A5002836630- Dialysis and Renal Disease Management
- Gut microbiota and health
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Cancer survivorship and care
- Pharmacological Effects and Toxicity Studies
- Bipolar Disorder and Treatment
- Head and Neck Cancer Studies
- Health Systems, Economic Evaluations, Quality of Life
- Tryptophan and brain disorders
- Health Literacy and Information Accessibility
- Polyomavirus and related diseases
- Mobile Health and mHealth Applications
- Metabolomics and Mass Spectrometry Studies
- Pain Management and Opioid Use
- Social Media in Health Education
- Clostridium difficile and Clostridium perfringens research
- Restless Legs Syndrome Research
- Cancer-related cognitive impairment studies
- Diet and metabolism studies
- Blood Pressure and Hypertension Studies
- Blood donation and transfusion practices
- Cannabis and Cannabinoid Research
- Health and Wellbeing Research
- Renal and Vascular Pathologies
University of Illinois Chicago
2017-2025
D.Y. Patil University
2024
University of Illinois Urbana-Champaign
2021-2023
Intercept Pharmaceuticals (United States)
2021
University of Chicago
2021
GTx (United States)
2020-2021
National Institute of Diabetes and Digestive and Kidney Diseases
2019
Oregon Health & Science University
2013-2015
University of Chicago Medical Center
2013-2015
Washington University in St. Louis
2005-2006
Prophylaxis reduces cytomegalovirus (CMV) disease, but is associated with increased costs and risks for side effects, viral resistance late onset CMV disease. Preemptive therapy avoids drug requires frequent monitoring may not prevent complications of asymptomatic replication. Kidney transplant recipients at risk (D+/R-, D+/R+, D-/R+) were randomized to prophylaxis (valganciclovir 900 mg q.d. 100 days, n=49) or preemptive (900 b.i.d. 21 DNAemia (CMV DNA level>2000 copies/mL in >or=1 whole...
Chronic kidney disease (CKD) confers a high burden of uremic symptoms that may be underrecognized, underdiagnosed, and undertreated. Unpleasant symptoms, such as CKD-associated pruritus emotional/psychological distress, often occur within symptom clusters, treating 1 potentially alleviate other in cluster. The Living Well with Kidney Disease Effective Symptom Management Consensus Conference convened health experts leaders advocacy groups networks worldwide to discuss the effects unpleasant...
The C-X-C chemokine receptor type 4 (CXCR4)/stromal cell derived factor-1 (SDF-1 or CXCL12) interaction and the resulting signaling cascade play a key role in metastasis inflammation. On basis of previously published CXCR4 antagonist 5 (WZ811), series novel nonpeptidic anti-CXCR4 small molecules have been designed synthesized to improve potency. Following structure−activity profile around 5, more advanced compounds N,N′-(1, 4-phenylenebis(methylene)) dipyrimidin-2-amines were discovered...
To date, the clinical trials of tacrolimus (TAC) versus cyclosporine modified (CsA), have not defined which agent is more cost-effective for immunosuppression in renal transplant recipients especially a quadruple immunosuppressive regimen.The objective this randomized, prospective study was to compare and economic outcomes TAC CsA, regimen that consisted Thymoglobulin induction, an antimetabolite, prednisone. Between December 2000 October 2002, 200 patients were enrolled randomized 2:1...
Introduction: Diabetic kidney disease (DKD) increases morbidity and mortality in individuals with diabetes. This study aimed to examine the relationships between cardiometabolic factors, high-sensitivity C-reactive protein (hs-CRP), physical activity (PA) measured as total METs, risk of DKD adults. Additionally, it explored moderators association PA METs-DKD. Hypothesis: We hypothesized that lower levels factors hs-CRP, along higher METs are associated reduced also posited age race/ethnicity...
Nurse scientists play an important role in studying complex relationships among human genetics, environmental factors, and the microbiome, all of which can contribute to health disease. Therefore, it is essential that they have tools necessary execute a successful microbiome research study. The purpose this article highlight methodological factors for nurse consider when designing In addition considering influence host-associated microbiomes (i.e., microorganisms associated with organisms...
Background: Despite our knowledge of barriers to the early stages transplant process, we have limited insight into patient-reported prekidney medical evaluation in populations largely at-risk for failure. Methods: One-hundred consecutive adults were enrolled at an urban, Midwestern center. Demographic, clinical, and quality life data collected prior patients visit with a surgeon/nephrologist (evaluation begins). Patient-reported completion using Subjective Barriers Questionnaire 90-days...
Barriers to kidney transplant for African Americans are well documented in the literature. Little information on ownership of and communication technology use such populations has been published.To characterize racial differences related patients.A single-center, cross-sectional survey study.An urban Midwestern center.78 pretransplant patients 177 recipients.The consisted 6 demographic questions, 3 disease-related 9 technology-related questions. Dichotomous (yes/no) Likert-scale items were...
Abstract Background Patient access to health information using electronic patient portals is increasingly common. Portal use has the potential improve patients’ engagement with their and particularly important for patients chronic illness; however, abilities, attitudes, of are poorly understood. Methods A single-center, cross-sectional survey was conducted 240 consecutive pre- post-kidney transplant all levels technological proficiency who presented an urban center in United States. The...
Background Symptom burden associated with chronic kidney disease can be debilitating, a negative effect on patient health-related quality of life. Latent class clustering analysis is an innovative tool for classifying symptom experience. Objectives The aim the study was to identify subgroups patients at greatest risk high burden, which may facilitate development patient-centered management interventions. Methods In this cross-sectional analysis, baseline data were analyzed from 3,921 adults...
Extensive evidence exists that patients with head and neck cancer (HNC), including oral cancer, experience multiple local, systemic, psychological symptoms across the trajectory (Murphy et al., 2019; Muthu 2018; Speksnijder 2021; Townes 2020). Some of these can continue even after surgical resection a tumor (Crowder 2018) occur together as symptom clusters (SCs). SCs have been found to synergistic effects on patient outcomes (Oh 2019), signifying need for advanced SC research in cancer.
Context The Internet is a staple of electronic communication and essential to the emerging telemonitoring health information technology interventions for adults with chronic diseases. Objective To identify determinants frequent use in an urban kidney transplant population United States. Design A single center, cross-sectional survey study Setting An Midwestern center Participants 78 pretransplant 177 posttransplant patients Main Outcome Measures Frequent use, defined as using more than 5...