A5103275189- Historical and Archaeological Studies
- Ancient and Medieval Archaeology Studies
- Medieval European History and Architecture
- Historical and Cultural Studies of Poland
- BRCA gene mutations in cancer
- Polish Historical and Cultural Studies
- DNA Repair Mechanisms
- Prostate Cancer Treatment and Research
- Linguistics and language evolution
- Language and Culture
- Genetic factors in colorectal cancer
- Polish socio-economic development
- Ancient Mediterranean Archaeology and History
- Economic and Fiscal Studies
- Archaeology and ancient environmental studies
- Image Processing and 3D Reconstruction
- Management and Organizational Practices
- Renal cell carcinoma treatment
- Berry genetics and cultivation research
- Globalization, Economics, and Policies
- Parasite Biology and Host Interactions
- Renewable energy and sustainable power systems
- PARP inhibition in cancer therapy
- Parasitic Diseases Research and Treatment
- Urban Development and Cultural Heritage
Pomeranian Medical University
2007-2024
Adam Mickiewicz University in Poznań
2010-2023
Instytut Archeologii i Etnologii
2020
University of Fine Arts in Poznań
2018
National Veterinary Research Institute
2014
University of Łódź
2006-2010
Szczecin Academy of Arts
2004
Variants in the CHEK2 have been found to be associated with prostate cancer risk United States and Finland. We sequenced gene 140 Polish patients then genotyped three detected variants a larger series of cases controls. truncating mutations (IVS2 + 1G>A or 1100delC) were identified 9 1921 controls (0.5%) 11 690 (1.6%) unselected [odds ratio (OR) = 3.4; P 0.004]. These 4 98 familial (OR 9.0; 0.0002). The missense variant I157T was also more frequent men (7.8%) than (4.8%), but relative modest...
To evaluate whether an inactivating mutation in the gene for Nijmegen breakage syndrome (NBS1) plays a role etiology of prostate cancer, we compared prevalence 657del5 NBS1 founder allele 56 patients with familial 305 nonfamilial and 1500 control subjects from Poland. Loss heterozygosity analysis also was performed on DNA samples isolated 17 microdissected cancers, including 8 carriers mutation. The present 5 (9%) cancer (odds ratio, 16; P < 0.0001), 7 (2.2%) 3.9; = 0.01), 9 (0.6%)....
Abstract Several genome-wide searches for common cancers have lead to the identification of a small number loci that harbor low-risk cancer susceptibility markers. One marker, rs6983267 on chromosome 8q24, has been linked both colon and prostate cancer, is therefore good candidate multicancer marker. To determine range sites associated with rs6983267, we genotyped 7,665 cases representing 11 sites, 1,910 controls. A significant odds ratio (OR) was observed carriers genotype GG [OR, 1.77; 95%...
Abstract BACKGROUND The G84E mutation in the HOXB13 gene has been associated with a high lifetime risk of prostate cancer North America (about 20‐fold). geographical and ethnic extent this recurrent allele not yet determined. METHODS We assayed for presence 3,515 patients 2,604 controls from Poland estimated odds ratio allele. RESULTS was detected 3 (0.1%) individuals general population 20 (0.6%) men (Odds [OR] = 5.0; 95% CI: 1.5–16.7; P 0.008). present 4 416 (1.0%) familial (OR 8.4,...
Evidence to date that BRCA1 mutation carriers are at an increased risk of prostate cancer is mixed – both positive and negative studies have been published. To establish whether or not inherited variation in influences we genotyped 1793 men with Poland 4570 controls for three founder mutations (C61G, 4153delA 5382insC). A was present 0.45% the cases 0.48% (odds ratio=0.9; P=1.0). The odds ratios varied substantially by mutation. 5382insC most common mutations. It detected only one case...
Prostate cancer is the most common diagnosed in men and second leading cause of death male patients. The WHO suggests that cobalt involved carcinogenesis prostate cancer. There are, however, no studies associating levels patient survival. In this study, 261 Polish (n = 261) patients were recruited into a prospective cohort between 2009 2015. Serum measured using ICP-MS after diagnosis before treatment. All study participants assigned quartiles (QI-QIV) based on distribution serum among...
We investigated whether or not inherited variation in MSR1, RNASEL and E-cadherin contribute to prostate cancer risk Poland.We sequenced the coding region of these three genes individuals from Poland identified five common DNA variants (R462Q D541E RNASEL, R293X P275A 2076C>T (A692A) E-cadherin). These -160C>A promoter change were genotyped 737 cases 511 controls.The frequencies controls similar. did see any association for studied when stratified by age diagnosis, family history,...
In 2011-2013 1588 samples of dogs' blood were examined for dirofilariosis using Knott method, as well the Kingston and Morton method. The species microfilariae was determined on basis morphometric characteristics. Samples also Canine Heartworm Antigen Test. Positive a multiplex PCR assay confirmation. Microfilariae belonging to D. repens found in dogs from all provinces Poland. mean prevalence this observed Poland 11.7%. range intensity infection counted number 60 microl amounted between 1...
To evaluate the survival of patients with rare malignant histological subtypes renal cancer.The Heidelberg classification cell carcinoma (RCC) divides tumours into clear (CCC), papillary cancer (PC), chromophobic (ChC) and collecting duct (CDC). Sarcomatoid are in a different subgroup treated as final stage progression. Between 1990 1997, 319 nephrectomies were undertaken because RCC 317 patients. In 42 (13%) pathological findings showed other than CCC; 13 PC was confirmed histologically,...
Zwrócono uwagę na dążenie do wykorzystywania systemów wczesnego ostrzegania i rozpoznania jako jednego z narzędzi służących budowy przewagi konkurencyjnej. Podjęto próbę odpowiedzi pytania: czy jest to możliwe, jakie argumenty przemawiają za słusznością takiej tezy? Przedstawiono etapy systemu informacyjnego oraz przykładowe wskaźniki przydatne w konstruowaniu ostrzegania.
The article discusses a corded decoration on pottery from the Amphorae Globular Culture seasonal camp. Analysis of impressions pot outer surfaces revealed that this characteristic motif was produced by simple textile template. Fragments five-stranded cord (S/3S/2Z) - certainly not two-stranded one were sewn net 'band' (item sprang type). This technique guaranteed precise layout and space between particular (ca. 2 mm each) soft amphorae (?) surface irrespective an angle ornament placements...
The article’s objective is to present the first graphite goods found at princely part of Poznań stronghold. Pottery fragments, a disc with hole made sherd, and spindle whorl have been discovered foundations Mieszko I palatium, next remains goldsmith’s workshop. Relatively straightforward stratigraphy, despite later destruction caused by numerous construction phases Sacred Mary Church, along accompanied artifacts from layers, make possible date these finds period stretching 10 -1 1th 12th...
Abstract The article describes an attempt to identify the raw material of organic layers - mats identified within roofs and floors graves in Yampil Barrow Cemetery Complex. use gas chromatography infrared spectroscopy combined with microscopic analysis extracted “mat” sections significantly supplements our knowledge field weaving studied communities.