A5011951498- Urinary Tract Infections Management
- Reproductive tract infections research
- Antibiotic Resistance in Bacteria
- Legume Nitrogen Fixing Symbiosis
- Nematode management and characterization studies
- Enterobacteriaceae and Cronobacter Research
- Pneumonia and Respiratory Infections
- Retinal Diseases and Treatments
- Photodynamic Therapy Research Studies
- Cystic Fibrosis Research Advances
- Bacterial biofilms and quorum sensing
- Phytochemistry and Bioactivity Studies
- Nanoplatforms for cancer theranostics
- Gut microbiota and health
- melanin and skin pigmentation
Texas Tech University Health Sciences Center
2022-2024
Texas Tech University
2022-2024
Despite the implementation of stringent guidelines for prevention catheter-associated (CA) urinary tract infection (UTI), CAUTI remains one most common health care-related infections. We previously showed that an antimicrobial/antibiofilm agent inhibited biofilm development by Gram-positive and Gram-negative bacterial pathogens isolated from human In this study, we examined ability a novel preventative (BPA) coating on silicone catheters to inhibit formation six different UTIs: three...
Glycogen metabolism by Lactobacillus spp. that dominate the healthy vaginal microbiome contributes to a low pH (3.5-4.5). During bacterial vaginosis (BV), strict and facultative anaerobes including Gardnerella vaginalis become predominant, leading an increase in (> 4.5). BV enhances risk of obstetrical complications, acquisition sexually transmitted infections, cervical cancer. Factors critical for maintenance or transition are not well defined. Vaginal may affect glycogen microflora, thus...
Within the vaginal ecosystem, lactobacilli and Gardnerella spp. likely interact influence each other’s growth, yet details of this interaction are not clearly defined. Using medium simulating fluid a two-chamber co-culturing system to prevent cell-to-cell contact between bacteria, we examined possibility that Lactobacillus jensenii 62B (Lj 62B) and/or G. piotii (Gp) JCP8151B produce extracellular factors through which they viability. By 24 h post-inoculation (hpi) in co-culture under...
Abstract Recurrent pulmonary exacerbation due to infection and inflammation remain the major cause of mortality morbidity in patients with cystic fibrosis (CF). Increased levels BPI-ANCA have been linked Pseudomonas colonization exacerbations CF. The majority these studies were done Europe, it is unclear whether similar findings are true CF who lives United States. In our single center study 47 CF, prevalence was 19% at baseline 15% annual follow-up visit. Overall, there no statistical...
Chronic wound infections are of clinical concern as they often lead to high rates mortality and morbidity. A point-of-care handheld bacterial fluorescence imaging has been designed detect the auto-fluorescent characteristics most clinically relevant species bacteria. This device causes bacteria exhibit red due production exoproduct porphyrins. One significant contributors pathogenicity chronic wounds is pathogen
Purpose: To evaluate the efficacy of minocycline and a novel, modified analogue that lacks antimicrobial action, diacetyl (DAM), on choroidal neovascularization (CNV) in mice both sexes. Methods: CNV was induced via laser injury female male C57BL/6J mice. Minocycline, DAM, or saline administered topical eye drops twice day for 2 weeks starting after injury. volume measured using immunohistochemistry labeling confocal microscopy. Results: Minocycline reduced lesion by 79% (P ≤ 0.0004) DAM 73%...