A5031809224- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Rheumatoid Arthritis Research and Therapies
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Lipid metabolism and disorders
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Microscopic Colitis
- Esophageal and GI Pathology
- Health Systems, Economic Evaluations, Quality of Life
- Foreign Body Medical Cases
- Biliary and Gastrointestinal Fistulas
- Intestinal and Peritoneal Adhesions
- Gastroesophageal reflux and treatments
- Spondyloarthritis Studies and Treatments
- Hepatitis Viruses Studies and Epidemiology
- Eosinophilic Esophagitis
- Healthcare Systems and Reforms
- Helicobacter pylori-related gastroenterology studies
- Cell death mechanisms and regulation
- Ocular Diseases and Behçet’s Syndrome
- Clostridium difficile and Clostridium perfringens research
- Restraint-Related Deaths
UConn Health
2023
Massachusetts General Hospital
2017-2022
Harvard University
2018-2022
Hacettepe University
2000-2020
KTO Karatay University
2018-2019
STATinMED (United States)
2018
Konya Numune Hastanesi
2018
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2009-2016
Ankara Numune Eğitim ve Araştırma Hastanesi
2014-2015
University of Duisburg-Essen
2013
Background This study compared diagnostic methods for identifying Blastocystis in stool samples, and evaluated the frequency of detection patients with irritable bowel syndrome (IBS) inflammatory disease (IBD). Results Discussion From a set 105 specimens submitted routine parasitological analysis, 30 were identified as positive by culture method. that group positives, Lugol's stain, trichrome staining, an immunofluorescence assay 11, 15, 26 samples respectively. Using standard, sensitivity...
Introduction: Many noninvasive tests have been studied for the diagnosis and determining liver fibrosis score (LFS).In this study, we aimed to research correlation of mean platelet volume (MPV) stage in patients with chronic hepatitis B (CHB).Patients Methods: Fifty-nine CHB were enrolled retrospectively into study.Age-sex matched 25 healthy subjects used as control group.The following data obtained from computerized patient registry database: HBV-DNA level, e-antigen seropositivity, enzymes...
Fetuin-A is a pro-inflammatory protein expressed by hepatocytes. Its course in morbidly obese patients with NAFLD (non-alcoholic fatty liver disease) following weight loss BAS (bariatric surgery) has not been fully elucidated yet. In the present study, we prospectively examined effects of on various metabolic factors at 4 weeks and 6 months after surgery. Blood tissues were retrieved from 108 before/during BAS, 50 these individuals met criteria for NASH steatohepatitis). expression was...
Summary Background Results are conflicting with respect to the renal effects of anti‐viral agents used for hepatitis B virus infection. Aim To compare short and long‐term in real‐life settings determine risk factors impairment during treatment. Methods 2221 treatment‐naïve patients were enrolled. Among these, 895 (302 lamivudine, 27 telbivudine, 282 entecavir, 273 tenofovir 11 adefovir initiated patients) had ‘repeated measures’ creatinine (baseline, 1st, 6th, 12th 24th month treatment)....
Coinfection with human immunodeficiency virus (HIV) accelerates hepatitis C (HCV)-related liver fibrosis. Macrophages are triggered during both viral infections and critical in inflammation/fibrogenesis. Liver fibrosis strongly associates serum soluble CD163 (sCD163, a macrophage activation marker); comprehensive evaluation HIV/HCV coinfection is lacking.
Summary Background Dyslipidaemia is frequent in non‐alcoholic steatohepatitis ( NASH ); however, it unclear if improvement liver histology associated with favourable changes cardiovascular disease CVD ) risk. Aims To evaluate the relationship of resolution and lipoprotein subfraction levels, markers endothelial dysfunction, macrophage activation. Methods One hundred seventeen individuals who participated Pioglitazone vs Vitamin E Placebo for Treatment Nondiabetic Patients PIVENS trial paired...
Parenteral transmission is the major route of hepatitis C virus in adults; however, vertical most common children. There are several factors that have been shown to be associated with virus, including RNA, human immunodeficiency coinfection, and peripheral blood mononuclear cell infection. As there no effective vaccine prevent infection, data describing safety new direct acting antiviral agents pregnancy, only preventive strategy for treat infection before becoming pregnant. Direct...
Crimean-Congo hemorrhagic fever (CCHF) is a viral tick-borne zoonosis, which severe illness, causing hemorrhages in humans. Mean platelet volume (MPV) used as surrogate marker of function and has been shown to be sign inflammation. The objective the present study examine association between MPV CCHF. We also aimed investigate coagulopathy markers mortality rates prognosis patients with CCHF.Ninety-three CCHF were enrolled retrospectively into 15 them excluded according exclusion criteria....
<b><i>Background/Aims:</i></b> Hepatocellular carcinoma (HCC) is the sixth most common malignancy worldwide and therapeutic options are scarce. As they might represent future targets for cancer therapy, expression of apoptosis-related genes in HCC particular interest. In this pilot study, we further examined human also focused on vitamin D signaling as be a regulator cell apoptosis. <b><i>Methods:</i></b> We employed tumor tissue serum samples...
<b><i>Background/Aims:</i></b> An unsuccessful colonoscopy procedure is often related to<b> </b>inadequate bowel cleansing. It difficult for patients to finish the whole 4 liters of polyethylene glycol-electrolyte lavage (PEG-EL) because its salty taste and large quantity. Pineapple juice has been shown be an effective agent in dissolution undigested food stomach. This study assessed effectiveness both 2 PEG-EL precolonoscopic cleansing quality...
Pantoprazole is a proton pump inhibitor that commonly used in the treatment of peptic ulcer disease (PUD) and metabolized by cytochrome P450 (CYP) enzymes CYP2C19 CYP3A4. substrate for multi-drug resistance protein 1 (MDR1). Single nucleotide polymorphisms (SNPs) CYP2C19, CYP3A4 MDR1 affect enzyme activity or gene expression proteins may alter plasma pantoprazole concentrations success PUD. In this study, we aimed to investigate association between genetic pharmacokinetics therapeutic...
Besides some genetic explanations of the native course ulcerative colitis (UC), most attributable factors are pathogenic bacterial agents. There conflicting data about relationship between Helicobacter pylori and rate UC in literature. Therefore, we aimed to investigate H. patients. Materials methods: Forty-nine individuals diagnosed with who had undergone upper gastrointestinal tract endoscopy for different reasons were included study. The presence stomach was checked by histopathological...
Cefuroxime is a second-generation cephalosporin antibiotic. It effective against susceptible bacteria causing infections of the middle ear, tonsillitis, throat infections, laryngitis, bronchitis, and pneumonia. also used in treating urinary tract skin gonorrhea. generally well tolerated Common adverse effects cefuroxime axetil are diarrhea, nausea, vomiting, headaches/migraines, dizziness abdominal pain.1 In literature, only two cases were reported that associated cholesthatic hepatitis...
Abstract Background : Alpha 1 antitrypsin (AT) deficiency is a hereditary disorder leading to the defective defence system against neutrophil elastasis in lung and accumulation of insoluble heterodimer AT molecules hepatocytes. Knowledge prevalence each country important organize public health policy. The aim this study determine Turkish population define cutoff value level serum detect heterozygous deficient subjects. Materials Methods Serum samples from 1,203 healthy blood donors were...
A 26-year-old man presented at our emergency department with a history of severe pelvic pain and bloating. The patient reported that he had inserted large light bulb in his rectum about 3 hours prior to presentation. On digital rectal examination, foreign body an irregular surface was palpated. An X-ray image the region revealed ([Fig. 1]). Attempted manual removal using suprapubic pressure failed. Colonoscopy completely obstructing lumen 2]). polypectomy snare failed remove it because...
Objective: We aimed to determine the risk factors of methicillin-resistant Staphylococcus aureus (MRSA) colonization, and impact colonization on MRSA infection evaluate necessity survey program in intensive care units (ICUs) Turkey.Methods: The patients hospitalized medical neurosurgical ICUs longer than 24 hr were included into study.To anterior nares swabs taken from each patient first 48 hr, followed by once a week till discharge ICUs.Results: During one-year follow-up period, number who...
Liver biopsy is an invasive procedure that currently still necessary for predicting underlying hepatic injury related to chronic viral hepatitis B (CVHB). To date, none of the studied non-invasive methods have been able replace liver biopsy. An apoptotic serum marker, M30, which has reported indicate ongoing fibrosis, popular in recent years.We aimed investigate possible role M30 CVHB-associated and its severity.Forty-eight patients undergoing evaluation severity CVHB-related 40 healthy...