A5071259300- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Intraocular Surgery and Lenses
- Cerebral Venous Sinus Thrombosis
- Vasculitis and related conditions
- Optical Coherence Tomography Applications
- Retinal Development and Disorders
- Acute Ischemic Stroke Management
- Pituitary Gland Disorders and Treatments
- Blood Pressure and Hypertension Studies
- Mosquito-borne diseases and control
- melanin and skin pigmentation
- Renal Diseases and Glomerulopathies
- Hormonal Regulation and Hypertension
- Vascular Malformations Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- RNA regulation and disease
- Autoimmune and Inflammatory Disorders
- Neurosurgical Procedures and Complications
Fondation Ophtalmologique Adolphe de Rothschild
2015-2025
Sorbonne Université
2019-2024
Pitié-Salpêtrière Hospital
2019-2024
Fondation de Rothschild
2021-2024
Centre hospitalier national d'ophtalmologie des Quinze-Vingts
2014-2024
Science Club
2024
Weatherford College
2024
Inserm
2024
Hôpital Lariboisière
2014-2023
Assistance Publique – Hôpitaux de Paris
2013-2023
To analyze the foveal microvasculature in eyes with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) and fluorescein (FA).In this retrospective study of 20 14 patients DR imaged OCTA FA, clinical features such as microaneurysms, capillary nonperfusion areas, intraretinal microvascular abnormalities were analyzed.In superficial plexus, a rarefaction capillaries areas was present all eyes. Some these nonperfused not detected on FA better delimited OCTA....
To describe the macular deep capillary plexus (DCP) in normal eyes using optical coherence tomography angiography.Retrospective study including 41 consecutive imaged angiography (RTVue XR Avanti; Optovue Inc). Default autosegmentation of superficial (SCP) and DCP, manual adjustments "deep settings" were used to analyze organization microvascularization investigate vivo connection between these networks.Mean age was 31 years (range, 22-55 years). The SCP DCP had 2 different organizations, but...
To assess the rate of choroidal neovascularization (CNV) detected by optical coherence tomography angiography (OCTA) in flat irregular pigment epithelium detachment (PED) chronic central serous chorioretinopathy.Data on all consecutive patients with chorioretinopathy who underwent OCTA over a 1-year period were reviewed. The presence PED, which was defined as an elevation retinal allowing visualization distinct Bruch's membrane assessed high-resolution OCT B-scan. Clinical, multimodal...
<h3>Importance</h3> Capillary dropout is a hallmark of diabetic retinopathy, but its role in visual loss remains unclear. <h3>Objective</h3> To examine how macular vessel density correlated with acuity (VA) patients younger than 40 years who have type 1 diabetes without edema retinopathy requiring panretinal photocoagulation. <h3>Design, Settings, and Participants</h3> Retrospective cohort study VA optical coherence tomography angiography data collected from consecutive during single visit...
To provide values of retinal vessel density (VD) in the three capillary plexuses, foveal avascular zone (FAZ) area, and layer thickness a cohort healthy subjects.The optical coherence tomography angiography maps 148 eyes 84 subjects, aged 22 to 76 years, were analyzed for measuring VD using Optovue device comprising projection artifact removal algorithm. Foveal metrics measured, relationship between findings age, sex, image quality was studied.The deep plexus showed lowest (31.6% ± 4.4%) all...
To study the relationship between location of cystoid spaces and retinal capillary nonperfusion areas in diabetic macular edema (DCME).In this retrospective study, 24 eyes 21 patients with chronic DCME were followed using optical coherence tomography angiography. The density superficial plexus deep was measured AngioAnalytics software all 20 healthy controls. Diabetic improved spontaneously or after treatment 11 eyes.The intraretinal surrounded by capillary-flow void 71% cases 96% cases. had...
To compare the changes in retinal perfusion on ultra-wide-field fluorescein angiography with diabetic retinopathy lesions observed fundus color photographs after 3 monthly anti-vascular endothelial growth factor injections.Retrospective interventional cohort study analyzing files of 14 patients DR (18 eyes). UWF photos and FA were analyzed at baseline (M0) 1 month third anti-VEGF injection (M3). The main outcomes included count number red dots (microaneurysms, hemorrhages) assessment...
Abstract Optical coherence tomography angiography is evolving towards wider fields of view. As single widefield acquisitions have a lower resolution, preventing an accurate segmentation vascular plexuses in the periphery, we examined retinal vascularisation from macula to periphery all quadrants, using 3 × 3-mm volume scans, obtain montages with sufficient image resolution up 11 mm foveal centre. Images were qualitatively and quantitatively analysed, C- B-scan approaches calculate capillary...
Acute macular neuroretinopathy (AMN) is an increasingly diagnosed disorder associated with several diseases. The aim of this study was to report the incidence AMN cases during 2020 coronavirus disease 2019 (COVID-19) pandemic year in a French hospital, and describe their different forms.All patients between 2020, Paris Rothschild Foundation Hospital, AMN, paracentral acute middle maculopathy (PAMM) multiple evanescent white dot syndrome (MEWDS) were retrospectively collected using software...
Purpose.: To assess the thickness of ganglion cell-inner plexiform layer (GCIPL) in eyes with resolved diabetic macular edema (DME), using spectral-domain optical coherence tomography (SD-OCT), and its relationship visual function.
Abstract This study tested if a high-resolution, multi-modal, multi-scale retinal imaging instrument can provide novel information about structural abnormalities in vivo. The examined 11 patients with very mild to moderate non-proliferative diabetic retinopathy (NPDR) and 10 healthy subjects using fundus photography, optical coherence tomography (OCT), OCT angiography (OCTA), adaptive optics scanning laser ophthalmoscopy (AO-SLO), OCTA (AO-OCT(A)). Of 21 eyes of patients, had NPDR, 8 2 1 no...
To compare the long-term outcomes of vitreomacular surgery in eyes with nontractional diabetic macular edema (DME) those from tractional DME.Retrospective comparative study 55 consecutive patients (73 eyes). Twenty were operated on for DME and 53 unresponsive to laser photocoagulation or triamcinolone intravitreal injections. The best-corrected visual acuity, central thickness, surgical complications analyzed.The mean follow-up duration was 5.3 ± 2.4 years group traction 4.4 1.7 without (P =...
To examine retinal vascular changes in the peripapillary and macular areas patients with pituitary adenoma (PA) using optical coherence tomography angiography (OCTA).Cross-sectional, retrospective study of 17 consecutive PA 16 healthy subjects. All underwent a neuro-ophthalmological examination to assess presence optic neuropathy (ON). Static automated perimetry (SAP), disc structural OCT [retinal nerve fibre layer (RNFL) ganglion cell complex (GCC) thicknesses] OCTA were performed....
Abstract Background Widespread use of retinal optical coherence tomography angiography (OCT-A) imaging in population-based studies requires methodological and analytical consensus to ensure reproducible accurate results. Objective Development a framework for assessment OCT-A image quality working with OCT-A-derived variables population studies. Methods Criteria were developed fovea-centered, 3x3-mm images acquired three commercially available devices. Inter- intragrader agreements overall...
Purpose To assess the long term anatomic and functional outcomes in giant retinal tear associated detachment identify factors with recurrence. Methods This is a retrospective monocentric study, of patients treated for GRT-RD between 2017 2022 at Rothschild Foundation Hospital, Paris, France. Results A total 65 eyes from 64 were analyzed mean follow up 21.5 months. Mean age was 52.7 years 89.2% them men. 69.3 % phakic, axial length 25.4 mm 15 had high myopia. size 147.7 degrees. Macula...
BACKGROUND AND OBJECTIVE: To compare capillary density (CD) changes assessed by optical coherence tomography angiography (OCTA) during diabetic retinopathy (DR) progression using three previously published methods: binarization, skeletonization, and automated flow (AFD). PATIENTS METHODS: Retrospective study of 98 eyes 74 patients with diabetes 18 control imaged OCTA. The macular CD at each stage DR was the methods were compared to eyes. RESULTS: AFD only method that detected differences...
Background: During the last decade, our understanding of cerebrospinal fluid (CSF) physiology has dramatically improved, thanks to discoveries both glymphatic system and lymphatic vessels lining dura mater in human brains. Evidence Acquisition: We detail recent basic science findings field CSF connect them with current pathophysiology idiopathic intracranial hypertension (IIH). Results: Transverse sinus (TS) stenoses seem play a major causative role symptoms IIH, as result decrease pressure...
Modeling techniques are an essential complement to clinical studies of the retina, as they provide access non-measurable parameters throughout network and enable simulation controlled disturbances or pathologies. In this work, we propose development a patient-specific one-dimensional model arterial circulation in retina. Our is based on conservation laws utilizes morphometric velocimetric data obtained through multimodal imaging construct topology impose realistic boundary conditions....
To report on the medical management of meningioma with compression optic chiasm associated use cyproterone acetate (CA).A 65-year-old woman who was being treated CA presented a recent decrease in visual function, leading to discovery giant olfactory groove chiasm. discontinued immediately, and her function improved dramatically. At 13 months, addition significant improvement neurocognitive symptoms, tumor volume reduced by 50%.In meningiomas CA, treatment cessation may result prompt symptoms...