A5088537643- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- Antibiotic Use and Resistance
- Pharmaceutical Practices and Patient Outcomes
- Venous Thromboembolism Diagnosis and Management
- SARS-CoV-2 and COVID-19 Research
- Antibiotics Pharmacokinetics and Efficacy
- Cardiac, Anesthesia and Surgical Outcomes
- Vitamin C and Antioxidants Research
- Atrial Fibrillation Management and Outcomes
- Urinary Tract Infections Management
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Family and Patient Care in Intensive Care Units
- COVID-19 and healthcare impacts
- Renal function and acid-base balance
- Nosocomial Infections in ICU
- Patient Safety and Medication Errors
- Lipoproteins and Cardiovascular Health
- Electrolyte and hormonal disorders
- Cardiac Arrest and Resuscitation
- Infectious Encephalopathies and Encephalitis
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
King Abdulaziz University
2014-2025
Saudi Heart Association
2023-2025
King Abdulaziz Hospital
2021-2023
King Saud bin Abdulaziz University for Health Sciences
2021
King Abdulaziz Medical City
2021
Security Forces Hospital
2021
Princess Nourah bint Abdulrahman University
2021
Saudi Commission for Health Specialties
2021
University of Arizona
2014-2019
Banner - University Medical Center Tucson
2014-2015
Ascorbic acid represents an appealing option for clinicians to utilize in the context of global COVID-19 pandemic due its proposed clinical efficacy, relative safety, and low cost. The aim this study was evaluate efficacy safety using ascorbic supplemental doses as adjunctive therapy patients critically ill with COVID-19. This a two-center, non-interventional, retrospective cohort study. All adult admitted ICU confirmed diagnosis between March 1st December 31st, 2020, were included final...
Abstract Background Inhaled nitric oxide (iNO) is used as rescue therapy in patients with refractory hypoxemia due to severe COVID-19 acute respiratory distress syndrome (ARDS) despite the recommendation against use of this treatment. To date, effect iNO on clinical outcomes critically ill moderate-to-severe ARDS remains arguable. Therefore, study aimed evaluate ARDS. Methods This multicenter, retrospective cohort included adult confirmed treated from March 01, 2020, until July 31, 2021....
Abstract Background Thiamine is a precursor of the essential coenzyme thiamine pyrophosphate required for glucose metabolism; it improves immune system function and has shown to reduce risk several diseases. The role in critically ill septic patient been addressed multiple studies; however, it’s COVID-19 patients still unclear. aim this study was evaluate use as an adjunctive therapy on mortality patients. Methods This two-center, non-interventional, retrospective cohort admitted intensive...
Zinc is a trace element that plays role in stimulating innate and acquired immunity. The of zinc critically ill patients with COVID-19 remains unclear. This study aims to evaluate the efficacy safety sulfate as adjunctive therapy COVID-19.Patients aged ≥ 18 years who were admitted intensive care unit (ICU) two tertiary hospitals Saudi Arabia retrospectively assessed for use from March 1, 2020 until 31, 2021. After propensity score matching (1:1 ratio) based on selected criteria, we...
The Saudi Society of Clinical Pharmacy (SSCP) is a scientific and professional society in the field clinical pharmacy that operates under Commission for Health Specialties governance. SSCP believes there need to define describe many aspects related profession Arabia. Moreover, an increasing demand promoting concept developing consensus regarding scope practice pharmacist's required postgraduate education training This paper intended present several position statements by pharmacy, training,...
The primary objective was to determine the proportion of hospitals that administered norepinephrine peripheral vasopressor infusions (PVIs) in critically ill adult patients. Secondary objectives were describe how is used such as maximum duration, infusion rate and concentration, most common first-line PVI by country. An international multi-centre cross-sectional survey study conducted intensive care units Australia, US, UK, Canada, Saudi Arabia. Critical pharmacists from 132 institutions...
Abstract The use of tocilizumab for the management COVID-19 emerged since it modulates inflammatory markers by blocking interleukin 6 receptors. Concerns regarding higher thrombosis risk while using were raised in literature. aim this study is to investigate association between therapy and development thromboembolic events critically ill patients. A propensity score-matched, multicenter cohort adult patients with COVID-19. Eligible admitted ICU March 2020 July 2021 categorized into two...
Glycemic variability (GV) has been associated with an increased mortality rate among critically ill patients. The clinical outcomes of having less GV even slight hyperglycemia are better than those tight glycemic control but higher GV. Insulin infusion remains the preferred method to stress in However, its impacts on and patients still need further investigation. This study intended evaluate impact insulin therapy (IIT) compared sliding scale (ISS) extent explore for A prospective,...
Evidence is limited on the optimal utilization of Medication Regimen Complexity - Intensive Care Unit (MRC-ICU) scores for predicting clinical outcomes in critically ill patients. Therefore, this study aims to examine how a high score MRC-ICU within 24 hours ICU admission predicts patients ICUs. A single-center retrospective cohort included adult admitted >72 between January 2021 and December 2021. Patients were categorized into two groups based (≥9 vs. <9) assessed admission. The primary...
Limited evidence is available regarding the safety and effectiveness of early high protein intake in critically ill patients with COVID-19. Therefore, this study aims to assess advancement during nutritional support these patients. A multi-center retrospective cohort included adult COVID-19 admitted Intensive Care Units (ICUs) at three centers Saudi Arabia. Patients were grouped into two groups based on day feeding initiation low (≤0.8 mg/kg/day) versus (>0.8 groups. Acute kidney injury...
Background: The increasing prevalence of extended-spectrum β-lactamase (ESBL)–producing bacteria has limited treatment options for cystitis. recommendation nitrofurantoin is based solely on in vitro studies. Objective: We aimed to evaluate the effectiveness versus comparators treating cystitis due ESBL-producing Enterobacterales clinical setting. Methods: This was a multicenter retrospective cohort study afebrile adults with symptomatic and urine culture ≥10 5 CFU/mL organism susceptible...
Abstract Background Previous studies have shown that non-critically ill COVID-19 patients co-infected with other respiratory viruses poor clinical outcomes. However, limited focused on this co-infections in critically patients. This study aims to evaluate the outcomes of infected and by viruses. Methods A multicenter retrospective cohort was conducted for all adult who were hospitalized ICUs between March, 2020 July, 2021. Eligible sub-categorized into two groups based simultaneous...
There is interest in the use of methocarbamol as an adjunctive agent for pain control after traumatic injury. The primary objective this study was to determine effect on measurements acute This a retrospective, matched cohort conducted at academic medical center United States. Consecutive adult (age ≥18 years) patients who were admitted hospital between June 1, 2012 and 30, 2013 because injury evaluated. Patient cases receiving least 3 days controls that did not receive based age, sex,...
Background Stroke is a leading cause of mortality and disability one the most common neurological conditions globally. Many studies focused on vitamin D as stroke risk factor, but only few its serum level predictor initial clinical severity recovery with inconsistent results. The purpose this study was to assess relationship between levels at admission functional independence discharge in Saudi Arabia. Methodology A retrospective cohort adult ischemic patients who had their tested admitted...
Atrial fibrillation (Afib) can contribute to a significant increase in mortality and morbidity critically ill patients. Thus, our study aims investigate the incidence clinical outcomes associated with new-onset Afib patients COVID-19. A multicenter, retrospective cohort includes adult COVID-19 admitted intensive care units (ICUs) from March, 2020 July, 2021. Patients were categorized into two groups (new-onset vs control). The primary outcome was in-hospital mortality. Other secondary, such...
Abstract Background Dexamethasone usually recommended for patients with severe coronavirus disease 2019 (COVID-19) to reduce short-term mortality. However, it is uncertain if another corticosteroid, such as methylprednisolone, may be utilized obtain better clinical outcome. This study assessed dexamethasone’s and safety outcomes compared methylprednisolone. Methods A multicenter, retrospective cohort was conducted between March 01, 2020, July 31, 2021. It included adult COVID-19 who were...
Abstract Background Recent guidelines recommend using direct oral anticoagulants (DOACs) as first-line agents in patients with non-valvular atrial fibrillation (NVAF). Research is currently investigating the use of Apixaban underweight patients, some results suggesting altered pharmacokinetics, decreased drug absorption, and potential overdosing this population. This study examined effectiveness safety standard dosing adult NVAF weighing less than 50 kg. Methods a retrospective cohort...
There is increasing evidence suggesting that ABO blood type may play a role in the immunopathogenesis of COVID-19 infection. In addition to type, Rhesus (Rh) factor has also been implicated various disease processes. Therefore, our study aimed assess association between both and Rh types critically ill patients with their clinical outcomes.
Purpose Coagulation abnormalities are one of the most important complications severe COVID-19, which might lead to venous thromboembolism (VTE). Hypercoagulability with hyperfibrinogenemia causes large vessel thrombosis and major thromboembolic sequelae. Statins potentially a potent adjuvant therapy in COVID-19 infection due their pleiotropic effect. This study aims evaluate effectiveness statins reducing risk among hospitalized critically ill patients COVID-19. Methods A multicenter,...
Patients with underlying heart failure (HF) in the setting of COVID-19 who require admission to intensive care unit (ICU) might present a unique set challenges. This study aims extensively describe characteristics and outcomes patients HF were admitted ICU COVID-19. We conducted multicenter retrospective analysis for all adult an objectively confirmed diagnosis ICUs between March 1 August 31, 2020, Saudi Arabia. A total 723 critically ill into during period: 59 664 no before ICU. had...