A5027355657- Marine and coastal plant biology
- Neuroscience and Neuropharmacology Research
- Marine Biology and Ecology Research
- Neural dynamics and brain function
- Insect and Arachnid Ecology and Behavior
- Sperm and Testicular Function
- Algal biology and biofuel production
- Coastal wetland ecosystem dynamics
- Marine and coastal ecosystems
- Neurobiology and Insect Physiology Research
- Retinal Development and Disorders
- Plant and animal studies
- Photoreceptor and optogenetics research
- Lepidoptera: Biology and Taxonomy
- Seaweed-derived Bioactive Compounds
- Insect Pheromone Research and Control
- Neuroscience and Neural Engineering
- Reproductive Biology and Fertility
- Physiological and biochemical adaptations
- Biocrusts and Microbial Ecology
- Marine Biology and Environmental Chemistry
- Reproductive Physiology in Livestock
- Animal Behavior and Reproduction
- Visual perception and processing mechanisms
- Plant Reproductive Biology
Israel Oceanographic and Limnological Research
1999-2024
Royal Hospital for Women
2024
UNSW Sydney
2024
Baylor College of Medicine
2007-2024
Virginia Tech
2013-2024
Carilion Clinic
2011-2024
Biomedical Research Institute
2020-2024
Virginia Department of Health
2022
Sacred Heart Medical Center
2020
Harvard University
2011
L-Glutamate and norepinephrine are examples of a major excitatory neurotransmitter neuromodulator in the cerebral cortex, respectively. Little is known how chemical signaling between anatomically distinct pathways occurs. Specific activation N -methyl-D-aspartate (NMDA) class glutamate receptor synaptosomal preparations from guinea pig cortex caused release both these chemicals, this was blocked by agents that inhibit nitric oxide (NO) production or remove NO extracellular space....
The last several decades have seen a large increase in knowledge of the underlying biological mechanisms that serve learning and memory. insights gleaned from neurobiological cognitive neuroscientific experimentation humans animal models identified many processes at molecular, cellular, systems levels occur during formation, storage, recall memories. Moreover, with advent noninvasive technologies to monitor patterns neural activity various forms human cognition, efficacy different strategies...
ABSTRACT The spindle of metazoan cells functions as a dual distributor that guarantees the accurate segregation both chromosomes and centnoles (basal bodies). This combined mechanism may have evolved from separate distribution devices for basal bodies found in Protozoa. Typical eupyrene spermatocytes silk moth were compared with atypical apyrene spermatocytes. (a) Long microtubules, persisting during centnolar movements, develop meiotic prophases continuity centrtoles (b) There is no longer...
Recent national reports and commentaries on the current status needs of U.S. biomedical research workforce have highlighted limited career development opportunities for predoctoral postdoctoral trainees in academia, yet little attention is paid to preparation pathways outside traditional faculty path. Recognizing this issue, 2013, National Institutes Health (NIH) Common Fund issued a request application titled "NIH Director's Biomedical Research Workforce Innovation Award: Broadening...
Efficiency of synaptic transmission within the neocortex is regulated throughout life by experience and activity. Periods correlated or uncorrelated presynaptic postsynaptic activity lead to enduring changes in efficiency [long-term potentiation (LTP) long-term depression (LTD), respectively]. The initial plasticity triggering event thought be a precipitous rise intracellular calcium, with higher levels inducing LTP more moderate LTD. We used pairing protocol visual cortical brain slices...
Vision in most vertebrates is an active process that requires the brain to combine retinal signals with information about eye movement. Eye movement may feed forward from motor control areas of or back extrinsic muscles. Feedback elicited by passive selectively gate outflow at first relay, dorsal lateral geniculate nucleus. The gating predominantly facilitates retinogeniculate transmission immediately after and inhibits when a new steady-state position achieved. These two effects are...
Horseradish peroxidase injected into 18 single, physiologically identified geniculate X and Y cells permitted a detailed morphological correlate to be determined for the physiological properties of each neuron. Class 1 characteristics were associated with cells, class 3 2 structural traits seen in both types.
Abstract Both typical (haploid) and atypical (anucleated) spermatozoa reach the receptaculum seminis of inseminated females Bombyx mori intermingled. However, only both leave fertilize eggs. Atypical spermatozoa, which are in fact anucleated flagellar apparatuses, probably function transporting fertilizing to seminis. In male ejaculatory duct kinds wrapped with extra‐cellular sleeves that presumably protect them on their way receptaculum. Typical “hatch” from before leaving The presence a...
PURPOSE Lenvatinib plus pembrolizumab (len + pembro) significantly improved progression-free survival (PFS) and overall (OS) versus chemotherapy in previously treated advanced or recurrent endometrial cancer (aEC) the phase III Study 309/KEYNOTE-775. We report results from III, randomized, open-label European Network of Gynaecological Oncological Trial-en9/LEAP-001 study (ClinicalTrials.gov identifier: NCT03884101 ) that evaluated len pembro first-line aEC. METHODS Patients with stage to IV...
Gracilaria conferta (Schousboe ex Montagne) J. et G. Feldmann responded with an oxidative burst and rapid increases in respiration halogenating activity when agar, agarose, or the agarose degradation products neoagarotetraose neoagarohexaose were added to growth medium. In contrast, carrageenan, oligocarrageenans, neoagarobiose, l‐galactose, d‐galactose, several other mono‐ oligosaccharides did not have any effect. Sixfold observed 3 min after addition of neoagarohexaose. The response could...
Elicitation of Gracilaria conferta (Schousboe ex Montagne) J. et G. Feldmann with oligoagars resulted in a defense response that was strong enough to kill epiphytic bacteria associated the alga. Up 60% resident bacterial flora healthy plants eliminated within 60 min after addition neoagarohexaose algal medium. Single isolates agar‐degrading had been isolated previously from or decaying tissues proved be more sensitive. Some them were generally unable survive on conferta. Others survived...
Abstract Transient contributions of subplate neurons to the initial development cortex are well‐characterized, yet little data available on a subpopulation that persist in white matter (WM) cerebral across development. To characterize WM neurons, differential interference contrast and Nomarski optics were used visualize individual cells slices rat visual at postnatal ages 9–23. Soma‐dendritic morphology local axonal projection patterns, including probable synaptic innervation sites their...
Subplate (SP) neurons are important for the proper development of thalamocortical innervation. They necessary formation ocular dominance and orientation columns in visual cortex. During perinatal period, many SP die. The surviving cohort forms interstitial cells white matter (WM) a band horizontally oriented below layer VI (layer VIb, VII, or subplate cells). Although function embryonic has been well established, functional roles WM postnatal not known. We used combination anatomical,...
Abstract The typical eupyrene and atypical apyrene cycles of sperm differentiation in Bombyx mori were studied, with special attention to centriole number behavior. Contrary other reports, there is always only one the differentiating mature sperm, thus confirming our previous findings that insect has at base flagellum, contrast two centrioles found many groups animals. This numerical difference discussed an evolutionary context.
Serum albumin was shown to stimulate markedly various photoreactions in isolated bean and lettuce chloroplasts. The maximal effect obtained when this compound present during the homogenization step continuously chloroplast preparation. "basal" electron transport enhanced using acceptors stimulation also presence of uncouplers. quantum requirement for ferricyanide reduction appreciably reduced. increased rate cyclic phosphorylation ratio P/e(2) non-cyclic phosphorylation. increase is...