A5064096911- Facial Trauma and Fracture Management
- Reconstructive Surgery and Microvascular Techniques
- Ferroptosis and cancer prognosis
- Phytochemistry and Bioactive Compounds
- Bone fractures and treatments
- Phytochemical Studies and Bioactivities
- Anatomy and Medical Technology
- Multiple Myeloma Research and Treatments
- Inflammation biomarkers and pathways
- Cancer Genomics and Diagnostics
- Seaweed-derived Bioactive Compounds
- Immune cells in cancer
- Oral and gingival health research
- Cancer Immunotherapy and Biomarkers
- Bone Tumor Diagnosis and Treatments
- interferon and immune responses
- Immunotherapy and Immune Responses
- AI in cancer detection
- Augmented Reality Applications
- Epigenetics and DNA Methylation
- Oral Health Pathology and Treatment
- Protein Degradation and Inhibitors
- Spectroscopy Techniques in Biomedical and Chemical Research
- Oral and Maxillofacial Pathology
- Metamaterials and Metasurfaces Applications
Heilongjiang University of Chinese Medicine
2025
Guangzhou University of Chinese Medicine
2023-2024
University of Hong Kong
2024
Chinese University of Hong Kong
2024
Peking Union Medical College Hospital
2022-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2023
Schematic illustration of the combinational strategy nanotechnology and PROTACs (Nano-PROTACs): typical shortcomings traditional nanotechnology-based strategies for PROTAC drugs optimization.
This work proposes a robot-assisted augmented reality (AR) surgical navigation system for mandibular reconstruction. The accurately superimposes the preoperative osteotomy plan of mandible and fibula into real scene. It assists doctor in quickly safely under guidance robotic arm.
Liver metastasis (LM) stands as a primary cause of mortality in metastatic colorectal cancer (mCRC), posing significant impediment to long-term survival benefits from targeted therapy and immunotherapy. However, there is currently lack comprehensive investigation into how senescent exhausted immune cells contribute LM.
Introduction T helper 17 (Th17) cells have a significant effect in the pathogenesis of asthma, and signal transducer activator transcription 3 (STAT3) pathway activation is critical for Th17 cell differentiation. Timosaponin A-III (TA3) was reported to inhibit STAT3 pathway. Here, we investigated whether TA3 improved asthma by inhibiting
Chronic obstructive pulmonary disease (COPD) is a prevalent lung that mainly induced by cigarette smoking (CS). Soyasaponin I an amphiphilic oleanane triterpenoid glycoside extracted form Astragali Radix. In order to investigate treatment strategies of COPD, this study focused on the effect soyasaponin tissue COPD model. The mouse model was CS exposure for 12 weeks, and administrated with different doses I. Subsequently, morphology histopathology tissue, proportion inflammatory cell, levels...
Oral cancer, a predominant malignancy in developing nations, represents global health challenge with five-year survival rate below 50%. Nonetheless, substantial reductions both its incidence and mortality rates can be achieved through early detection appropriate treatment. Crucial to these treatment plans prognosis predictions is the identification of pathological type oral cancer.Toward this end, fiber-optic Raman spectroscopy emerges as an effective tool. This study combines technology...
Oxeiptosis is a recently discovered caspase-independent, non-inflammatory programmed cell death modality. Current studies suggest that oxeiptosis has crucial effects on biological processes in variety of diseases. However, the mechanism hepatocellular carcinoma (HCC) remains unclear and no relevant have been published. Therefore, this study intended to investigate prognostic role oxeiptosis-related genes HCC. We explored mechanisms molecular phenotypes underlying HCC through multi-omics...
Calcifying Epithelial Odontogenic Tumor (CEOT), also known as Pindborg tumor, is a rare odontogenic benign tumor. It was first reported by Thoma and Goldman in 1946 defined an independent tumor 1957. Herein, we CEOT case involving most of the mandible after I-125 implantation 53-year-old man. We cooperated with governmental hospital departments to resect tumors, reconstruct fibular flap graft, properly dispose radioactive particles.
Abstract Background Mandibular defects can greatly affect patients' appearance and functionality. The preferred method to address this issue is reconstructive surgery using a fibular flap. current personalized guide plate improve the accuracy of osteotomy reconstruction, but there are still some problems such as complex design process time-consuming. Therefore, we modified conventional template serve dual purpose guiding mandible fibula facilitating placement pre-bent titanium. Methods was...
Distant metastasis is the leading cause of cancer-related mortality, and achieving survival benefits through advancements in systemic therapy remains challenging. Mast cells play a dual role shaping tumor microenvironment (TME) influencing distant metastasis, underscoring significant research value targeting mast for advanced cancer. We investigated variations cell infiltration levels primary metastatic malignancies using immunocyte analysis. subsets were identified from pan-cancer...