A5044365351- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Coronary Interventions and Diagnostics
- Hemoglobinopathies and Related Disorders
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Hemodynamic Monitoring and Therapy
- Blood Pressure and Hypertension Studies
- Antimicrobial Resistance in Staphylococcus
- Cardiac Valve Diseases and Treatments
- Cancer Immunotherapy and Biomarkers
- Cardiovascular Disease and Adiposity
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiomyopathy and Myosin Studies
- Cardiac electrophysiology and arrhythmias
- CAR-T cell therapy research
- Advanced MRI Techniques and Applications
- Cardiovascular Syncope and Autonomic Disorders
- Potassium and Related Disorders
- Biochemical Acid Research Studies
- Ovarian function and disorders
Arcispedale Sant'Anna
2021-2025
Humanitas Gavazzeni
2024
University of Ferrara
2023-2024
Azienda Unità Sanitaria Locale di Ferrara
2024
Ospedale Maggiore
2024
Medical University of Silesia
2024
University of Siena
2023
University of Modena and Reggio Emilia
2019
BACKGROUND: The underlying mechanisms responsible for the clinical benefits following coronary sinus narrowing and pressure elevation remain unclear. present study aims to investigate whether improves indexes of microcirculatory function. METHODS: Patients with refractory angina who had a indication reducer implantation underwent invasive physiological assessments before 4 months after procedure. primary outcome was change in values index resistance. Secondary end points included changes...
Immune checkpoint molecules like cytotoxic T-lymphocyte antigen 4 (CTLA-4), programmed cell death 1 (PD-1) or its ligand, ligand (PD-L1), play a critical role in regulating the immune response, and inhibitors (ICIs) targeting these checkpoints have shown clinical efficacy cancer treatment; however, their use is associated with immune-related adverse events (irAEs), including cardiac complications. The prevalence of irAEs, particularly myocarditis, relatively low, but they can become severe...
Polycystic ovary syndrome is characterized by several endocrine impairments, insulin resistance and hyperinsulinemia. We aimed to evaluate the effects of myo-inositol (MYO), alpha-lipoic acid (ALA) a combination both. Setting: retrospective study. Ninety overweight/obese patients were considered. Presence or absence first grade diabetic relatives was checked. Patients administered MYO (1 g/die per os), ALA (400 mg/die gr/die) + mg/die) os. Only 76 out 90 completed 12 weeks treatment....
Background: The detection of unexpected findings (UF) during CT scans patients undergoing TAVR is frequent; however, it unclear whether such have a clinical impact on the pathway. Methods: We conducted retrospective, single-center observational study enrolling who were candidates for TAVR. All enrolled underwent scan before valve implantation. primary outcome this was all-cause mortality, while secondary to determine diagnosis clinically relevant UF results in significant delay procedure....
Arrhythmogenic cardiomyopathy (ACM) is an inherited heart disease characterized by fibrofatty replacement of the ventricular myocardium, with estimated prevalence 1:5000 people in general population. Sudden cardiac death first manifestation this 16–23% patients ACM. Fibrofatty infiltration can be identified noninvasive magnetic resonance. Studies epicardial fat deposits have suggested pathogenic roles fats mediating diseases and arrhythmias. Although myocardial has been well described ACM,...
Risk stratification for malignant ventricular arrhythmias and sudden cardiac death is a daunting task physicians in daily practice. Multiparametric mapping sequences obtained via cardio-vascular magnetic resonance imaging can improve the risk by unveiling presence of pathophysiological pro-arrhythmogenic processes. However, their employment clinical practice still restricted. The present review explores current evidence supporting association between abnormalities arrhyth-mias several...
Background The impact of complete revascularization (CR) on the development heart failure (HF) in patients with acute coronary syndrome and multivessel artery disease undergoing percutaneous intervention remains to be elucidated. Methods Results Consecutive from CORALYS (Incidence Predictors Heart Failure After Acute Coronary Syndrome) registry were included. Incidence first hospitalization for HF or cardiovascular death was primary end point. Patients stratified according completeness...
Risk stratification for malignant ventricular arrhythmias and sudden cardiac death is a daunting task physicians in daily practice. Multiparametric mapping sequences obtained via cardiovascular magnetic resonance imaging can improve the risk by unveiling presence of pathophysiological pro-arrhythmogenic processes. However, their employment clinical practice still restricted. The present review explores current evidence supporting association between abnormalities several diseases. key...
Background: Modern treatments for transfusion-dependent β-thalassemia (TDβT) have allowed patients to reach high life expectancy with no iron overload. Despite survival improvement, atrial fibrillation (AF) has emerged as a relevant issue. AF pathophysiology and characteristics in TDβT are different than the general population. Epicardial adipose tissue (EAT) may play role but its relationship not been explored. Methods: A monocentric, cross-sectional study, enrolling consecutive TDβT. was...
Coronary artery disease represents a global health challenge. Accurate diagnosis and evaluation of hemodynamic parameters are crucial for optimizing patient management outcomes. Nowadays wide range both non-invasive invasive methods available to assess the impact epicardial coronary stenosis vasomotor disorders. In fact, over years, important developments have reshaped nature diagnostic techniques, future holds promises further innovation integration. Non-invasive techniques progressively...
This study compiles data to determine if procalcitonin (PCT) values may predict both the risk of bacterial infection and potentially negative long-term outcomes in patients with acute coronary syndromes (ACS). All a diagnosis ACS that had PCT levels assessed during first 24 h hospitalization were enrolled this study. The primary outcome was detect presence defined as occurrence fever at least one positive blood or urinary culture clinical signs infection. secondary monitor after 1 year...
To test whether quantitative flow ratio (QFR)-based trans-stent gradient (TSG) is associated with adverse clinical events at follow-up. A post-hoc analysis of the multi-center HAWKEYE study was performed. Vessels post-PCI were divided into four groups (G) as follows: G1: QFR ≥ 0.90 TSG = 0 (n 412, 54.8%); G2: 0.90, > 216, 28.7%); G3: < 37, 4.9%); G4: 86, 11.4%). Cox proportional hazards regression model used to analyze effect baseline and prognostic variables. The final reduced obtained by...
Background. Patients with β-thalassemia have a high incidence of atrial fibrillation (AF) and other supraventricular arrhythmias. The use non-vitamin K antagonist oral anticoagulants (NOACs) for thromboembolic prophylaxis in patients has not been systematically evaluated. Methods. We enrolled transfusion-dependent β-thalassemia, who were on treatment NOACs Data bleeding events collected. Results. Eighteen enrolled. had history AF (sixteen), typical flutter (five), atypical (four). treated...