A5103077022- Hepatitis C virus research
- HIV/AIDS drug development and treatment
- Public Health in Brazil
- Liver Disease and Transplantation
- Chronic Lymphocytic Leukemia Research
- Hepatitis B Virus Studies
- Hepatitis Viruses Studies and Epidemiology
- Systemic Lupus Erythematosus Research
- Liver Disease Diagnosis and Treatment
- Science and Education Research
- Peripheral Nerve Disorders
- Parvovirus B19 Infection Studies
- Monoclonal and Polyclonal Antibodies Research
- Nerve Injury and Rehabilitation
- Respiratory and Cough-Related Research
- Musculoskeletal Disorders and Rehabilitation
- Herbal Medicine Research Studies
- Global Health Workforce Issues
- HIV/AIDS oral health manifestations
- Palliative and Oncologic Care
- Complementary and Alternative Medicine Studies
Universidade Federal do Rio Grande do Sul
2013-2025
Hospital de Clínicas de Porto Alegre
2018
Several countries have used pegylation technology to improve the pharmacokinetic properties of essential drugs. Recently, a novel interferon alfa-2b protein conjugated four-branched 12 kDa polyethylene glycol molecules was developed jointly between Cuba and Brazil. The aim this study compare BIP48 (pegylated from Bio-Manguinhos/Fiocruz, Brazil) those PEGASYS® (commercially available pegylated alfa-2a Roche Pharmaceutical). This phase I, single-centre, randomized, double-blind crossover trial...
The common cold and other viral airway infections are highly prevalent in the population, their treatment often requires use of medications for symptomatic relief. Paracetamol is as an analgesic antipyretic; chlorphenamine antihistamine; phenylephrine, a vasoconstrictor decongestant. This randomized, double-blind, placebo-controlled trial sought to evaluate efficacy safety fixed-dose combination paracetamol, phenylephrine flu-like syndrome adults. study enrolled 146 individuals aged 18 60...
Abstract The prevalence of anti-hepatitis E virus (HEV) antibodies has a high heterogeneity worldwide. South American data are still scarce. aim this study was to evaluate the HEV in populations at risk comparison blood donors (BD). A cross-sectional carried out adults different including crack users (CK), residents low income area (LIA), cirrhotic (CIR) and liver transplant patients (LT) compared with BD. WANTAI ELISA test used real-time PCR (in-house for screening ALTONA as confirmatory...
Introduction and aim Comorbidities comedication are common in patients with hepatitis C, which could result a risk of drug-drug interaction. The objective this study was to evaluate the prevalence comorbidities, interactions involving direct-acting antivirals population. Methods comedications were evaluated retrospective cohort C patients. Drug-drug estimated real life simulated data on following drug regimens: telaprevir; elbasvir/grazoprevir, ombitasvir/paritaprevir/r/ritonavir (2D...
Introduction and aim. Despite the emergence of new treatments for genotype 3 HCV (G3 HCV), there is still a lack data about this particular subgroup in Brazil. We aimed to describe clinical sociodemographic variables treatment profile G3 Brazilian patients. Methods. This was descriptive, retrospective study, performed specialized center South Region. Medical charts patients diagnosed with were reviewed collect clinical, information. R esults. 564 subjects enrolled, mean age 59.3 years...
ribavirina, no tratamento de pacientes com
<h3>Background</h3> Lupus patient's expectations are no different than everyone else's: 'A better life'. But achieving it requires steps because entails (1) A prompt diagnosis, (2) Access to effective treatment with low side-effects, (3) Resolving fatigue, depression and the social impact of disease, (4) Being involved – individually collectively. <h3>Methods</h3> LUPUS EUROPE is umbrella organisation that federates, since more 30 years, national self-help lupus groups around Europe. Through...