A5073127574- Scheduling and Optimization Algorithms
- Advanced Manufacturing and Logistics Optimization
- Assembly Line Balancing Optimization
- Optimization and Packing Problems
- Neurobiology and Insect Physiology Research
- Supply Chain and Inventory Management
- Ion Channels and Receptors
- Optimization and Search Problems
- Economic and Environmental Valuation
- Operations Management Techniques
- Forecasting Techniques and Applications
- Product Development and Customization
- Olfactory and Sensory Function Studies
- Herbal Medicine Research Studies
- Vehicle Routing Optimization Methods
- Advanced Combustion Engine Technologies
- Neuroscience and Neuropharmacology Research
- Decision-Making and Behavioral Economics
- Hydraulic and Pneumatic Systems
- Adenosine and Purinergic Signaling
- Constraint Satisfaction and Optimization
- Optimization and Mathematical Programming
- Service and Product Innovation
- Electromagnetic Launch and Propulsion Technology
- Cavitation Phenomena in Pumps
College of Idaho
2010-2021
University of Southern California
2007-2011
University of Georgia
2001-2005
IBM Research - Thomas J. Watson Research Center
2003
Georgia Institute of Technology
1994-2000
Duke University
1989-1994
University of California, Los Angeles
1986
Edison International (United States)
1977
Schedulers confronted with significant processing time uncertainty often discover that a schedule which is optimal respect to deterministic or stochastic scheduling model yields quite poor performance when evaluated relative the actual times. In these environments, notion of robustness, i.e., determining best worst-case compared corresponding solution over all potential realizations job times, more appropriate guide selection. this paper, we formalize robust concept for situations uncertain...
Sensory nerves detect an extensive array of somatosensory stimuli, including environmental temperatures. Despite activating only a small cohort sensory neurons, cold temperatures generate variety distinct sensations that range from pleasantly cool to painfully aching, prickling, and burning. Psychophysical functional data show responses are mediated by both C- Aδ-fibers with separate peripheral receptive zones, each which likely provides one or more these sensations. With this diversity in...
This paper focuses on manufacturing environments where job processing times are uncertain. In these settings, scheduling decision makers exposed to the risk that an optimal schedule with respect a deterministic or stochastic model will perform poorly when evaluated relative actual times. Since quality of decisions is frequently judged as if were known priori, robust scheduling, i.e., determining whose performance (compared associated schedule) relatively insensitive potential realizations...
TRPM8 (Transient Receptor Potential Melastatin-8) is a cold- and menthol-gated ion channel necessary for the detection of cold temperatures in mammalian peripheral nervous system. Functioning channels are required behavioral responses to innocuous cool, noxious cold, injury-evoked hypersensitivity, cooling-mediated analgesia, thermoregulation. Because these various roles, ability pharmacologically manipulate function alter excitability cold-sensing neurons may have broad impact clinically....
Most scheduling research has considered optimizing a single performance measure (criterion). In this paper we consider the problem of jobs on machine when desirability schedule is evaluated using more than one measure. The procedures developed here can be used to construct trade-off curves among selected measures. importance curve that it provides complete set possibly optimal solutions for any objective function (cost function) involving only With information, manager concentrate selecting...
Cold temperatures robustly activate a small cohort of somatosensory nerves, yet during prolonged cold stimulus their activity will decrease, or adapt, over time. This process allows for the discrimination subtle changes in temperature. At molecular level, is detected by transient receptor potential melastatin 8 (TRPM8), nonselective cation channel expressed on subset peripheral afferent fibers. We and others have reported that TRPM8 channels also adapt calcium-dependent manner when activated...
In scheduling environments with processing time uncertainty, system performance is determined by both the sequence in which jobs are ordered and actual times of jobs. For these situations, risk achieving substandard can be an important measure effectiveness. To hedge this requires explicit consideration mean variance associated alternative schedules, motivates a β-robustness objective to capture likelihood that schedule yields no worse than given target level. paper we focus on β-robust...
Previous research on the scheduling of multimachine systems has generally focused optimization individual performance measures. This article considers sequencing jobs through a flow shop, where quality resulting schedule is evaluated according to associated levels two criteria, makespan (Cmax) and maximum job tardiness (Tmax). We present constructive procedures that quantify trade-off between Cmax Tmax. The significance this optimal solution for any preference function involving only Tmax...
Flexibility is an effective means by which e-business can hedge against uncertainty in a swiftly changing environment. Systems, applications, and business processes—in short, the entire environment supporting e-business—must seamlessly adapt to changes without costly time-consuming infrastructure overhauls. Decision makers therefore have growing need for knowledge about flexibility. However, flexibility remains largely abstraction domain, with term often meaning different things people....
This paper explores the improvements in manufacturing efficiency that can be achieved by broadening scope of production scheduling to include both sequencing work and coordination resource inputs required perform work. Recognizing some resources are inherently flexible thus reassigned dynamically processing centers as needed, job times often a function amount dedicated specific operations, we formulate flexible-resource problem with objective simultaneously determining permutation sequence,...
This paper investigates the improvements in manufacturing performance that can be realized by broadening scope of production scheduling function to include both job sequencing and processing-time control through deployment a flexible resource. We consider an environment which set jobs must scheduled over parallel cells, each consisting single machine, where processing time depends on amount resource allocated associated cell. Two versions problem are introduced: static resource-allocation...
Resource flexibility refers to the ability dynamically reallocate units of resource from one stage a production process another in response shifting bottlenecks. Recent research has demonstrated that substantial improvements operational performance can be realized both serial- and parallel-machine environments through effective utilization flexibility. In these contexts was assumed exhibit complete This explores extent which benefits associated with achieved flow shop environment using...
This aptitude-treatment interaction study classified 68 subjects as external or internal. Approximately half of the externals (internals) were given a traditional, teacher controlled method instruction, with remaining being involved in contract for grade plan. At conclusion an eight week course introductory psychology, all 75 item multiple choice achievement posttest. Analysis covariance was used to test hypothesis between I-E and instruction. A strong disordinal found, internals performing...
A critical decision facing firms across industries is the selection of a mix products to offer in marketplace. Both practice and academic literature, product line design problem has typically been considered from marketing perspective, with focus on how alternative sets interact compete The operational implications decisions have largely ignored, even while importance complexity interactions among manufacturing environment increase broadening lines. Furthermore, consideration synergies...
Abstract Interactions with managers in the automobile industry indicate that efforts to bring potentially profitable new technologies into production are often frustrated by traditional unit cost‐based approach is used for evaluating technologies. Opportunities timely introduction of valuable or even preemptive can be missed because cost comparisons, typically applied a limited set vehicle configurations volumes based on current demand figures, invariably favor incumbent over In this...
Mycobacteriophages – viruses of mycobacterial hosts are genetically diverse but morphologically all classified in the Caudovirales with double-stranded DNA and tails. We describe here a group five closely related mycobacteriophages Corndog, Catdawg, Dylan, Firecracker, YungJamal designated as Cluster O long flexible tails unusual prolate capsids. Proteomic analysis phage Corndog particles, Catdawg Corndog-infected cells confirms expression half predicted gene products indicates non-canonical...
Abstract A critical decision facing firms across industries is the selection of a mix products to offer in marketplace. Both practice and academic literature, product line design problem has typically been considered from marketing perspective, with focus on how alternative sets interact compete The operational implications decisions have largely ignored, even while importance complexity interactions among manufacturing environment increase broadening lines. Furthermore, consideration...
The tumor-derived GL261 cell line is used as a model for studying glioblastoma and other high-grade gliomas, can be cultured adherently or free-floating aggregates known neurospheres. These different culture conditions give rise to distinct phenotypes, with increased tumorigenicity displayed by neurosphere-cultured cells. An important technique understanding pathobiology live fluorescent imaging of intracellular calcium. However, neurospheres presents technical challenge, experimental...