A5008591200- RNA modifications and cancer
- RNA Research and Splicing
- HVDC Systems and Fault Protection
- RNA and protein synthesis mechanisms
- Genomics and Chromatin Dynamics
- Neurobiology and Insect Physiology Research
- Cancer-related molecular mechanisms research
- Plant Molecular Biology Research
- Erythropoietin and Anemia Treatment
- Cancer Genomics and Diagnostics
- Photosynthetic Processes and Mechanisms
- PARP inhibition in cancer therapy
- Cancer-related gene regulation
- Physiological and biochemical adaptations
The Francis Crick Institute
2021-2022
King's College London
2021
Genomic Health (United States)
2017
methyladenosine (m6A) RNA modification impacts mRNA fate primarily via reader proteins, which dictate processes in development, stress, and disease. Yet little is known about m6A function
Abstract N6- methyladenosine (m6A) RNA modification impacts mRNA fate primarily via reader proteins, which dictate processes in development, stress, and disease. Yet little is known about m6A function Saccharomyces cerevisiae , occurs solely during early meiosis. Here we perform a multifaceted analysis of the protein Pho92/Mrb1. Cross-linking immunoprecipitation reveals that Pho92 associates with 3’end meiotic mRNAs both an m6A-dependent independent manner. Within cells, transitions from...
Although pal genes are putative members of a signaling cascade involved in ambient pH sensing and the consecutive activation PacC protein, recent findings show that most them (palA, B, C, H I) do not respond to at transcriptional level. Here, we mRNA levels remainding palF gene also constant various growth values.
Quiescence is a cellular state characterised by reversible cell-cycle arrest and diminished biosynthetic activity that protects against environmental insults, replicative exhaustion proliferation-induced mutations 1 . Entry into exit from this controls development, maintenance repair of tissues plus, in the adult central nervous system, generation new neurons thus cognition mood 2–4 Cancer stem cells too can undergo quiescence, which confers them resistance to current therapies 5, 6 Despite...