A5059139894- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Neuroscience and Music Perception
- Music Therapy and Health
- Neuroscience and Neuropharmacology Research
- Neuroendocrine regulation and behavior
- Nitric Oxide and Endothelin Effects
- Research in Social Sciences
- Nerve injury and regeneration
- Neuroscience of respiration and sleep
- Stress Responses and Cortisol
- Neurobiology of Language and Bilingualism
- Neurotransmitter Receptor Influence on Behavior
- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Hypothalamic control of reproductive hormones
- Regulation of Appetite and Obesity
- Diet and metabolism studies
- Multisensory perception and integration
- Musculoskeletal pain and rehabilitation
- Neurogenesis and neuroplasticity mechanisms
- Musicians’ Health and Performance
- Migraine and Headache Studies
- Growth Hormone and Insulin-like Growth Factors
- Ion channel regulation and function
Turku University Hospital
2014-2024
University of Turku
2014-2024
Varsinais-Suomen Sairaanhoitopiiri
2021
University of Helsinki
1998-2016
Tampere University
2011
Helsinki University Hospital
1995-2010
University of Jyväskylä
2008
Åbo Akademi University
2008
Université de Montréal
2008
Central Finland Health Care District
2001
We know from animal studies that a stimulating and enriched environment can enhance recovery after stroke, but little is known about the effects of an sound on neural damage in humans. In humans, music listening activates wide-spread bilateral network brain regions related to attention, semantic processing, memory, motor functions, emotional processing. Music exposure also enhances cognitive functioning healthy subjects various clinical patient groups. The potential role neurological...
Music is a highly complex and versatile stimulus for the brain that engages many temporal, frontal, parietal, cerebellar, subcortical areas involved in auditory, cognitive, emotional, motor processing. Regular musical activities have been shown to effectively enhance structure function of areas, making music potential tool also neurological rehabilitation. In our previous randomized controlled study, we found listening on daily basis can improve cognitive recovery mood after an acute middle...
Our surrounding auditory environment has a dramatic influence on the development of basic and cognitive skills, but little is known about how it influences recovery these skills after neural damage. Here, we studied long-term effects daily music speech listening sensory memory middle cerebral artery (MCA) stroke. In acute phase, 60 patients who had stroke were randomly assigned to group, an audio book or control group. Auditory memory, as indexed by magnetic MMN (MMNm) response changes in...
<h3>Background:</h3> Official guidelines on stroke promote the use of telemedicine via bidirectional videoconferencing equipment, which provides a valid and reliable means facilitating thrombolysis delivery to patients in distant or rural hospitals. <h3>Methods:</h3> The present prospective cohort study describes characteristics 3-month outcome treated 5 community hospitals served by Helsinki University Central Hospital (HUCH) telestroke network during 2007 2009. are compared with...
Objective The pathophysiology of primary burning mouth syndrome ( BMS ) has remained enigmatic, but recent studies suggest pathology within the nervous system at multiple levels. This study aimed to investigate in detail contribution either focal or generalized alterations peripheral PNS etiopathogenesis . Subjects and methods Intraepithelial nerve fiber density IENFD tongue mucosa was assessed 10 carefully characterized , results were compared 19 age‐ gender‐matched cadaver controls, 6 with...
Escherichia coli strains that cause sepsis and meningitis in neonatal infants carry S fimbriae bind to sialyl galactoside units of cell surface glycoproteins. To investigate the possible role determining tissue tropism meningitis, we have studied presence binding sites for different tissues rat which is susceptible caused by S-fimbriated E. coli. Purified were incubated on cryostat sections organs their was assessed indirect immunofluorescence. In brain rat, specifically bound luminal...
Although acquired amusia is a relatively common disorder after stroke, its precise neuroanatomical basis still unknown. To evaluate which brain regions form the neural substrate for and recovery, we performed voxel-based lesion-symptom mapping (VLSM) morphometry (VBM) study with 77 human stroke subjects. Structural MRIs were at acute 6 month poststroke stages. Amusia aphasia behaviorally assessed 3 stages using Scale Rhythm subtests of Montreal Battery Evaluation (MBEA) language tests. VLSM...
Abstract Objective Previous studies suggest that daily music listening can aid stroke recovery, but little is known about the stimulus‐dependent and neural mechanisms driving this effect. Building on neuroimaging evidence vocal engages extensive bilateral networks in brain, we sought to determine if it would be more effective for enhancing cognitive language recovery neuroplasticity than instrumental or speech after stroke. Methods Using data pooled from two single‐blind randomized...
Acquired amusia is a common disorder after damage to the middle cerebral artery (MCA) territory. However, its neurocognitive mechanisms, especially relative contribution of perceptual and cognitive factors, are still unclear. We studied auditory processing in amusic brain by performing neuropsychological testing as well magnetoencephalography (MEG) measurements frequency duration discrimination using magnetic mismatch negativity (MMNm) recordings. Fifty-three patients with left (n = 24) or...
Abstract Listening to vocal music has been recently shown improve language recovery in stroke survivors. The neuroplasticity mechanisms supporting this effect are, however, still unknown. Using data from a three-arm, single-blind, randomized controlled trial including acute patients ( N = 38) and 3 month follow-up, we set out compare the effects of daily listening self-selected music, instrumental audiobooks on both brain activity structural connectivity network. deterministic tractography,...