- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders
- Cultural Heritage Materials Analysis
- Growth Hormone and Insulin-like Growth Factors
- Cancer, Hypoxia, and Metabolism
- Building materials and conservation
- Ancient Mediterranean Archaeology and History
- Heart Rate Variability and Autonomic Control
- Bladed Disk Vibration Dynamics
- Archaeological and Geological Studies
- Diet and metabolism studies
- Classical Antiquity Studies
- Neuroendocrine Tumor Research Advances
- Cardiac Imaging and Diagnostics
- Pain Mechanisms and Treatments
- Gastrointestinal Tumor Research and Treatment
- Coronary Interventions and Diagnostics
- Advanced Measurement and Detection Methods
- Archaeology and Historical Studies
- Mineralogy and Gemology Studies
- Biochemical Acid Research Studies
- Colorectal and Anal Carcinomas
- Turbomachinery Performance and Optimization
Sapienza University of Rome
2020-2024
Heidelberg University
2020-2021
Ansaldo (Italy)
2020
Agostino Gemelli University Polyclinic
2019
Istituti di Ricovero e Cura a Carattere Scientifico
2019
Centro Científico Tecnológico - Tucumán
2013
Ospedale San Giuseppe
2009-2012
University of Milan
2009-2011
Fatebenefratelli Hospital
2006-2009
The presence of an enhanced cortisol secretion in patients with type 2 diabetes is debated. In diabetic subjects, was found to be associated the complications and metabolic control diabetes. We evaluated 170 subjects 71 sex-, age-, BMI-matched nondiabetic subjects.In all we ACTH at 8:00 a.m. basal conditions serum levels 12:00 p.m. (F24) 9:00 after a 1-mg overnight dexamethasone suppression test 24-h urinary free (UFC). patients, chronic (incipient nephropathy, asymptomatic neuropathy,...
Context: In patients with adrenal incidentalomas, subclinical hypercortisolism (SH) is associated an increased prevalence of the metabolic syndrome. The effect surgical/conservative approach debated. Objective: objective study was to determine surgical and conservative approaches on syndrome in incidentalomas. Design: This a retrospective longitudinal (18–48 months follow-up). Setting: conducted in- outpatient basis. Patients: One hundred eight incidentalomas were studied for presence SH,...
In patients with adrenal incidentalomas and subclinical hypercortisolism (SH), the factors influencing bone prevalence of vertebral fractures are debated. Spinal deformity index (SDI), which reflects quality, has never been evaluated.The objective study was to investigate in these SDI fractures.This a retrospective, multicenter study.The conducted on an in- outpatient basis.Patients included 287 incidentaloma (111 eugonadal males, 31 premenopausal, 145 postmenopausal females) 194 controls...
Abstract In patients with adrenal incidentalomas (AIs), cross-sectional studies suggested the presence of an association between subclinical hypercortisolism (SH) and increased prevalence vertebral fractures (VFx) spinal deformity index (SDI), which is a clinical bone quality. No longitudinal investigated incidence VFx SDI changes over time in SH. The aim this study was to evaluate risk SH time. One-hundred-three consecutive AI were studied at baseline after 12 24 months. Patients divided...
Subclinical hypercortisolism (SH) has been associated with increased prevalence of hypertension, type 2 diabetes mellitus, dyslipidaemia, central obesity, osteoporosis and vertebral fractures. We aimed to investigate the accuracy different SH diagnostic criteria in predicting presence complications.This was a retrospective study.We evaluated data from 231 patients (120 women 111 men) affected adrenal incidentalomas (AI).We studied (cortisol after 1 mg overnight dexamethasone suppression test...
Few data are available regarding the need of steroid substitutive therapy after unilateral adrenalectomy for adrenal incidentaloma (AI). It is unknown whether, before surgery, hypothalamic-pituitary-adrenal (HPA) axis secretion parameters can predict post-surgical hypocortisolism.This study aimed to evaluate in AI patients undergoing adrenalectomy, hypocortisolism could be predicted by HPA function.Prospective, multicenter.A total 60 underwent surgical removal (surgical indication: 29...
It is unknown whether the metabolic effects of removal an adrenal incidentaloma (AI) can be predicted by assessment cortisol hypersecretion before surgery.To evaluate accuracy several criteria hypothalamic-pituitary-adrenal axis activity in predicting outcome after adrenalectomy.Retrospective longitudinal study.In 55 surgically treated AI patients (Group 1) surgery and 53 nontreated 2) at baseline, urinary free (UFC), 1 mg overnight dexamethasone-suppression test (1 mg-DST), ACTH, midnight...
Summary Objective Subclinical hypercortisolism (SH) is suggested to exert a deleterious effect on bone. This and the role of gonadal status in male subjects are not fully elucidated. We evaluated bone mineral density (BMD) prevalence vertebral fractures eugonadal with adrenal incidentalomas (AI) without SH. Design 12‐month observational multicentre study was performed between January December 2006 inpatient basis three referral Italian centres. Patients Eighty‐eight consecutive patients AI...
Summary Objective A common polymorphic variant of the growth hormone receptor (GHR) is because genomic deletion exon 3 and has been linked with increased responsiveness to exogenous GH. The impact this polymorphism in acromegaly, a disease characterized by endogenous excess GH partial loss IGF‐I feedback on tumoural secretion, not clear. aim study was investigate possible influences d3GHR GH/IGF‐I relationship metabolic parameters acromegaly. Design methods Retrospective 76 acromegalic...
Vesuvius eruption that destroyed Pompeii in AD 79 represents one of the most important events history. The cataclysm left behind an abundance archeological evidence representing a fundamental source knowledge we have about ancient Roman material culture and technology. A great number textiles been preserved, rarely maintaining traces their original color, since they are mainly mineralized carbonized state. However, outstanding textile sample displays brilliant purple color gold strips. Since...
The production of textiles, in terms weaving techniques, has a long history Europe, and dates back to the Stone Age, time during which first farming communities arrived Mediterranean Central 7th/6th millennium BC. evidence textile tools, like spindle whorls loom weights, demonstrate that people made an important step forward mechanizing this craft, not only twisting fibers interlacing strands purely by hand, but also inventing tools increase efficiency. Through development we see unleashing...