A5101667706- Liver Disease Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- Cancer Immunotherapy and Biomarkers
- Cardiovascular and exercise physiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Head and Neck Cancer Studies
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Sarcoma Diagnosis and Treatment
- Obesity, Physical Activity, Diet
- Pharmacological Effects of Natural Compounds
- Lung Cancer Treatments and Mutations
- Cancer Genomics and Diagnostics
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Pancreatic and Hepatic Oncology Research
- Ferroptosis and cancer prognosis
- Oral health in cancer treatment
- Medical Research and Treatments
- RNA modifications and cancer
- Ultrasound in Clinical Applications
- Adipose Tissue and Metabolism
- Sex work and related issues
- Viral-associated cancers and disorders
- Diverse Approaches in Healthcare and Education Studies
Nanjing Medical University
2025
Sun Yat-sen University Cancer Center
2019-2024
Second Affiliated Hospital of Jilin University
2024
Guangzhou Sport University
2019-2024
Fudan University Shanghai Cancer Center
2024
Sun Yat-sen University
2019-2024
Bristol-Myers Squibb (Germany)
2024
Shanghai Medical College of Fudan University
2024
Shanghai Clinical Research Center
2024
Diabetes Australia
2024
This study aimed to explore the effects of endometriosis (EMS)-derived exosomes and miR-301a-3p on polarization macrophages investigate involved molecular mechanism. The were isolated from ectopic endometrial tissues EMS patients normal human serum (NHS). Results transmission electron microscope Nanoparticle Tracking Analysis showed that both EMS-exosomes NHS-exosomes are about 80 nm microvesicles. Exosomal markers CD63 TSG101 abundantly expressed in NHS-exosomes. No negative marker Calnexin...
Background: The optimal subsequent management for patients with initially unresectable hepatocellular carcinoma (uHCC) who have achieved complete response (CR) following conversion therapy remains unclear. This study aims to evaluate the feasibility and outcomes of watch-and-wait (W-W) strategy versus surgical resection (SR) these patients. Materials Methods: retrospective reviewed uHCC underwent employing transarterial therapies combined or without systemic therapies. Radiologic CR (rCR),...
Hepatocyte deletion of estrogen receptor alpha (LKO-ERα) worsens fatty liver, dyslipidemia, and insulin resistance in high-fat diet fed female mice. However, whether or not hepatocyte ERα regulates reverse cholesterol transport (RCT) mice has yet been reported.Using LKO-ERα wild-type (WT) littermates a Western-type diet, we found that impaired vivo RCT measured by the removal 3H-cholesterol from macrophages to subsequently feces, but male Deletion decreased capacity isolated HDL efflux...
Abstract As the most promising “liquid biopsy”, analysis of circulating tumor cells (CTCs) provides noninvasive access to obtain biological information solid tumors. It not only advances understanding mechanisms underlying metastasis, relapse, and chemoresistance, but also promotes development precision medicine. Over past decade, rapid in micro/nanomaterials microfluidics have overcome technical challenges capturing CTCs, allowing efficient enrichment sensitive detection. Beyond capture...
Obesity is a systemic and chronic inflammation, which seriously endangers people’s health. People tend to diet control weight, the short-term effect of dieting in losing weight significant, but prognosis limited. With loss recovery occurring frequently, people focus on cycling. The cycling certain tissue body also has different conclusions. Therefore, this article systematically reviews effects finds that multiple (1) increased fat deposition central areas, lean mass decreased period, harms...
As a malignant disease that seriously threatens human health, hepatocellular carcinoma (HCC) lacks effective early screening and prognostic assessment methods. Herein, we developed method for efficient capture multiphenotype analysis of circulating tumor cells (CTCs) carcinoma. The anti-ASGPR antibody the anti-EpCAM were modified in parallel on deterministic lateral displacement (DLD)-patterned microfluidic Synergetic-Chip to enhance efficiency by complementary effect. CTCs detected 45 out...
ABSTRACT Using machine learning approaches, we developed and validated a novel prognostic model for oesophageal squamous cell carcinoma (ESCC) based on glycolipid metabolism‐related genes. Through integrated analysis of TCGA GEO datasets, established robust 15‐gene signature that effectively stratified patients into distinct risk groups. This demonstrated superior value revealed significant associations with immune infiltration patterns. High‐risk exhibited reduced infiltration, particularly...
Background: Stem cell transplantation is emerging as a potential therapeutic strategy in several autoimmune diseases. However, the safety and feasibility of long-term combined intravenous (IV) intrathecal (IT) administration hUC-MSCs relapse remitting multiple sclerosis (RRMS) neuromyelitis optica (NMO) largely unknown. Objectives: In this study, we followed up IV IT human umbilical cord mesenchymal stem cells (hUC-MSCs) patients with RRMS NMO. Methods: Five NMO 5 were treated intravenously...
Fatty liver is one of the most pervasive diseases worldwide. Probiotics play an important role in progression disease, but their effects on host regulation are poorly understood. This study investigated protective lactobacillus gasseri (L. gasseri) against high-cholesterol diet (HCD)-induced fatty injury using a zebrafish larvae model. Liver pathology, lipid accumulation, oxidative stress and hepatic inflammation were evaluated to demonstrate changes spectrum injury. Moreover, multiple...
Antiretroviral therapy (ART) administered in clinical trial settings virtually eliminates the sexual transmission of human immunodeficiency virus (HIV) serodiscordant couples, but effectiveness treatment as prevention community is debated. Conflicting results from previous analyses a Chinese cohort underscore importance determining ART delivered resource limited settings.All available years data (2006-2012) local disease control records HIV patients and their seronegative spouses Henan...
Mounting evidence has shown that CETP important physiological roles in adapting to chronic nutrient excess, specifically, protect against diet-induced insulin resistance. However, the underlying mechanisms for protective of metabolism are not yet clear. Mice naturally lack expression. We used transgenic mice with a human minigene (huCETP) controlled by its natural flanking region further understand CETP-related physiology response obesity. Female huCETP and their wild-type littermates were...