- Neuropeptides and Animal Physiology
- Neurogenesis and neuroplasticity mechanisms
- Silkworms and Sericulture Research
- Epigenetics and DNA Methylation
- Sperm and Testicular Function
- Tryptophan and brain disorders
- Barrier Structure and Function Studies
- Animal and Plant Science Education
- Anesthesia and Neurotoxicity Research
- Cancer-related gene regulation
- Lipid Membrane Structure and Behavior
- S100 Proteins and Annexins
- Neuroinflammation and Neurodegeneration Mechanisms
- Receptor Mechanisms and Signaling
- Histone Deacetylase Inhibitors Research
- Insect Utilization and Effects
- Ferroptosis and cancer prognosis
- Sphingolipid Metabolism and Signaling
- Circadian rhythm and melatonin
- Neuroendocrine regulation and behavior
- Multiple Sclerosis Research Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Quantum Dots Synthesis And Properties
- Animal Genetics and Reproduction
- Chemical Reactions and Isotopes
University of Milan
2024-2025
University of Verona
2015-2017
University of Bologna
2006
Clinical and experimental studies indicate that muscarinic acetylcholine receptors are potential pharmacological targets for the treatment of neurological diseases. Although these have been described in human, bovine rat cerebral microvascular tissue, a subtype functional characterization mouse brain endothelium is lacking. Here, we show all (M1-M5) expressed endothelial cells. The mRNA expression M2, M3, M5 correlates with their respective protein abundance, but mismatch exists M1 M4 versus...
Abstract Recent findings indicate that fingolimod, the first oral drug approved for treatment of multiple sclerosis ( MS ), acts as a direct inhibitor histone deacetylases HDAC s) and enhances production brain‐derived neurotrophic factor BDNF ) in CNS . Both mechanisms are relevant to pathophysiology major depression. We examined antidepressant activity fingolimod mice subjected chronic unpredictable stress CUS model reactive depression endowed with face pharmacological validity. Chronic (3...
Native breed conservation is an important component of poultry biodiversity. The aim this work to describe different steps that lead donor selection for the implementation Italian Semen Cryobank Autochthonous Chicken and Turkey Breeds. variability within between breeds was evaluated, stored semen reproductive capacity in vivo tested using artificial insemination. from Bionda Piemontese, Bianca di Saluzzo Pepoi roosters collected processed. Concentration, volume, sperm membrane integrity,...
Qtracker(®)800 Vascular labels (Qtracker(®)800) are promising biomedical tools for high-resolution vasculature imaging; their effects on mouse and human endothelia, however, still unknown.Qtracker(®)800 were injected in Balb/c mice, brain endothelium uptake was investigated by transmission electron microscopy 3-h post injection. We then investigated, vitro, the of exposure endothelial cells calcium imaging.Transmission images showed nanoparticle accumulation endothelia. A subset generated...
Many promising applications of quantum dots (QDs) in nanomedicine and vivo imaging for further diagnostic are being developed. Despite the immense potential medical QDs, little is known about bioavailability health consequences QDs animals humans. Although some investigators reported that do not appear to cause toxicity, others demonstrated a variety cytotoxic effects. In this study, QDs800 (InVitrogen) have been used. Previous data from our group evaluated bio-distribution by optical...
Clomipramine (CLI) is a tricyclic serotonin reuptake blocker, widely used to treat depression, obsessive compulsive disorder (OCD), and other psychiatric conditions in human patients. Chronic CLI administration the neonate rodent alters serotonergic circuits serotonine levels brain, has been reported cause complex pattern of behavioral changes adult life, including abnormalities rapid eye movement sleep, decreased aggression sexual behavior, anhaedonia helplessness. Such symptoms suggest...