Pedro Filho Noronha Souza

ORCID: 0000-0003-2524-4434
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Biochemical and Structural Characterization
  • SARS-CoV-2 and COVID-19 Research
  • Protein Hydrolysis and Bioactive Peptides
  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Plant Virus Research Studies
  • Transgenic Plants and Applications
  • Peptidase Inhibition and Analysis
  • Phytochemical compounds biological activities
  • Probiotics and Fermented Foods
  • Plant-Microbe Interactions and Immunity
  • Agricultural pest management studies
  • Bacteriophages and microbial interactions
  • Mosquito-borne diseases and control
  • Toxin Mechanisms and Immunotoxins
  • Plant Parasitism and Resistance
  • Legume Nitrogen Fixing Symbiosis
  • Cancer Mechanisms and Therapy
  • Viral Infections and Vectors
  • Carbon and Quantum Dots Applications
  • Viral gastroenteritis research and epidemiology
  • Nail Diseases and Treatments
  • Colorectal Cancer Treatments and Studies
  • Essential Oils and Antimicrobial Activity

Universidade Federal do Ceará
2016-2025

Universidade de Ribeirão Preto
2025

Universidade de São Paulo
2025

Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico
2024-2025

University of Nebraska–Lincoln
2018-2021

Potyviruses (family Potyviridae, genus Potyvirus) are the result of an initial radiation event that occurred 6,600 years ago. The currently consists 167 species infect monocots or dicots, including domesticated and wild plants. transmitted in a non-persistent way by more than 200 aphids. As indicated their wide host range, worldwide distribution, diversity vectors, potyviruses have outstanding capacity to adapt new hosts environments. However, factors confer adaptability poorly understood....

10.3389/fpls.2019.01439 article EN cc-by Frontiers in Plant Science 2019-11-12

The emergence of antibiotic-resistant microbes has stimulated research worldwide seeking new biologically active molecules. In this respect, synthetic antimicrobial peptides (SAMPs) have been suggested to overcome problem. Although there are some online servers that provide putative SAMPs from protein sequences, the choice best peptide sequences for further analysis is still difficult. Therefore, goal paper not launch a tool but friendly workflow characterize and predict potential by...

10.1016/j.biochi.2020.05.016 article EN publisher-specific-oa Biochimie 2020-06-11

Abstract Fungal infections cause more than 1.5 million deaths a year. Due to emerging antifungal drug resistance, novel strategies are urgently needed combat life-threatening fungal diseases. Here, we identify the host defense peptide mimetic, brilacidin (BRI) as synergizer with caspofungin (CAS) against CAS-sensitive and CAS-resistant isolates of Aspergillus fumigatus, Candida albicans , C. auris CAS-intrinsically resistant Cryptococcus neoformans . BRI also potentiates azoles A. fumigatus...

10.1038/s41467-023-37573-y article EN cc-by Nature Communications 2023-04-12

Chitosan is a cationic polysaccharide derived from chitin deacetylation. This and its oligosaccharides have many biological activities can be used in several fields due to their favorable characteristics, such as biodegradability, biocompatibility, nontoxicity. review aims explore the antifungal potential of chitosan chitooligosaccharides along with conditions for activity mechanisms action they use kill fungal cells. The sources, chemical properties, applications are discussed this review....

10.1002/cbdv.202400044 article EN Chemistry & Biodiversity 2024-04-09

Candida albicans has emerged as a major public health problem in recent decades. The most important contributing factor is the rapid increase resistance to conventional drugs worldwide. Synthetic antimicrobial peptides (SAMPs) have attracted substantial attention alternatives and/or adjuvants therapeutic treatments due their strong activity at low concentrations without apparent toxicity. Here, two SAMPs, named Mo ‐CBP 3 ‐PepI (CPAIQRCC) and ‐PepII (NIQPPCRCC), are described, bioinspired by...

10.1002/psc.3249 article EN Journal of Peptide Science 2020-03-18

Introduction. There is growing concern about infections caused by non-albicans Candida species, including species of the parapsilosis complex - which have seen a considerable increase in cases during COVID-19 pandemic addition to nematode resistance currently used anthelmintics.Gap Statement. Lupeol triterpenoid phytosterol that has wide range biological activities, although its antifungal and antiparasitic potential still poorly explored. Additionally, effect on biofilm C. not yet been...

10.1099/jmm.0.001976 article EN Journal of Medical Microbiology 2025-03-07
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