- Cerebrospinal fluid and hydrocephalus
- Head and Neck Surgical Oncology
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
- Craniofacial Disorders and Treatments
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Cleft Lip and Palate Research
- Vascular Malformations Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Neurofibromatosis and Schwannoma Cases
- Child Abuse and Related Trauma
- Spinal Hematomas and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Spinal Fractures and Fixation Techniques
- Intracranial Aneurysms: Treatment and Complications
- Infectious Diseases and Tuberculosis
- Teratomas and Epidermoid Cysts
- Neonatal Respiratory Health Research
- Facial Trauma and Fracture Management
- Musculoskeletal pain and rehabilitation
- Bacterial Infections and Vaccines
- Prion Diseases and Protein Misfolding
Hospital Universitario Virgen de la Arrixaca
2008-2020
Universidad de Murcia
2005-2017
Boston Children's Hospital
2005-2012
Instituto de Neurologia Y Neurocirugia
2001-2011
Servicio Murciano de Salud
2003-2011
Centro Médico Sanitas Murcia
1999-2008
National Institute of Infectious Diseases
2000
National Health Service
1991-1997
Western General Hospital
1994
National Institute of Neurological Disorders and Stroke
1994
Abstract The objective of this article is to assess the safety intraspinal infusion autologous bone marrow mononuclear cells (BMNCs) and, ultimately, look for histopathological signs cellular neurotrophism in amyotrophic lateral sclerosis (ALS) patients. We conducted an open single arm phase I trial. After 6 months observation, BMNCs were infused into posterior spinal cord funiculus. Safety was primary endpoint and defined as absence serious transplant-related adverse events. In addition,...
We tested DNA from 15 centrally infected cases of iatrogenic Creutzfeldt-Jakob disease (CJD) (dura mater or corneal homografts and stereotactic EEG electrodes), 11 peripherally (native human growth hormone gonadotrophin), 110 control individuals for the presence mutations in chromosome 20 amyloid gene. No patient had any known pathogenic point insert found familial disease, but allelic homozygosity at polymorphic codon 129 was present all two (92%) 26 patients, compared with 54 (50%)...
Four patients who received dural grafts of cadaveric origin in the course posterior fossa procedures subsequently developed Creutzfeldt-Jakob disease (CJD). The interval from placement to clinical onset CJD ranged 16 months nine years. Initial presentation consisted cerebellar symptoms, with dementia and myoclonus developing later stages disease. EEGs showed diffuse slowing that evolved a periodic activity pattern. CT MRI were unremarkable early but pronounced cerebral atrophy widened sulci...
The occurrence of bilateral temporal arachnoid cysts has been considered as a rare event. Unilateral pouches have reported in few instances associated with neurofibromatosis. authors describe 5-year-old girl who presented obvious stigmata von Recklinghausen's disease. To the best our knowledge, this is first time that association described literature. (J Child Neurol 1993;8:383-385).
Object The aim of this study was to evaluate whether clinical improvement is noticeable after a minimally invasive procedure such as that used with the Aperius PercLID System in patients degenerative lumbar spinal stenosis (DLSS) and neurogenic intermittent claudication (NIC). Methods were treated aforementioned system at 3 different centers. initial requirement be included minimum follow-up 12 months. authors studied 40 cases DLSS NIC (age 72.7 ± 8.08 years). Symptom severity, physical...