Vera Leo

ORCID: 0000-0003-2638-9918
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About
Contact & Profiles
Research Areas
  • Neuroscience and Music Perception
  • Music Therapy and Health
  • Neurobiology of Language and Bilingualism
  • Multiple Sclerosis Research Studies
  • EEG and Brain-Computer Interfaces
  • Stroke Rehabilitation and Recovery
  • Action Observation and Synchronization
  • Neural dynamics and brain function
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Diverse Music Education Insights
  • Advanced Neuroimaging Techniques and Applications
  • Multisensory perception and integration
  • Research in Social Sciences
  • Vestibular and auditory disorders
  • Hearing Loss and Rehabilitation
  • Phonetics and Phonology Research
  • Long-Term Effects of COVID-19
  • Musicians’ Health and Performance

University of Helsinki
2016-2021

Although acquired amusia is a relatively common disorder after stroke, its precise neuroanatomical basis still unknown. To evaluate which brain regions form the neural substrate for and recovery, we performed voxel-based lesion-symptom mapping (VLSM) morphometry (VBM) study with 77 human stroke subjects. Structural MRIs were at acute 6 month poststroke stages. Amusia aphasia behaviorally assessed 3 stages using Scale Rhythm subtests of Montreal Battery Evaluation (MBEA) language tests. VLSM...

10.1523/jneurosci.0709-16.2016 article EN Journal of Neuroscience 2016-08-24

Abstract Objective Previous studies suggest that daily music listening can aid stroke recovery, but little is known about the stimulus‐dependent and neural mechanisms driving this effect. Building on neuroimaging evidence vocal engages extensive bilateral networks in brain, we sought to determine if it would be more effective for enhancing cognitive language recovery neuroplasticity than instrumental or speech after stroke. Methods Using data pooled from two single‐blind randomized...

10.1002/acn3.51217 article EN cc-by Annals of Clinical and Translational Neurology 2020-10-06

Abstract Listening to vocal music has been recently shown improve language recovery in stroke survivors. The neuroplasticity mechanisms supporting this effect are, however, still unknown. Using data from a three-arm, single-blind, randomized controlled trial including acute patients ( N = 38) and 3 month follow-up, we set out compare the effects of daily listening self-selected music, instrumental audiobooks on both brain activity structural connectivity network. deterministic tractography,...

10.1523/eneuro.0158-21.2021 article EN cc-by-nc-sa eNeuro 2021-06-17

Brain damage causing acquired amusia disrupts the functional music processing system, creating a unique opportunity to investigate critical neural architectures of musical in brain. In this longitudinal fMRI study stroke patients (N = 41) with 6-month follow-up, we used natural vocal (sung lyrics) and instrumental stimuli uncover brain activation network connectivity changes associated its recovery. acute stage, amusic exhibited decreased right superior temporal areas compared non-amusic...

10.1038/s41598-017-11841-6 article EN cc-by Scientific Reports 2017-09-06

This study was undertaken to determine and compare lesion patterns structural dysconnectivity underlying poststroke aprosodia amusia, using a data-driven multimodal neuroimaging approach.Thirty-nine patients with right or left hemisphere stroke were enrolled in cohort tested for linguistic affective prosody perception musical pitch rhythm at subacute 3-month stages. Participants listened words spoken different prosodic stress that changed their meaning, six emotions, chose which meaning...

10.1111/ene.15148 article EN European Journal of Neurology 2021-10-20

Abstract Recent evidence suggests that post‐stroke vocal music listening can aid language recovery, but the network‐level functional neuroplasticity mechanisms of this effect are unknown. Here, we sought to determine if improved recovery observed after is driven by changes in longitudinal resting‐state connectivity within network. Using data from a single‐blind randomized controlled trial on stroke patients ( N = 38), compared effects daily self‐selected music, instrumental and audio books...

10.1111/ejn.15524 article EN European Journal of Neuroscience 2021-11-12

Coupling novel verbal material with a musical melody can potentially aid in its learning and recall healthy subjects, but this has never been systematically studied stroke patients cognitive deficits. In counterbalanced design, we presented (short narrative stories) both spoken sung formats to at the acute poststroke stage 6 months poststroke. The task comprised three trials delayed trial. Memory performance on tasks did not differ stage, whereas stories were learned recalled significantly...

10.1111/nyas.13624 article EN Annals of the New York Academy of Sciences 2018-03-15

Cognitive impairment is frequent in multiple sclerosis (MS) as approximately half of the patients manifest some degree cognitive impairment. The Brief International Assessment for Multiple Sclerosis (BICAMS) has been designed brief evaluation. purpose study was to validate BICAMS along with Finnish versions one self-rating questionnaire each cognition and fatigue.A total 65 MS 45 healthy controls (HC) were assessed BICAMS, Neuropsychological Questionnaire (MSNQ), Fatigue Scale Motor...

10.1002/brb3.2087 article EN cc-by Brain and Behavior 2021-05-07

Sung melody provides a mnemonic cue that can enhance the acquisition of novel verbal material in healthy subjects. Recent evidence suggests also stroke patients, especially those with mild aphasia, learn and recall narrative stories better when they are presented sung than spoken format. Extending this finding, present study explored cognitive mechanisms underlying effect by determining whether learning vs. show differential pattern serial position effects (SPEs) chunking non-aphasic aphasic...

10.1016/j.nicl.2019.101948 article EN cc-by-nc-nd NeuroImage Clinical 2019-01-01
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