-19.Epidemiological data incidence mortality cases reported by...
Ascorbic acid represents an appealing option for clinicians to utilize in the context of global COVID-19 pandemic due its proposed clinical efficacy, relative safety, and low cost. The aim this study was evaluate efficacy safety using ascorbic supplemental doses as adjunctive therapy patients critically ill with COVID-19. This a two-center, non-interventional, retrospective cohort study. All adult admitted ICU confirmed diagnosis between March 1st December 31st, 2020, were included final...
Abstract Background Inhaled nitric oxide (iNO) is used as rescue therapy in patients with refractory hypoxemia due to severe COVID-19 acute respiratory distress syndrome (ARDS) despite the recommendation against use of this treatment. To date, effect iNO on clinical outcomes critically ill moderate-to-severe ARDS remains arguable. Therefore, study aimed evaluate ARDS. Methods This multicenter, retrospective cohort included adult confirmed treated from March 01, 2020, until July 31, 2021....
The outbreak of coronavirus disease, 2019 (COVID-19), which started from Wuhan, China, in late 2019, have spread worldwide. A total 5,91,971 cases and 2,70,90 deaths were registered till 28th March, 2020. We aimed to predict the impact duration exposure COVID-19 on mortality rates increment.
Abstract Background Thiamine is a precursor of the essential coenzyme thiamine pyrophosphate required for glucose metabolism; it improves immune system function and has shown to reduce risk several diseases. The role in critically ill septic patient been addressed multiple studies; however, it’s COVID-19 patients still unclear. aim this study was evaluate use as an adjunctive therapy on mortality patients. Methods This two-center, non-interventional, retrospective cohort admitted intensive...
Zinc is a trace element that plays role in stimulating innate and acquired immunity. The of zinc critically ill patients with COVID-19 remains unclear. This study aims to evaluate the efficacy safety sulfate as adjunctive therapy COVID-19.Patients aged ≥ 18 years who were admitted intensive care unit (ICU) two tertiary hospitals Saudi Arabia retrospectively assessed for use from March 1, 2020 until 31, 2021. After propensity score matching (1:1 ratio) based on selected criteria, we...
Abstract The use of tocilizumab for the management COVID-19 emerged since it modulates inflammatory markers by blocking interleukin 6 receptors. Concerns regarding higher thrombosis risk while using were raised in literature. aim this study is to investigate association between therapy and development thromboembolic events critically ill patients. A propensity score-matched, multicenter cohort adult patients with COVID-19. Eligible admitted ICU March 2020 July 2021 categorized into two...
Background Sepsis remains a major cause of death, with high mortality and morbidity rates in children. The may be associated several factors, including differences cultures the type organism. This study was aimed at evaluating characteristics outcomes negative bacterial blood culture compared to those positive children severe sepsis/septic shock. Methods A retrospective cohort conducted pediatric intensive care unit (PICU) tertiary medical center. All patients, from newborn 14 years age,...
Background The incidence of colorectal cancer (CRC) is increasing nationally, emphasizing the importance early detection. Late-stage diagnosis, particularly with peritoneal metastasis (PM), associated poor outcomes despite advancements in treatment. PM poses a challenge owing to lack standardized treatment, although cytoreductive surgery (CRS) hyperthermic intraperitoneal chemotherapy (HIPEC) shows promise improving survival rates. This study aimed document and risk factors for patients...
Limited evidence is available regarding the safety and effectiveness of early high protein intake in critically ill patients with COVID-19. Therefore, this study aims to assess advancement during nutritional support these patients. A multi-center retrospective cohort included adult COVID-19 admitted Intensive Care Units (ICUs) at three centers Saudi Arabia. Patients were grouped into two groups based on day feeding initiation low (≤0.8 mg/kg/day) versus (>0.8 groups. Acute kidney injury...
The integration of machine learning (ML) in automated post-surgical monitoring represents a pivotal advancement healthcare, aiming to enhance patient outcomes by enabling early detection complications. This research critically examines the efficacy various ML algorithms predicting post-operative complications through real-time analysis preoperative and intraoperative data. Utilizing multimodal approaches, including wearable sensors biometric data, study highlights potential for improving...
Classical Hodgkin Lymphoma (cHL) is a prominent B-cell neoplasm, that impacts global and Saudi populations. Given limited large-scale studies focusing on HL in Arabia, this retrospective multicenter cohort study reviewed the characteristics clinical outcomes of patients with cHL Arabia. All adult aged 18 years older newly diagnosed at three local tertiary care hospitals were included between January 2016 December 2021. The primary outcome was to identify patient's features such as...
Abstract Background Previous studies have shown that non-critically ill COVID-19 patients co-infected with other respiratory viruses poor clinical outcomes. However, limited focused on this co-infections in critically patients. This study aims to evaluate the outcomes of infected and by viruses. Methods A multicenter retrospective cohort was conducted for all adult who were hospitalized ICUs between March, 2020 July, 2021. Eligible sub-categorized into two groups based simultaneous...
The 2019-Coronavirus (COVID-19) pandemic has had a global impact. effect of environmental temperature on transmissibility and fatality rate COVID-19 protective efficacy Bacillus Calmette-Guérin (BCG) vaccination towards remains ambiguous. Therefore, we explored the impact neonatal BCG coverage COVID-19. data for reported cases, deaths were collected from 31st December 2020 to 3rd April 67 countries. Temperature split into quartiles all three categories (minimum temperature, maximum mean...
Atrial fibrillation (Afib) can contribute to a significant increase in mortality and morbidity critically ill patients. Thus, our study aims investigate the incidence clinical outcomes associated with new-onset Afib patients COVID-19. A multicenter, retrospective cohort includes adult COVID-19 admitted intensive care units (ICUs) from March, 2020 July, 2021. Patients were categorized into two groups (new-onset vs control). The primary outcome was in-hospital mortality. Other secondary, such...
Abstract Background Dexamethasone usually recommended for patients with severe coronavirus disease 2019 (COVID-19) to reduce short-term mortality. However, it is uncertain if another corticosteroid, such as methylprednisolone, may be utilized obtain better clinical outcome. This study assessed dexamethasone’s and safety outcomes compared methylprednisolone. Methods A multicenter, retrospective cohort was conducted between March 01, 2020, July 31, 2021. It included adult COVID-19 who were...
There is increasing evidence suggesting that ABO blood type may play a role in the immunopathogenesis of COVID-19 infection. In addition to type, Rhesus (Rh) factor has also been implicated various disease processes. Therefore, our study aimed assess association between both and Rh types critically ill patients with their clinical outcomes.
Purpose Coagulation abnormalities are one of the most important complications severe COVID-19, which might lead to venous thromboembolism (VTE). Hypercoagulability with hyperfibrinogenemia causes large vessel thrombosis and major thromboembolic sequelae. Statins potentially a potent adjuvant therapy in COVID-19 infection due their pleiotropic effect. This study aims evaluate effectiveness statins reducing risk among hospitalized critically ill patients COVID-19. Methods A multicenter,...
Abstract Background Caesarean section is considered a preferable and safe method of delivery. In the last decade, its prevalence has increased in both developed developing countries. context countries viz., South Asia (the highest populated region) South-east third region), preference for, variation in, caesarean delivery associated maternal socioeconomic characteristics are still to be determined. Objective To study magnitude Asian countries, by correlating with for sections. Methodology...
Patients with underlying heart failure (HF) in the setting of COVID-19 who require admission to intensive care unit (ICU) might present a unique set challenges. This study aims extensively describe characteristics and outcomes patients HF were admitted ICU COVID-19. We conducted multicenter retrospective analysis for all adult an objectively confirmed diagnosis ICUs between March 1 August 31, 2020, Saudi Arabia. A total 723 critically ill into during period: 59 664 no before ICU. had...