A5041002023- Lymphatic System and Diseases
- Diagnosis and Treatment of Venous Diseases
- Parasitic Diseases Research and Treatment
- Parasites and Host Interactions
- Esophageal and GI Pathology
- Systemic Sclerosis and Related Diseases
- Diabetic Foot Ulcer Assessment and Management
- Gastric Cancer Management and Outcomes
- Histone Deacetylase Inhibitors Research
- Esophageal Cancer Research and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Protein Degradation and Inhibitors
- Insect symbiosis and bacterial influences
- S100 Proteins and Annexins
- Cerebrovascular and genetic disorders
- Ubiquitin and proteasome pathways
- Infrared Thermography in Medicine
- Mosquito-borne diseases and control
- Body Contouring and Surgery
New York Institute of Technology
2022
Icahn School of Medicine at Mount Sinai
2021
Georgia Institute of Technology
2014-2020
Emory University
2020
ELL, P. J.; HOCKNELL, J. M.L.; JARRITT, H.; CULLU, M I.; LU, I D.; CAMPO-COST, A NOWOTNIK, D. P.; PICKETT, R. CANNING, L. R.; NEIRINCKX,
Significance Cullin-RING E3 ubiquitin ligases (CRLs) direct protein degradation to impact a myriad of physiological and pathological processes including cancer. This work reports the small-molecule compounds 33-11 KH-4-43 as inhibitors CRL4 with anticancer potential. These have provided an opportunity for developing tool address mechanistic phenotypic questions about in biochemical, cell-based, animal studies. The results correlation studies between cullin4 level compounds’ cytotoxic...
Abstract Background Lymphedema is a common complication of breast cancer treatment that affects one in five survivors, yet there no reliable method to detect lymphedema the subclinical range. The objective this study was determine feasibility and reliability using an infrared 3D scanning device (ISD) as peri-operative limb volume measurement tool. Methods Fifteen patients were analyzed based on inclusion criteria. Peri-operative measurements obtained tape measure ISD. Volumes calculated...
Background: There are various methods of detecting and monitoring arm lymphedema after breast cancer (BC) treatment. Using volumetric measurements is the most common method performed clinically in United States, several techniques exist. Recently, use infrared cameras has been explored by groups. This study shows this technology its ability to assess volume comparable Perometer while being more inexpensive, having a smaller footprint clinics, easy use. Methods Results: Seventy-three BC...
Lymphatic Filariasis, a Neglected Tropical Disease, is caused by thread-like parasitic worms, including B. malayi, which migrate to the human lymphatic system following transmission. The parasites reside in collecting vessels and lymph nodes for years, often resulting lymphedema, elephantiasis or hydrocele. mechanisms driving worm migration retention within lymphatics are currently unknown. We have developed an integrated vitro imaging platform capable of quantifying malayi behavior...
Abstract Lymphatic filariasis is a neglected tropical disease caused by roundworm parasites such as Brugia malayi that spread via mosquito vector. In vitro culture of these provides controlled conditions to understand parasite biology and cheaper way screen potential micro- macrofilaricides. Published studies have used wide array approaches metrics regarding in cultures B. ; result, drawing comparisons identifying the reasons why inability reproduce outcomes are difficult. This study sought...
Background: There are many techniques of monitoring leg lymphedema during physical therapy. Taking volumetric measurements with a tape measure is among the most common clinically, and changes in volume typically used to therapy efficacy. This study shows how Kinect infrared (IR) sensor custom algorithms can assess circumferences volumes comparable taken by trained therapist while exploring regional determine uniformity change. Methods Results: Leg were measured 38 patients using...
Introduction: Ménétrier disease (MD) is a rare protein-losing hypertrophic gastropathy usually confined to the gastric fundus and body. Involvement of esophageal inlet patch extremely rare. We report case symptomatic MD involving that was managed with endoscopic submucosal dissection (ESD). Case Description/Methods: A 27-year-old woman history referred our clinic for further evaluation dysphagia globus sensation. She had family adenocarcinoma in her maternal grandmother who passed away at...
Abstract Background Lymphedema is a common complication of breast cancer treatment that affects one in five survivors yet there no reliable method to detect lymphedema the subclinical range. The objective this study was determine feasibility and reliability using an infrared 3D scanning device (ISD) as peri-operative limb volume measurement tool.Methods Fifteen patients were analyzed based on inclusion criteria. Peri-operative measurements obtained tape measure ISD. Volumes calculated...
Abstract Background Lymphedema is a common complication of breast cancer treatment that affects one in five survivors yet there no reliable method to detect lymphedema the subclinical range. The objective this study was determine feasibility and reliability using an infrared 3D scanning device (ISD) as peri-operative limb volume measurement tool. Methods Fifteen patients were analyzed based on inclusion criteria. Peri-operative measurements obtained tape measure ISD. Volumes calculated...