A5024657592- Social Media in Health Education
- Health Literacy and Information Accessibility
- Misinformation and Its Impacts
- Vaccine Coverage and Hesitancy
- COVID-19 and Mental Health
- Dementia and Cognitive Impairment Research
- Respiratory and Cough-Related Research
- Pharmacovigilance and Adverse Drug Reactions
- Health, Medicine and Society
- Healthcare Systems and Practices
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Bladder and Urothelial Cancer Treatments
- Data-Driven Disease Surveillance
- Inhalation and Respiratory Drug Delivery
- Asthma and respiratory diseases
- Pharmaceutical Practices and Patient Outcomes
- Long-Term Effects of COVID-19
- Pharmaceutical industry and healthcare
- Biomedical Text Mining and Ontologies
- Health Systems, Economic Evaluations, Quality of Life
- Telemedicine and Telehealth Implementation
- Computational Drug Discovery Methods
- Parkinson's Disease Mechanisms and Treatments
- Medication Adherence and Compliance
- Mental Health via Writing
Université de Montréal
2021
Christ University
2021
Université de Bordeaux
2021
Kappa Kappa Gamma
2018-2021
Centre Hospitalier Charles Perrens
2020
Boehringer Ingelheim (Germany)
2011
Hôpital Pontchaillou
2000-2007
Cemka-Eval (France)
2003
Université de Rennes
1997-2002
École Supérieure de Commerce de Rennes
2001
During the Covid-19 pandemic fake news has been circulating impacting on general population's opinion about a vaccine against SARS-CoV-2. Health literacy measures capacity of navigating health information.We used data from prospective national online cohort 1647 participants. Descriptive statistics, Chi2 and ANOVA independence tests two multivariable multinomial regression models were performed. Interactions between each variable tested.Detection scores associated with intention to get...
Objectives To estimate the effect of student status on mental health condition during COVID-19 general lockdown in France. Design Cross-sectional analysis comparing students and non-students recruited same study. Setting Participants web-based CONFINS study implemented France spring 2020. 2260 participants (78% women) including 1335 (59%). Primary secondary outcome measures Through an online questionnaire, declared if they have experienced suicidal thoughts, coded their perceived stress a...
The efficacy and safety of lamotrigine (LTG) (Lamictal; Glaxo-Wellcome Laboratories, Research Triangle Park, NC) are documented in different types epileptic seizures syndromes, notably idiopathic generalized epilepsies. In the case childhood juvenile absence epilepsies, this drug is effective when given cotherapy with valproic acid (resistant forms) or as substitution therapy poorly tolerated.1-3⇓⇓ same therapeutic strategy could be proposed, …
Apathy and depression are the most frequent neuropsychiatric symptoms in Alzheimer's disease (AD). In a cross-sectional observational study of 734 subjects with probable mild AD, we evaluated prevalence apathy depression. After use
In France, one of the aims current national Alzheimer's disease plan is to collect data from all memory centers (memory units, resource and research centers, independent neurologists) throughout country. Here we describe French Alzheimer Information System present a 'snapshot' collected country during first year operation. We analyzed transmitted by between January 2010 December 2010. Each participating center required transmit information on patients National dataBank (BNA). This involves...
Background: The Food and Drug Administration (FDA) in the United States European Medicines Agency (EMA) have recognized social media as a new data source to strengthen their activities regarding drug safety. Objective: Our objective ADR-PRISM project was provide text mining visualization tools explore corpus of posts extracted from media. We evaluated this approach on 21 million five patient forums, conducted qualitative analysis available methylphenidate corpus. Methods: applied methods...
Medication nonadherence is a major impediment to the management of many health conditions. A better understanding factors underlying noncompliance treatment may help professionals address it. Patients use peer-to-peer virtual communities and social media share their experiences regarding treatments diseases. Using topic models makes it possible model themes present in collection posts, thus identify cases noncompliance.The aim this study was detect messages describing patients' noncompliant...
Abstract Previous studies have shown the negative impact of COVID-19 epidemic on students’ mental health. It is, however, uncertain whether students are really at higher risk health disturbances than non-students and if they differentially impacted by lockdown periods over time. The objective our study was to compare frequency depressive symptoms, anxiety, suicidal thoughts in enrolled same France during key epidemic. Using a repeated cross-sectional design, we collected data from sample...
With the increasing popularity of Web 2.0 applications, social media has made it possible for individuals to post messages on adverse drug reactions. In such online conversations, patients discuss their symptoms, medical history, and diseases. These disorders may correspond reactions (ADRs) or any other condition. Therefore, methods must be developed distinguish between false positives true ADR declarations.The aim this study was investigate a method filtering out disorder terms that did not...
To compare the administration of neuropsychological tests by teleneuropsychology (TeleNP) and face to (F-F) in order determine feasibility reliability TeleNP. At inclusion visit, all participants underwent a traditional F-F assessment as part their standard care. Four months after inclusion, they were randomized undergo an additional either or A total 150 adults with cognitive complaints, but no major sensorial impairment included. 4 months, 69 arm 71 TeleNP (10 lost follow-up). The overall...
Abstract Background The closure of bars and lockdowns related to the Covid-19 pandemic changed alcohol use levels in France during spring 2020. We wondered whether this sudden cessation social interactions impacted students more than non-students what factors specific would explain increase misuse. aims study were compare self-reported changes misuse (alcohol intake binge-drinking frequency) first lockdown from March 17 May 10, 2020, between French describe associated with each subgroup....
In Europe, administration of an inhaled corticosteroid (ICS) combined with a long-acting β2 agonist is approved in chronic obstructive pulmonary disease (COPD) patients pre-bronchodilator FEV1 < 60% predicted normal, history repeated exacerbations, and who have significant symptoms despite regular bronchodilator therapy. Minimal data are available on the use fluticasone propionate/salmeterol xinafoate combination (FSC) real-life COPD setting prescription compliance licensed specifications. A...
While traditional signal detection methods in pharmacovigilance are based on spontaneous reports, the use of social media is emerging. The potential strength Web-based data relies their volume and real-time availability, allowing early signals disproportionate reporting (SDRs).This study aimed (1) to assess consistency SDRs detected from patients' medical forums France compared with those systems (2) ability identifying earlier than systems.Messages posted between 2005 2015 were used. We...
Background During the COVID-19 pandemic, numerous countries, including China and France, have implemented lockdown measures that been effective in controlling epidemic. However, little is known about impact of these on population as expressed social media from different cultural contexts. Objective This study aims to assess compare evolution topics discussed Chinese French during lockdown. Methods We extracted posts containing COVID-19–related or lockdown-related keywords most commonly used...
Restrictive measures during the COVID-19 epidemic have led to increased levels of loneliness, especially among university students, although influence on suicidal thoughts remains unclear. In this cross-sectional study 1913 French those with highest level loneliness had a fourfold risk thoughts. Perceived should be incorporated into suicide assessment, and assistance in coping considered as means reducing vulnerable groups, like students.
Because Alzheimer’s disease (AD) tends to be underdiagnosed, there is an increasing need for accurate neuropsychological screening tools that are easy administer by general practitioners or specialists. The aim of the present study was validate, in French, a sensitive and specific battery designed improve discrimination between patients with AD, depression healthy elderly subjects. Short Cognitive Evaluation Battery (SCEB) consists 4 brief tests: temporal orientation, 5-word test,...
Background: Adverse drug reactions (ADRs) are an important cause of morbidity and mortality. Classical Pharmacovigilance process is limited by underreporting which justifies the current interest in new knowledge sources such as social media. The Drug Reactions from Patient Reports Social Media (ADR-PRISM) project aims to extract ADRs reported patients these We identified 5 major challenges overcome operationalize analysis patient posts: (1) variable quality information on media, (2)...
Long COVID-a condition with persistent symptoms post COVID-19 infection-is the first illness arising from social media. In France, French hashtag #ApresJ20 described persisting longer than 20 days after contracting COVID-19. Faced a lack of recognition medical and official entities, patients formed communities on media their as long-lasting, fluctuating, multisystemic. While many studies long COVID relied traditional research methods lengthy processes, offers foundation for large-scale...
Piribedil is a dopamine agonist acting on D 2 and 3 central nervous system receptors. This drug has been administered to 12 young healthy male volunteers (age 22 ± years) according single center randomized, double‐blind, two ways cross‐over, placebo controlled trial, including washout period of one week. Placebo piribedil were by intravenous infusion over h (3 mg). Psychomotor performance cognitive functions assessed through standardized computerized psychometric tests battery continuous...
The study evaluated the impact of a general practice-based intervention on 3021 patients in France aged 75 years and above with spontaneous memory complaints. objective was to identify evocative signs Alzheimer's disease through cluster randomized controlled trial. involved 681 practitioners (GPs), randomly selected assigned an ( n = 352) or control group 329), 214 specialists. participated training sessions relating dementia diagnosis use brief neuropsychological tests suited practice....
Gastrointestinal (GI) discomfort is prevalent and known to be associated with impaired quality of life. Real-world information on factors GI solutions used by people is, however, limited. Social media, including online forums, have been considered a new source examine the health populations in real-life settings.The aims this retrospective infodemiology study are identify discussion topics, characterize users, perceived determinants web-based messages posted users French social...
Background Immune checkpoint inhibitors (ICIs) are increasingly used to treat several types of tumors. Impact this emerging therapy on patients’ health-related quality life (HRQoL) is usually collected in clinical trials through standard questionnaires. However, might not fully reflect HRQoL patients under real-world conditions. In parallel, users’ narratives from social media represent a potential new source research concerning HRQoL. Objective The aim study assess and compare coverage...
Atopic dermatitis (AD) is a chronic, pruritic, inflammatory disease that occurs most frequently in children but also affects many adults. Social media have become key tools for finding and disseminating medical information.The aims of this study were to identify the main themes discussion, difficulties encountered by patients with respect AD, impact pathology on quality life (QoL; physical, psychological, social, or financial), perception regarding their treatment.A retrospective was carried...