A5045691613- Essential Oils and Antimicrobial Activity
- Antifungal resistance and susceptibility
- Antimicrobial Peptides and Activities
- Phytochemistry Medicinal Plant Applications
- Polysaccharides Composition and Applications
- Biochemical and Structural Characterization
- Pineapple and bromelain studies
- Complementary and Alternative Medicine Studies
- Piperaceae Chemical and Biological Studies
- Insect Resistance and Genetics
- Phytochemical compounds biological activities
- Cardiac electrophysiology and arrhythmias
- Streptococcal Infections and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Eosinophilic Esophagitis
- Acute Kidney Injury Research
- Takotsubo Cardiomyopathy and Associated Phenomena
- Nanocomposite Films for Food Packaging
- Moringa oleifera research and applications
- HIV/AIDS drug development and treatment
- Amoebic Infections and Treatments
- Postharvest Quality and Shelf Life Management
- Adrenal and Paraganglionic Tumors
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
Universidade Federal do Ceará
2017-2025
Hospital de Egas Moniz
2013-2015
Hospital of St. Francis Xavier
2013
A trypsin inhibitor from Cassia leiandra seeds, named ClTI, was purified, characterized, and its insecticidal activity against Aedes aegypti evaluated. ClTI purified by DEAE-Cellulose trypsin-Sepharose 4B chromatography, with a 15.5-fold purification 2.4% yield. is composed of 19,484 Da polypeptide chain as revealed mass spectrometry, it not glycoprotein, amino acid sequence similar to other Kunitz-type inhibitors, comprises 35% β-sheets, 14% β-turns, 50% disordered secondary structures. an...
The fixed oil from the inner mesocarp of Caryocar coriaceum Wittm. is used in Chapada do Araripe region Brazil for treatment genitourinary candidiasis. This study aimed to evaluate chemical composition, antifungal activity, reduction fungal virulence, and preliminary toxicity C. tested against three Candida yeasts. was characterized by gas chromatography (GC-MS GC-FID). Antifungal activity assessed using serial microdilution method. Additionally, potential as an enhancer fluconazole action...
With improvements in survival and disease progression the era of combined antiretroviral therapy, complications such as kidney are becoming increasingly prevalent HIV-infected patients. Tenofovir disoproxil fumarate (TDF) has been associated with nephrotoxicity, including decline glomerular filtration rate, proximal tubular damage acute injury.Characterize safety TDF-containing treatment (ART) regimens patients.Non-controlled, observational, retrospective study was based on clinical files...
Introduction . Calcium channel blockers (CCBs) drugs are widely used in the treatment of cardiovascular diseases. CCB poisoning is associated with significant toxicity and potentially fatal. Currently, there no specific antidote supportive; however, this supportive therapy often insufficient. We present a clinical case severe diltiazem therapeutic approaches that were used. Case Report A 55-year-old male was admitted to intensive care unit (ICU) after voluntary multiple drug intake,...
Purpose. To report a case of successful thrombolysis performed in patient with an incidental unruptured intracranial aneurysm and review the literature. Case Report. Patient admitted for ischemic stroke due to left posterior cerebral artery occlusion, right middle aneurysm, who underwent treatment tissue plasminogen activator (rtPA) resulting clinical improvement without complications. Conclusion. The presence aneurysms is considered as contraindication thrombolysis, potentially higher...
We report a case of 74-year-old man who presented to the emergency department with 1-week history fever. He had meatal stenosis and suprapubic catheter for 10 months, recent hospitalisation urosepsis bacteraemia due methicillin-resistant Staphylococcus aureus after manipulation catheter. Clinical examinations were performed in patient was hospitalised diagnosis recurrent urinary tract infection. The following day, we noticed development mass left sternoclavicular joint inflammatory signs...
Introduction: Clinic infections caused by various microorganisms are a public health concern. The rise of new strains resistant to traditional antibiotics has exacerbated the problem. Thus, search for antimicrobial molecules remains highly relevant. Methods: current study purified, characterized, and assessed activity papain inhibitor from Terminalia catappa L. seeds. Results: was purified heating crude extract at 80°C 30 min, followed ion exchange chromatography on DEAE cellulose column....
<title>Abstract</title> The incidence of <italic>Candida</italic> species resistance to traditional antifungals is increasing globally. This issue significantly impacts patients' lives and raises healthcare expenses, confirming the need for developing novel therapeutic strategies. Recently, a thermostable trypsin inhibitor was isolated from <italic>Salvia hispanica</italic> L. (chia) seeds – named ShTI (MM 11.558 kDa) with an antibacterial effect against <italic>Staphylococcus...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
IntroducaoA pneumonia eosinofilica (PE) enquadra-se num grupo heterogeneo de doencas caracterizadas pela presenca eosino?los a nivel pulmonar, associado in?ltrados. A etiologia e variada, sendo subdividida em causas primarias (idiopatica) secundarias. PE cronica idiopatica uma entidade rara, mais frequente mulheres na 4a 5a decada vida, que maioria dos doentes nao sao fumadores.
Abstract The emergence of antibiotic resistance poses a serious and challenging threat to healthcare systems, making it imperative discover novel therapeutic options. This work reports the isolation characterization thermostable trypsin inhibitor from chia (Salvia hispanica L.) seeds, with antibacterial activity against Staphylococcus aureus sensitive resistant methicillin. ShTI was purified seeds through crude extract heat treatment, followed by affinity reversed-phase chromatography....