A5061231024- Tuberculosis Research and Epidemiology
- Oral microbiology and periodontitis research
- Pneumonia and Respiratory Infections
- Salivary Gland Disorders and Functions
- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Diabetes Management and Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Neurological Disorders and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Advanced Glycation End Products research
- Infectious Diseases and Tuberculosis
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- HIV/AIDS drug development and treatment
- Pharmaceutical studies and practices
- Emergency and Acute Care Studies
- SARS-CoV-2 and COVID-19 Research
- Hemoglobinopathies and Related Disorders
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Lipoproteins and Cardiovascular Health
- Laser Applications in Dentistry and Medicine
- Antioxidant Activity and Oxidative Stress
- Diagnosis and treatment of tuberculosis
- Oral Health Pathology and Treatment
Babcock University
2021-2025
Adeleke University
2023
University College Hospital, Ibadan
2020-2022
University of Cape Town
2018-2021
Health First
2019
Afe Babalola University
2019
University of Ibadan
2012-2017
Optimal treatment regimens for patients with extensively drug-resistant tuberculosis (XDR-TB) remain unclear. Long-term prospective outcome data comparing XDR-TB and without bedaquiline from an endemic setting are lacking. We prospectively followed-up 272 South African (49.3% HIV-infected; median CD4 count 169 cells·µL −1 ) newly diagnosed between 2008 2017. Outcomes were compared those who had not received (pre-2013; n=204) (post-2013; n=68; 80.9% linezolid in addition). The 24-month...
ABSTRACT Global health has been thrown into turmoil by the COVID-19 pandemic, which caused devastating morbidity and unprecedented loss of life in almost all continents world. It was predicted that magnitude pandemic Africa will be high because poor structure intensely living condition, but not happened, surprisingly. hypothesized youthful population a vastly primed immune system were protective, many people may have exposed without coming down with severe disease. Most them would presented...
There are limited data on combining delamanid and bedaquiline in drug-resistant tuberculosis (DR-TB) regimens. Prospective long-term outcome data, including HIV-infected persons, unavailable. We prospectively followed up 122 South African patients (52.5% HIV-infected) with DR-TB poor prognostic features between 2014 2018. examined outcomes safety those who received a bedaquiline-based regimen (n=82) compared to bedaquiline–delamanid combination (n=40). was no significant difference 6-month...
Treatment outcomes of patients with extensively drug-resistant tuberculosis (XDR-TB) are suboptimal and treatment options remain limited. Linezolid is associated improved but also substantial toxicity, details about the relationship between these lacking from resource-poor HIV-endemic settings.This was a prospective follow-up study 63 South African XDR-TB (58.7% HIV-infected; median CD4 131 cells/μl) 2014 2018. The frequency severity linezolid-associated adverse events impact on were...
BACKGROUND: There are no data comparing the 6-9 month oral three-drug Nix regimen (bedaquiline, pretomanid and linezolid [BPaL]) to conventional regimens containing bedaquiline (B, BDQ) (L, LZD).METHODS: Six-month post end-of-treatment outcomes were compared between Nix-TB (n = 109) 102 prospectively recruited extensively drug-resistant TB patients who received an ˜18-month BDQ-based (median of 8 drugs). A subset BDQ LZD 86), a subgroup these 75) served as individually matched controls in...
Tuberculosis (TB) is arguably one of the oldest diseases known to mankind. Cases have been reported in virtually all countries world, and age groups are suffer from disease. TB among highest infectious disease causes death globally, rate not abating despite efforts aimed at eradicating pathogen. Several drug combinations used treat patients infected with TB, some new drugs currently being developed. The pathogen has, however, continued sustain its infectivity prevalence humans. Innovative...
AIM:To determine the levels of salivary immunoglobulin classes in Nigerian smokers and non-smokers with periodontitis.METHODS: Sixty-nine individuals were recruited into this study after obtaining informed consent.They subdivided three groups that consisted 20 (aged 46 ± 11 years) cigarette periodontitis (S+P); 24 (40 12 without (S-P); 25 (53 (NS+P).An oral maxillofacial surgeon used radiographs for periodontal probing diagnosis periodontitis.The included subjects who smoked at least six...
The onset of menstruation denotes a landmark event in the pubertal development adolescent girl. Adolescent girls should have adequate knowledge menstrual hygiene before menarche. Lack and good practices can far-reaching consequences for girl's well-being, dignity, reproductive health, sexual health. Hygiene-related during are considerable importance. This study assessed Practice among Ede South local government secondary schools, Ede, Osun State. adopted descriptive cross-sectional design....
Regular monitoring of glycaemic levels in patients with diabetes mellitus forms a major fulcrum for ensuring desirable treatment outcome and good quality life affected individuals. Glycated haemoglobin (HbA1c) measurement is common dependableoption determining long-term control. Unfortunately, it relatively expensive not readily available most low- ncome settings. Measuring fasting plasma glucose (FPG) the cheaper alternative if correlates HbA1c. A retrospective study into clinical records...
<sec> <title>BACKGROUND</title> Diabetes mellitus is associated with increased prevalence of oral diseases. Reactive oxygen species have been implicated in the development these The saliva contains a balanced proportion protective antioxidants and reactive species, disrupting this balance favours disease development. However, level salivary markers oxidative stress has not sufficiently studied diabetics. </sec> <title>OBJECTIVE</title> Thus, study aimed to measure H2O2, NO MDA diabetic...
Objective: Diabetes mellitus is associated with increased prevalence of oral diseases for which reactive oxygen species have been implicated. The saliva contains protective antioxidants statutorily curtail these destructive molecules. A functional compromise the may precipitate oxidative stress leading to disease susceptibility. However, salivary markers not sufficiently studied in diabetics. Methods: total 166 adults were recruited this study. They comprised 95 Type 2 diabetic patients and...
Objective: Increasing evidence has shown that ApoE polymorphism is associated with the early onset of cardiovascular and neurological diseases in patients on HAART. The frequency occurrence alleles genotypes vary by race population. study describes pattern seen among adults Ibadan, Nigeria. Methods: This cross-sectional was conducted 124 randomly selected HIV-infected persons protease inhibitor therapy who receive care at adult antiretroviral clinic University College Hospital (UCH), Ibadan....
Background: Laboratory test request forms usually accompany patient’s samples to the laboratory, providing biodata and clinical details of patient. This information is for purposes identification guiding pathologists accurately interpret result. Clinicians however do not provide all required information, thus making interpretation difficult. The frequency such incompleteness assessed in this study.Methods: received at Chemical Pathology laboratory between July September 2020 were...
Objective: Diabetes mellitus is associated with increased prevalence of oral diseases for which reactive oxygen species have been implicated. The saliva contains protective antioxidants statutorily curtail these destructive molecules. A functional compromise the may precipitate oxidative stress leading to disease susceptibility. However, salivary markers not sufficiently studied in diabetics. Methods: total 166 adults were recruited this study. They comprised 95 Type 2 diabetic patients and...
<b>Background:</b> The global health was thrown into a turmoil by the SARS-CoV-2 causing devastating morbidity and unprecedented loss of life in almost all continents world. It predicted that magnitude pandemic Africa will be high due to poor structure intensely living condition, but has not happened, surprisingly. hypothesized youthful population vastly primed immune system were protective, many people may have been exposed without coming down with severe disease. Most them would presented...