A5100652412- Plant biochemistry and biosynthesis
- Metabolism and Genetic Disorders
- Plant-Microbe Interactions and Immunity
- Biochemical Acid Research Studies
- Plant Molecular Biology Research
- Amino Acid Enzymes and Metabolism
- Plant Gene Expression Analysis
- Essential Oils and Antimicrobial Activity
- Cancer-related molecular mechanisms research
- Plant tissue culture and regeneration
- Phytochemicals and Antioxidant Activities
- Plant Stress Responses and Tolerance
- Immunotherapy and Immune Responses
- Cancer, Hypoxia, and Metabolism
- Photosynthetic Processes and Mechanisms
- Phytochemical compounds biological activities
- Fungal Biology and Applications
- Insect Pest Control Strategies
- Plant Virus Research Studies
- Colorectal Cancer Treatments and Studies
- Biochemical and biochemical processes
- Inflammasome and immune disorders
- Antioxidant Activity and Oxidative Stress
- Plant Growth Enhancement Techniques
- Plant nutrient uptake and metabolism
Hunan Agricultural University
2011-2025
University of Chinese Academy of Sciences
2025
Shanghai Jiao Tong University
2024
Toxicologie, Pharmacologie et Signalisation Cellulaire
2023
Cell Signaling Technology (United States)
2023
Weifang Medical University
2022
Fujian Agriculture and Forestry University
2019-2021
Ministry of Education of the People's Republic of China
2009-2010
Northwest University
2009
Modern horticultural crop production systems target the exploitation of sustainable techniques for improvement while maintaining balance with environment. Several beneficial microbes have been investigated and yielded remarkable results. The endophytic fungus, Piriformospora indica, is one microbe group potential to offer numerous benefits opportunities in modern production. This plant growth-promoting mycorrhizal fungus particular interest due its implications growth development. has...
The LOX genes have been identified and characterized in many plant species, but studies on the banana are very limited. In this study, we respectively 18 MaLOX, 11 MbLOX, 12 MiLOX from Musa acuminata, M. balbisiana itinerans genome data, investigated their gene structures physicochemical properties of encoded proteins. Banana LOXs showed a preference for using ending with G/C proteins can be classified into 9-LOX, Type I 13-LOX II subfamilies. expansion MaLOXs might result combined actions...
Abstract The fungus, Fusarium oxysporum f. sp. cubense ( Foc ), is the causal agent of wilt disease, which most serious disease affecting whole banana industry. Although extensive studies have characterized many -responsive genes in banana, molecular mechanisms on microRNA level underlying both defense and pathogenesis are not yet fully understood. In this study, we aimed to reveal role miRNA during banana- TR4 interactions. Illumina sequencing was used changes small RNAome profiles roots...
Many viruses alter the phospholipid metabolism to benefit their own life cycles. It is unclear whether host or virus driving reprogramming, and how infections are affected by metabolic status. Here we report that phospholipase A2 inhibitor LY6/PLAUR domain-containing protein (PINLYP) inhibits Kaposi’s sarcoma-associated herpesvirus (KSHV) lytic reactivation remodeling especially triacylglycerol (TAG) biosynthesis. PINLYP deficiency led increased cPLA2α activity, cPLA2α-mediated AKT...
Abstract The regulatory mechanism of flavonoids, which synergise anti‐malarial and anti‐cancer compounds in Artemisia annua , is still unclear. In this study, an anthocyanidin‐accumulating mutant callus was induced from A. comparative transcriptomic analysis wild‐type calli performed, based on the next‐generation Illumina/Solexa sequencing platform de novo assembly. A total 82,393 unigenes were obtained 34,764 annotated public database. Among these, 87 assigned to 14 structural genes...
Fatty acid synthase (FASN) acts as the central member in fatty synthesis and metabolism processes, which regulate oncogenic signals tumor immunogenicity. To date, no studies have reported connection of FASN mutations with ICI efficacy. In this study, from 631 melanoma 109 NSCLC patients who received treatments, we retrospectively curated multiomics profiles treatment data. We also explored potential molecular biological mechanisms behind alterations. patients, were observed to associate a...
Transformation of Artemisia annua, which produces the sesquiterpenoid endoperoxide artemisinin widely used for treatment malaria, has been hampered by low efficiency adventitious shoot and root formation on a selective medium containing additional compounds Agrobacterium decontamination. Here we identified several factors were all shown to be importance optimization annua transformation. Results indicated that stem internodes showed better resistance capacity decontaminator than leaves did....
Adventitious root (AR) formation is a critical process for plant clonal propagation. The role of secondary metabolites in AR still poorly understood. Chemical and physical mutagenesis combination with somatic variation were performed on Artemisia annua order to obtain mutant changes adventitious rooting composition metabolites. Metabolic morphological analyses the iar (increased rooting) coupled vitro assays used elucidate relationship between formation. only detected differences wild-type...
In order to discover the formation mechanism of carotenoid derived aroma, which has been wildly used on protection crop against insect attacks, full-length cDNA an Artemisia annua cleavage dioxygenase (AaCCD1) was cloned by rapid amplification ends. The function AaCCD1 characterized expression in a strain E. coli accumulating carotenoids and enzyme assay vitro. completed open read frame 1629 bp it encoded 542-amino acid protein with 77% amino identity Arabidopsis thaliana CCD1, predicted...
Abstract Fusarium wilt disease, caused by oxysporum f.sp. cubense ( Foc ), has been recognized as the most devastating disease to banana. The regulatory role of long non-coding RNAs (lncRNAs) in plant defense verified many species. However, understanding their during early TR4 tropical race 4) infection stage is very limited. In this study, lncRNA sequencing was used reveal banana root transcriptome profile changes stages. Quantitative real time PCR (qRT-PCR) performed confirm expression...
Ku70, a DNA repair protein, binds to the damaged ends and orchestrates recruitment of other proteins facilitate double-strand breaks. Besides its essential role in repair, several studies have highlighted non-classical functions Ku70 cellular processes. However, function immune homeostasis anti-tumor immunity remains unknown. Here, we discovered marked association between elevated expression unfavorable prognosis lung adenocarcinoma, focusing specifically on increased levels...
<div>Abstract<p><i>De novo</i> nucleotide biosynthesis is essential for maintaining cellular pools, the suppression of which leads to genome instability. The metabolic enzyme transketolase (TKT) in nonoxidative branch pentose phosphate pathway (PPP) regulates ribose 5-phosphate (R5P) levels and <i>de biosynthesis. TKT required cell proliferation human liver cancer lines, yet role injury initiation remains be elucidated. In this study, we generated a...
<p>Supplementary materials, methods and figures</p>
<p>Supplementary materials, methods and figures</p>
<div>Abstract<p><i>De novo</i> nucleotide biosynthesis is essential for maintaining cellular pools, the suppression of which leads to genome instability. The metabolic enzyme transketolase (TKT) in nonoxidative branch pentose phosphate pathway (PPP) regulates ribose 5-phosphate (R5P) levels and <i>de biosynthesis. TKT required cell proliferation human liver cancer lines, yet role injury initiation remains be elucidated. In this study, we generated a...