Abstract Abnormally formed FUS/EWS/TAF15 (FET) fusion oncoproteins are essential oncogenic drivers in many human cancers. Interestingly, at the molecular level, they also form biomolecular condensates specific loci. However, how these lead to gene transcription and features encoded DNA element regulate condensate formation remain unclear. Here, we develop an vitro single-molecule assay visualize phase separation on DNA. Using this technique, observe that FET proteins undergo target binding...

In this paper, a multichannel refractive index sensor based on subwavelength metal–insulator–metal (MIM) waveguide coupled with tangent-ring resonators is proposed. When two were placed above the MIM waveguide, Fano resonance asymmetrical line shape appeared in transmission spectrum due to interference between light–dark resonant modes. The sensitivity and figure of merit as high 880 nm/RIU 964, respectively. Through adding more resonators, multiple resonances ultrasharp peaks/dips achieved...

In this paper, an end-coupled hexagonal resonator inserted with dual parallel metallic blocks is proposed based on subwavelength metal-insulator-metal waveguides. When the are vertically into resonator, more transmission channels (three peaks) symmetrical spectral shapes than that (one peak) of perfect achieved in same wavelength range. The peaks all have high transmittances; thus, structure can be performed as on-chip optical filter. horizontally distributed antinode and node magnetic field...

A graphene-based metamaterial structure, consisting of a graphene strip (GS) and L-shaped graphene-rectangular block (GRB), is proposed to generate the plasmon-induced transparency (PIT) effect. The potential physical properties PIT effect are analyzed by using coupled mode theory (CMT). has unique characteristics controlling light propagation through static dynamic regulations, resulting in prospective switching application. performance optical switch evaluated different parameters,...

To evaluate the prognostic and molecular mechanisms of sex racial differences in gastric cancer, data from two large centers were used to retrospectively analyze survival cancer patients with regard differences. In examining mechanism different races, The Cancer Genome Atlas database differentially expressed genes (DEGs), Gene Ontology (GO) enrichment DNA methylation analyses performed. Among White patients, it was found that prognosis for females better than males; conversely, among Chinese...

Abstract In this research, a metamaterial structure composed of graphene sandwich is put forward to achieve triple plasmon-induced transparency. This phenomenon generated by bright–bright modes interaction in the proposed structure, and results calculated though couple mode theory are consistent with simulation ones using finite difference time domain method. addition, effects Fermi level scattering rate on transmission spectrum also discussed. It found that five-fold switching achieved...

The proportion of soluble components in dietary fiber is an important factor affecting its physicochemical properties and physiological functions. influence mechanisms insoluble (IDF) (SDF) at different ratios on constipation were investigated. Results showed that SDF had higher active groups water swelling capacity than IDF. viscosity chyme with alone was the highest oral gastric phases. emptying rate small intestine propulsion increased significantly, especially when IDF/SDF 1:1. IDF a...

Abstract Plasmon-induced transparency (PIT) is theoretically explored for a graphene metamaterial using finite-difference time-domain numerical simulations and coupled-mode-theory theoretical analysis. In this work, the proposed structure consists of one rectangular cavity three strips to generate PIT phenomenon. The window can be regulated dynamically by adjusting Fermi level graphene. Importantly, modulation depth amplitude reach 90.4%. refractive index sensitivity also investigated,...

A multi-channel Fano resonant structure is proposed and analyzed based on subwavelength metal–insulator–metal (MIM) waveguides. First, two MIM output ports associated with specific side-coupled cavities are designed to locate at the center quarter positions of an end-coupled cavity, respectively. Since interference between dark bright modes, dual-channel resonances asymmetrical lines shapes obtained both ports, High sensitivity figure merits investigated. Besides, phase shifts also...

A type of coupled plasmonic resonant system using a metal–insulator -metal (MIM) waveguide is proposed and investigated for generating multiple Fano resonances in this paper. The multi-mode interference coupled-mode theory (MICMT) mainly employed to analyze the theoretically, these results agree well with numerically obtained finite-difference time-domain (FDTD) method. In system, asymmetrical Fano-resonant peaks are achieved spectra by employing two waveguides separated metallic baffle...

Abstract In this paper, a sub-wavelength metal-insulator-metal (MIM) waveguide structure is proposed by using cross-shape rectangular cavity, of which wings are coupled with two cavities. Firstly, cavity placed between the input and output MIM waveguides. According to mutual interference bright dark modes, three Fano resonant peaks generated. Secondly, adding on left wing cross shaped one, five asymmetric resonance obtained. Thirdly, six achieved after another right wing. Finally,...

We have theoretically investigated a plasmonic metal-dielectric-metal (MDM) resonant system with water-based dielectric, which allow easy implementation of up to eight Fano channels. The reported MDM is composed by an end-coupled square ring and three reversed L-shape cavities, can support bright modes or dark that will interact each other generate sharp asymmetric profiles in transmission spectra. Finite-difference time-domain (FDTD) method multiple interference coupled mode theory (MICMT)...

The key role of enzymatic hydrolysis and fermentation in the sensory quality set yogurt made from whole oats was demonstrated. optimal process established by orthogonal response surface methodology based on acidity, textural, rheological properties. results indicated that appropriately consisted liquefaction with 12 U/mL α-amylase at 70 °C pH 6.5 for 60 min, followed saccharification 400 α-1,4-glucan glucohydrolase 4.5 min. Streptococcus thermophilus ST15 Lactobacillus bulgaricus 20249...

Extruded noodles made from whole Tartary buckwheat are widely known as healthy staple foods, while the treatment of fresh after extrusion is crucial. The difference in sensory and functional quality between frozen (FTBN) hot air-dried (DTBN) was investigated this study. results showed a shorter optimum cooking time (FTBN 7 min vs. DTBN 17 min), higher hardness (8656.99 g 5502.98 g), less loss (5.85% 21.88%) treated by freezing rather than air drying, which corresponded to better (an overall...

Firstly, in this paper, the proposed structure is composed of a transverse graphene rectangular cavity and vertical cavity, so as to produce plasmon-induced transparency (PIT) phenomenon. The PIT metamaterials theoretically explored by using finite-difference time-domain (FDTD) simulation coupled-mode-theoretical (CMT) analysis. Then, adjusting Fermi level graphene, window dynamically adjusted, that can be used an optical switch. Furthermore, refractive index sensitivity investigated results...