A5015895355- Morinda citrifolia extract uses
- Bioactive Compounds and Antitumor Agents
- Essential Oils and Antimicrobial Activity
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Bioactive Compounds
- Science and Education Research
- Pineapple and bromelain studies
- Studies on Chitinases and Chitosanases
- Education Pedagogy and Practices
- Moringa oleifera research and applications
- Protein Hydrolysis and Bioactive Peptides
- Polysaccharides Composition and Applications
- Nematode management and characterization studies
- Toxin Mechanisms and Immunotoxins
- Oral health in cancer treatment
- Insect Resistance and Genetics
- Agricultural and Food Sciences
- Enzyme Catalysis and Immobilization
- Enzyme Production and Characterization
- Rural Development and Agriculture
- Algal biology and biofuel production
- Sesquiterpenes and Asteraceae Studies
- Transgenic Plants and Applications
- Chemotherapy-induced organ toxicity mitigation
- Hibiscus Plant Research Studies
Universidade Federal do Ceará
2016-2025
Universidade Estadual do Ceará
2012-2013
Abstract A thermostable chitin‐binding protein (14.3 kDa) with antifungal activity was isolated from Moringa oleifera seeds by affinity chromatography on chitin followed ion exchange chromatography. NH 2 ‐CPAIQRCCQQLRNIQPPCRCCQ ( Mo ‐CBP 3 ) is a glycoprotein 2.5% sugar, pI 10.8, without hemagglutination, chitinase or β‐glucanase activities. possesses in vitro against the phytopathogenic fungi Fusarium solani, F. oxysporum, Colletotrichum musae and C. gloesporioides . Contrarily, did not...
Abstract Croton zehntneri, a plant native to northeastern Brazil, is widely used in folk medicine treat gastrointestinal problems and has rich essential oil content. The effects of the zehntneri (EOCZ) its main constituent anethole on several models gastric lesions were studied mice rats. Oral treatment with EOCZ anethole, both at doses 30–300 mg/kg, caused similar dose‐dependent gastroprotection against ethanol‐ indomethacin‐induced damage, but did not change cold‐restraint stress‐induced...
Several studies have described the effects of seed exudates against microorganisms, but only few them investigated proteins that defensive activity particularly nematode parasites. This study focused on released in soybean seeds and evaluated their nematicidal properties Meloidogyne incognita. A proteomic approach indicated existence 63 exuded proteins, including β-1,3-glucanase, chitinase, lectin, trypsin inhibitor, lipoxygenase, all which are related to plant defense. The presence some...
Moringa oleifera Lam. is a perennial multipurpose tree that has been successfully used in folk medicine to cure several inflammatory processes. The aim of this study was purify and characterize chitin-binding protein from seeds, named Mo-CBP4, evaluate its antinociceptive anti-inflammatory effects vivo. purified by affinity chromatography on chitin followed ion exchange chromatography. Acetic acid-induced abdominal constrictions assay for the activity assessments. Mo-CBP4 glycoprotein (2.9%...
This study optimizes the pyrodextrinization of yam (Dioscorea sp.) starch isolated from tubers grown in Brazil to produce a yellow pyrodextrin with lowest enzymatically available (AS) content and color difference (ΔE) index. At 140 °C (fixed heating temperature), effects acid concentration (0.65 − 2.99 g HCl/kg starch) incubation time (53 307 min) on response variables were evaluated using surface methodology. Some physicochemical characteristics also determined pyrodextrins. Both factors...
Soybean toxin (SBTX) is a 44 kDa glycoprotein that lethal to mice (LD50 = 5.6 mg/kg). This study reports the toxicity of SBTX on pathogenic fungi and yeasts mechanism its action. inhibited spore germination Aspergillus niger Penicillium herguei was toxic Candida albicans, parapsilosis, Kluyveromyces marxiannus, Pichia membranifaciens, Saccharomyces cerevisiae. In addition, hampered growth C. albicans K. marxiannus glucose-stimulated acidification incubation medium by S. cerevisiae,...
Among the Bauhinia species, B. cheilantha stands out for its seed protein content. However, there is no record of nutritional value, being used in a nonsustainable way folk medicine and large-scale extraction timber. The aim this study was to investigate food potential seeds with emphasis on quality provide support flora conservation use as raw material or prototype development bioproducts high added socioeconomic value. show content (35.9%), reasonable essential amino acids profile, low...
Hyptis crenata, commonly known as "salva-do-Marajó", "hortelã-do-campo", and "hortelãzinha", is used in folk medicine Northeast Brazil tea or infusion to treat inflammatory diseases. Due the pharmacological efficacy low toxicity of essential oil crenata (EOHc), we decided investigate EOHc antiedematogenic effect experimental models inflammation. was administrated orally at doses 10-300 mg/kg male Swiss albino mice. Paw edema induced by subcutaneous injection right hind paw stimuli...
Spirulina platensis is a cyanobacterium with high protein content and presenting neuroprotective effects. Now, we studied protein-enriched fraction (SPF), on behavior, neurochemical immunohistochemical (IHC) assays in hemiparkinsonian rats, distributed into the groups: SO (sham-operated), 6-hydroxydopamine (6-OHDA), 6-OHDA (treated SPF, 5 10 mg/kg, p.o., 15 days). Afterward, animals were subjected to behavioral tests euthanized, brain areas used for IHC assays. SPF partly reversed changes...
Natural intoxication of livestock by ingestion Ipomoea asarifolia leaves has been reported to occur widely in Brazil. Previous studies carried out our research group provided strong evidence that a lectin could be involved with the toxic properties I. asarifolia. To reinforce this hypothesis, lectin-enriched fraction (LEF) was isolated from and its effects were assessed. Leaves excised plants growing field, mechanically wounded maintained chamber at 25 ± 3 °C for 72 h dark, under near 100%...
Soybean toxin (SBTX) is an antifungal protein from soybeans with broad inhibitory activity against the growth and filamentation of many fungi, including human plant pathogenic species such as Candida albicans, parapsilosis, Aspergillus niger, Penicillium herquei, Cercospora sojina kikuchii. Understanding mechanism by which SBTX acts on fungi yeasts may contribute to design novel drugs and/or development transgenic plants resistant pathogens. To this end, polymorphic yeast C. albicans was...