A5071968767- HER2/EGFR in Cancer Research
- Olfactory and Sensory Function Studies
- Neurobiology and Insect Physiology Research
- Digital Holography and Microscopy
- Peptidase Inhibition and Analysis
- Chemotherapy-induced cardiotoxicity and mitigation
- Biochemical Analysis and Sensing Techniques
- Circadian rhythm and melatonin
- Mitochondrial Function and Pathology
- Genetics, Aging, and Longevity in Model Organisms
- Microfluidic and Bio-sensing Technologies
- Orbital Angular Momentum in Optics
University of Duisburg-Essen
2018
Essen University Hospital
2016
Technical University of Darmstadt
2014
Roche (Switzerland)
2010
Imperial College London
2010
We investigated the incidence of cardiac adverse events in patients with early breast cancer Herceptin Adjuvant (HERA) trial who were treated 1 year trastuzumab after completion (neo)adjuvant chemotherapy.The HERA is a three-group, randomized that compared or 2 years observation women human epidermal growth factor receptor-2 (HER2) -positive cancer. Eligible had normal left ventricular ejection fraction (LVEF; >or= 55%) chemotherapy without radiotherapy. Cardiac function was monitored...
The detection of external cues is fundamental for human spermatozoa to locate the oocyte in female reproductive tract. This task requires a specific chemoreceptor repertoire that expressed on surface spermatozoa, which not fully identified date. Olfactory receptors (ORs) are candidate molecules and have been attributed be involved sperm chemotaxis chemokinesis, indicating an important role mammalian spermatozoa. An increasing importance has suggested spermatozoal RNA, led us investigate...
Here high-speed Digital Holographic Microscopy (DHM) records sperm flagellar waveforms and swimming paths in 4 dimensions (X, Z, t). We find excursions into the Z-plane nearly as large envelope of waveform projected onto XY-plane. These travel waves down flagellum each beat cycle. DHM also tracks heads free-swimming dynamics chirality rolling around their long axis. that mouse roll CW at maximum positive excursion head, then CCW subsequent negative excursion. This alternating indicates have...