Hongtao Nie

ORCID: 0000-0003-2507-5204
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About
Contact & Profiles
Research Areas
  • Marine Bivalve and Aquaculture Studies
  • Physiological and biochemical adaptations
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • Genetic diversity and population structure
  • Invertebrate Immune Response Mechanisms
  • Aquatic Invertebrate Ecology and Behavior
  • Vibrio bacteria research studies
  • Calcium Carbonate Crystallization and Inhibition
  • Identification and Quantification in Food
  • Ocean Acidification Effects and Responses
  • MicroRNA in disease regulation
  • Meat and Animal Product Quality
  • Heat shock proteins research
  • Chromosomal and Genetic Variations
  • Fish Biology and Ecology Studies
  • Fish Ecology and Management Studies
  • Cancer-related molecular mechanisms research
  • Genomics and Phylogenetic Studies
  • Evolution and Genetic Dynamics
  • Marine Biology and Environmental Chemistry
  • Marine Ecology and Invasive Species
  • Reproductive biology and impacts on aquatic species
  • Marine Biology and Ecology Research
  • Protein Hydrolysis and Bioactive Peptides

Dalian Ocean University
2016-2025

Auburn University
2018

Shell (United Kingdom)
2018

Shell (Netherlands)
2016

Ocean University of China
2009-2014

Ruditapes philippinarum is an economically important bivalve with remarkable diversity in its shell coloration patterns. In this study, we sequenced the whole genome of Manila clam and investigated molecular basis adaptation to hypoxia, acidification, parasite stress transcriptome sequencing RNA sequence analysis different tissues developmental stages clarify these major issues. A number immune-related gene families are expanded R. genome, such as TEP, C3, C1qDC, Hsp70, SABL, lysozyme, which...

10.1016/j.isci.2019.08.049 article EN cc-by-nc-nd iScience 2019-08-30

Abstract Background Hypoxia is an important environmental stressor in aquatic ecosystems, with increasingly impacts on global biodiversity. Benthic communities are the most sensitive parts of coastal ecosystem to eutrophication and resulting hypoxia. As a filter-feeding organism living seafloor sediment, Ruditapes philippinarum represents excellent “sentinel” species assess quality marine environment. In order gain insight into molecular response acclimatization mechanisms hypoxia stress...

10.1186/s12864-020-6734-6 article EN cc-by BMC Genomics 2020-04-23

The metabolic responses of different colour strains Ruditapes philippinarum in terms oxygen consumption and ammonia excretion to changes temperature (15–35°C) salinity (20–40) were investigated. In our range temperatures (15–35°C), rate (OCR) increases cultivated (White Zebra) opposition the effect wild strain which reach a maximum at 25°C. highest Q10 coefficients 2.741 for zebra strain, 4.326 white 1.944 25–30, 30–35 20–25°C respectively. (20–40°C), OCRs firstly decreased lowest level 25...

10.1111/are.13111 article EN Aquaculture Research 2016-07-25

Bivalve mollusks are economically important invertebrates that exhibit marked diversity in benthic lifestyle and provide valuable resources for understanding the molecular basis of adaptation to life. In this report, we present a high-quality, chromosome-anchored reference genome Venus clam, Cyclina sinensis. The chromosome-level was assembled by Pacific Bioscience single-molecule real-time sequencing, Illumina paired-end 10× Genomics, high-throughput chromosome conformation capture...

10.1016/j.isci.2020.101148 article EN cc-by iScience 2020-05-11

The clam Ruditapes philippinarum is an important species in the marine aquaculture industry China. However, recent years, of R. has been negatively impacted by various bacterial pathogens. In this study, transcriptome libraries showing different levels resistance to challenge with Vibrio anguillarum were constructed and RNA-seq was performed using Illumina sequencing platform. Host immune factors identified that responded V. infection, including C-type lectin domain, glutathione...

10.3389/fimmu.2022.879337 article EN cc-by Frontiers in Immunology 2022-05-09

Ruditapes philippinarum, is an economically important marine bivalve species. The ability to cope with low salinity stress quite for the survival of aquatic species under natural conditions. In this study, transcriptional response Manila clam was characterized using RNA sequencing. transcriptomes a salinity-treatment group (FRp1, FRp2), which survived stress, and control (SRp1, SRp2), not subjected were sequenced Illumina HiSeq platform. A total 196,578 unigenes generated. GO KEGG analyses...

10.1038/s41598-017-05397-8 article EN cc-by Scientific Reports 2017-07-04

Genetic linkage maps are indispensable tools in a wide range of genetic and genomic research. With the advancement genotyping-by-sequencing (GBS) methods, construction high-density has become achievable marine organisms lacking sufficient resources, such as mollusks. In this study, map was constructed for an ecologically commercially important clam species, Ruditapes philippinarum. For consensus map, total 9658 markers spanning 1926.98 cM were mapped to 18 sex-averaged groups, with average...

10.1038/s41598-017-00246-0 article EN cc-by Scientific Reports 2017-03-13

Abstract Background Manila clam ( Ruditapes philippinarum ) is a worldwide commercially important marine bivalve species. In recent years, however, microbial diseases caused high economic losses and have received increasing attention. To understand the molecular basis of immune response to pathogen-associated patterns (PAMPs) in R. , transcriptome libraries hepatopancreas were constructed at 24 h post-injection with Lipopolysaccharide (LPS), peptidoglycan (PGN), polyinosinic-polycytidylic...

10.1186/s12864-020-06914-2 article EN cc-by BMC Genomics 2020-08-01

10.1016/j.cbd.2025.101426 article EN Comparative Biochemistry and Physiology Part D Genomics and Proteomics 2025-01-01
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