A5063886324- Phytochemistry and Bioactive Compounds
- Protein Hydrolysis and Bioactive Peptides
- Phytochemical compounds biological activities
- Drug-Induced Hepatotoxicity and Protection
- Pineapple and bromelain studies
- Plant biochemistry and biosynthesis
- Phytochemistry Medicinal Plant Applications
- Natural product bioactivities and synthesis
- Mosquito-borne diseases and control
- Seaweed-derived Bioactive Compounds
- Agricultural and Food Sciences
- Viral Infections and Vectors
- Oral and gingival health research
- Phytochemistry and Bioactivity Studies
- Insect Resistance and Genetics
- Insect Pest Control Strategies
- Oral microbiology and periodontitis research
- Environmental Sustainability and Education
- Inflammatory Bowel Disease
- Enzyme Production and Characterization
- Proteins in Food Systems
- Marine Sponges and Natural Products
- Toxin Mechanisms and Immunotoxins
- Entomopathogenic Microorganisms in Pest Control
- Academic Research in Diverse Fields
Universidade Federal do Piauí
2015-2025
Centro Universitário FEI
2024
Universidade de Taubaté
2024
Universidade Federal do Delta do Parnaíba
2020-2023
Universidade Federal do Amazonas
2021
Universidade Estadual do Piau
2017
Universidade Federal do Ceará
2004-2016
Universidade de Brasília
2006-2008
Universidade Federal de Minas Gerais
1999-2008
Pontifícia Universidade Católica do Rio Grande do Sul
2007
The aim of this study was to investigate whether experimental periodontitis cause changes the renal tissues and imbalance in oxidative stress kidneys.Twenty-two female Wistar rats were separated into two groups: control periodontitis. We assessed following parameters: gingival bleeding index (GBI), tooth mobility, gum malondialdehyde (MDA), myeloperoxidase (MPO) activity, probing pocket depth (PPD), alveolar bone loss (ABL) for periodontal tissues; histomorphometric measures associated with...
Damage caused by periodontitis not only affects periodontal tissues, but also increases the severity of various illnesses such as rheumatoid arthritis, diabetes, and liver diseases. The aim this study is to investigate association between induced damage through its systemic effects on liver.Twenty rats were divided into two groups: control periodontitis. following parameters evaluated: gingival bleeding index (GBI), probing depth (PD), myeloperoxidase (MPO) activity, alveolar bone loss (ABL)...
Latex from Calotropis procera is widely used in folk medicine as a rich source of biologically active compounds capable promoting diverse benefits such control dermal fungal infections, antimicrobial activities and pain relief among other useful properties. The aim this work was to characterize the anti-inflammatory effect non-dialysable protein fraction recovered rubber-free latex using three different experimental models when administrated intravenously. In vivo neutrophil migration...
Background and Objective Periodontitis may promote harmful systemic effects such as changes in hepatic tissues. The purpose of this study was to investigate whether the steatosis oxidative stress caused by experimental periodontitis are reversible liver. Material Methods Twenty‐four rats were divided into three groups: control, P20‐20 (20 days with 20 without periodontitis, verify reversibility injuries). following parameters assessed: gingival bleeding index, probing pocket depth,...
A Plumeria pudica produz um látex rico em proteínas (PLPp) com propriedades anti-inflamatórias, antinociceptivas e antidiarreicas, além de reduzir a periodontite atuar como protetor na colite ulcerativa. O presente estudo teve objetivo avaliar os efeitos das do mucosite intestinal induzida por 5-fluorouracil, forma contribuir informações significativas para solução desse problema e, se possível, tornar-se uma ferramenta terapêutica intestinal. Para tal, fêmeas camundongos da linhagem Balb/c...
Abstract: Peptidases play crucial roles in numerous physiological processes within living organisms. Therefore, they have been employed various pharmaceutical applications. Plant peptidases attracted considerable attention areas due to their specificity, stability across a diverse range of pH and temperatures, safety profile. Here, we focused on the use plant peptidases, mostly papain bromelain, produce biologically active peptides, which confer health advantages, including antioxidant,...
ABSTRACT Bacterial resistance represents one of the greatest challenges in modern medicine, requiring innovative strategies. This study presents rational design two synthetic analogue peptides, WK‐MAP1, and WG‐MAP2, inspired by structure enzyme papain (PDB 9PAP), emphasizing novelty using an as a model for developing new antimicrobials. Initially, silico studies, including molecular modeling docking experiments, revealed high affinity peptides mimetic bacterial membranes. Subsequently, vitro...
The latex of Calotropis procera has been used in the traditional medicinal system for treatment leprosy, ulcers, tumors, piles and diseases liver, spleen, abdomen toothache. It comprises a non-dialyzable protein fraction (LP) that exhibits anti-inflammatory properties dialyzable (DF) exhibiting pro-inflammatory properties. present study was carried out to evaluate effect LP sub-fractions on neutrophil functions nociception rodent models elucidate mediatory role nitric oxide (NO). subjected...