A5024838255- Pancreatic function and diabetes
- Polyamine Metabolism and Applications
- Biopolymer Synthesis and Applications
- SARS-CoV-2 detection and testing
- RNA Interference and Gene Delivery
- Hydrogels: synthesis, properties, applications
- Advanced Drug Delivery Systems
- 3D Printing in Biomedical Research
- COVID-19 diagnosis using AI
- Respiratory viral infections research
- biodegradable polymer synthesis and properties
Shahid Beheshti University of Medical Sciences
2018-2021
In past decades, alginate-based multilayer microcapsules have been given important attention in various pharmaceutical investigations. Alginate-poly l lysine-alginate (APA) is studied the most. Due to similarity between structure of polyethyleneimine (PEI) and poly-L-lysine (PLL) also lower price PEI than PLL, this study was conducted compare efficacy linear (LPEI) branch (BPEI) forms with PLL as covering layers fabrication microcapsules. The were fabricated using electrostatic bead...
Purpose: Poly l-lysine (PLL) has been introduced as a strengthening covering layer for alginate microcapsules which are the most convenient way cell encapsulation. Some disadvantages of PLL such high price and low biocompatibility have prompted scientists to find better alternatives. Linear poly ethylene imine (LPEI), thanks its highly similar structure PLL, could be considered proper cost-effective alternative. In this study LPEI were compared layers cell-loaded alginate-LPEI-alginate...
Introduction: Microencapsulation technology is a valuable technique for protection and delivery of materials which cannot be administered alone due to their low solubility, volatility etc. A biopolymer alginate has been used most commonly as microcapsule forming material. In order increase the mechanical stability safety microcapsules, multilayered microcapsules are prepared. Alginate-poly l-lysine alginate, oldest microcapsule. Introducing another polycationic polymer similar properties...