Sucheta Singh

ORCID: 0000-0003-2470-2114
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Research Areas
  • Plant-Microbe Interactions and Immunity
  • Plant tissue culture and regeneration
  • Phytochemicals and Medicinal Plants
  • Berberine and alkaloids research
  • Alkaloids: synthesis and pharmacology
  • Phytochemistry and Biological Activities
  • Heavy metals in environment
  • Trace Elements in Health
  • Medicinal Plants and Neuroprotection
  • Essential Oils and Antimicrobial Activity
  • Plant biochemistry and biosynthesis
  • Chromium effects and bioremediation
  • Botanical Research and Chemistry
  • Ethnobotanical and Medicinal Plants Studies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Agricultural pest management studies
  • Microbial Natural Products and Biosynthesis
  • Mycorrhizal Fungi and Plant Interactions
  • Agriculture, Plant Science, Crop Management
  • Chemical synthesis and alkaloids
  • Plant Pathogenic Bacteria Studies
  • Phytochemistry and biological activity of medicinal plants
  • Composting and Vermicomposting Techniques
  • Plant Pathogens and Fungal Diseases
  • Legume Nitrogen Fixing Symbiosis

Central Institute of Medicinal and Aromatic Plants
2005-2024

Indian Council of Medical Research
2023

National Botanical Research Institute
2022

Maharshi Dayanand University
2022

Academy of Scientific and Innovative Research
2019-2021

University of Missouri–Kansas City
2021

Nirma University
2020

Banaras Hindu University
1979-2013

Command Hospital
2011

Institute of Medical Sciences
1998-2004

Abstract Not much is known about the mechanism of endophyte-mediated induction secondary metabolite production in Catharanthus roseus . In present study two fungal endophytes, Curvularia sp. CATDLF5 and Choanephora infundibulifera CATDLF6 were isolated from leaves plant that found to enhance vindoline content by 229–403%. The endophytes did not affect primary metabolism as maximum quantum efficiency PSII, net CO 2 assimilation, biomass starch endophyte-inoculated plants was similar...

10.1038/srep26583 article EN cc-by Scientific Reports 2016-05-25

10.1023/a:1016354713289 article EN World Journal of Microbiology and Biotechnology 2002-01-01

Abstract Tissue specific biosynthesis of secondary metabolites is a distinguished feature medicinal plants. Withania somnifera , source pharmaceutically important withanolides biosynthesizes withaferin-A in leaves and withanolide-A roots. To increase the planta production, sustainable approach needs to be explored. Here, we isolated endophytes from different parts W. plants their promising role withanolide was established both in-vivo grown as well in-vitro raised composite Overall, fungal...

10.1038/s41598-018-23716-5 article EN cc-by Scientific Reports 2018-03-29

The aim of this study was to determine whether ACC (1-aminocyclopropane-1-carboxylic acid) deaminase-containing bacterial treatments could enhance the tolerance poppy (Papaver somniferum L.) plants against biotic stress downy mildew caused by Peronospora sp.Three different genotypes P. somniferum, that is, Sampada, J-16 and I-14 were included in experiment. bacteria Pseudomonas putida (WPTe) reduced disease severity significantly improved growth yield plants. chlorophyll content,...

10.1111/jam.13417 article EN Journal of Applied Microbiology 2017-02-10

Introduction The exact role of copper and zinc in the etiology carcinoma gallbladder is unclear. Some studies suggest Cu/Zn ratio a good indicator extent prognosis gastrointestinal tract. aim present study to estimate micronutrient profile serum, tissues, bile patients with benign malignant diseases. Methods was carried out 60 comprising 30 each cholelithiasis, age sex matched controls. Copper levels were estimated blood, bile, tissue using Perkin Elmer Model 2380 Atomic absorption...

10.1002/jso.20306 article EN Journal of Surgical Oncology 2005-01-01

The aim of this study was to identify and characterize promising endophytes capable enhancing the content root alkaloids ajmalicine serpentine in low alkaloid yielding genotype Catharanthus roseus cultivar Prabal possible mechanisms involved.Of four strains isolated from alkaloid-rich C. Dhawal, endophytic CATDLF5 (Curvularia sp.) CATDLF6 (Choanephora infundibulifera) enhanced by 211·7-337·6%, while CATDRF2 (Aspergillus japonicus) CATDS5 (Pseudomonas increased 123·4-203·8% Prabal....

10.1111/jam.14546 article EN Journal of Applied Microbiology 2019-12-10

Aims: To investigate intracellular localization of nickel and its chemical nature in Pseudomonas aeruginosa. Methods Results: Transmission electron micrographs Ni‐loaded bacteria exhibited a darkened opaque zone throughout the cell periphery. Energy dispersive X‐ray analysis confirmed deposition metallic nickel. Cell fractionation revealed that 88% accumulated was restricted to periplasm membrane. diffraction patterns ascertained cellular Ni as phosphide (Ni5P4, NiP2 Ni12P5) carbide (Ni3C)...

10.1046/j.1472-765x.2001.00878.x article EN Letters in Applied Microbiology 2001-04-11

Carcinoma of the gall bladder is third most common malignancy gastrointestinal tract in eastern Uttar Pradesh and western Bihar regions India.1 The two lie down stream river Ganges, which main source drinking, bathing, irrigation water this part India receives untreated domestic sewage industrial agricultural effluent. High concentrations cadmium have been reported sewage, water, vegetables grown area, higher heavy metals than recommended by World Health Organisation from region. Heavy as...

10.1136/bmj.317.7168.1288 article EN BMJ 1998-11-07

A simple reversed-phase liquid chromatographic method is developed for the simultaneous quantitation of anticancerous drugs vincristine, vinblastine, and their precursors catharanthine vindoline using a Merck Chromolith Performance high-performance chromatography column. better resolution obtained in comparison with available particulate-type C18 columns. The column provides good reproducibility peak symmetry. Chromatography carried isocratically mobile phase acetonitrile-0.1M phosphate...

10.1093/chromsci/43.9.450 article EN Journal of Chromatographic Science 2005-10-01

Carcinoma of the gallbladder is third most common malignancy gastrointestinal tract in Eastern Uttar Pradesh and Western Bihar regions India. The main source drinking water this region river Ganges, which heavily polluted with agricultural pesticides. Organochlorine pesticides were estimated bile by gas liquid chromatography 60 patients (30 carcinoma 30 cholelithiasis) to observe its association aetiopathogenesis gallbladder. mean biliary concentration benzene hexachloride (BHC) was found be...

10.1097/00008469-200104000-00006 article EN European Journal of Cancer Prevention 2001-04-01

10.1023/a:1008997718811 article EN World Journal of Microbiology and Biotechnology 1999-01-01

Abstract Comparative study on the essential oil constituents of Pogostemon cablin (Blanco) Benth. (Patchouli) and P. travancoricus Bedd. var. were investigated using GC GC/MS analysis. Eleven compounds from 13 identified. Both species shared like α- β-patchoulene, patchouli alcohol (patchoulol), β-caryophyllene, α-guaiene, seychellene selinene, although quantitatively less in travancoricus.

10.1080/10412905.2009.9700152 article EN Journal of Essential Oil Research 2009-05-01

Papaver somniferum L. produces therapeutically-useful alkaloids like morphine, codeine, papaverine, and thebaine that accumulate in the latex of its capsule. Apart from alkaloids, edible seeds plant have high nutritional value culinary use, with seed oil being rich health-promoting unsaturated fatty acids. Sujata is low alkaloid-producing latex-less variety P. developed an alkaloid-rich gum harvest parent (Sampada) for curtailing narcotic menace morphine opium (dried latex). Earlier, it has...

10.1016/j.cpb.2024.100366 article EN cc-by-nc-nd Current Plant Biology 2024-06-30

Abstract A reversed‐phase column liquid chromatographic method for the analysis of sennosides and B present in leaf pod extracts Cassia angustifolia has been developed using a Symmetry C 18 linear binary gradient profile. The can be utilised quantitative determination other as baseline resolution most constituents was achieved. is economical terms time taken amount solvent used (25 mL) each analysis. validity with respect to confirmed by comparing UV spectra peak those reference compounds...

10.1002/pca.586 article EN Phytochemical Analysis 2001-07-01

A rapid and simple reverse-phase high performance liquid chromatographic method has been developed for the quantitative estimation of medicinally useful laxative principles sennoside B in senna. Using a Bondapak C,, column eluted with methano1:water:acetic acid:tetrahydrofuran (60:38:2:2) both compounds were well resolved recoveries 97 96% respectively.

10.1002/(sici)1099-1565(199603)7:2<73::aid-pca289>3.0.co;2-r article EN Phytochemical Analysis 1996-03-01
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