A5100776906- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Allergic Rhinitis and Sensitization
- Ocular Infections and Treatments
- Ophthalmology and Visual Impairment Studies
- Cancer-related molecular mechanisms research
- Olfactory and Sensory Function Studies
- Immunotherapy and Immune Responses
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Immune Response and Inflammation
- T-cell and B-cell Immunology
- Liver Disease Diagnosis and Treatment
- Immune Cell Function and Interaction
- Ocular Disorders and Treatments
- RNA modifications and cancer
- Dermatology and Skin Diseases
- Pharmacological Effects of Natural Compounds
- Gout, Hyperuricemia, Uric Acid
- Nasolacrimal Duct Obstruction Treatments
- Antenna Design and Optimization
- Urticaria and Related Conditions
- Asthma and respiratory diseases
Beijing Tongren Hospital
2016-2025
Capital Medical University
2015-2025
Anhui Medical University
2019-2025
Beijing Hospital of Traditional Chinese Medicine
2024-2025
Nanjing Jiangning Hospital
2025
Nantong University
2025
Beijing Academy of Artificial Intelligence
2025
Shanghai Artificial Intelligence Laboratory
2025
Second Hospital of Anhui Medical University
2024
Shandong University of Traditional Chinese Medicine
2024
Abstract Background Ageing, chronic diseases, prolonged inactivity, and inadequate nutrition pose a severe threat to skeletal muscle health function. To date, experimental evidence suggests that ageing‐related subclinical inflammation could be an important causative factor in sarcopenia. Although inflammatory signalling has been implicated the pathogenesis of animal models sarcopenia, few studies have surveyed clinical association between circulating factors mass patients before after...
<h3>Aim</h3> To investigate the association between dry eye symptoms and depression in an adult population. <h3>Methods</h3> In this population-based cross-sectional study, a random sample of 1957 subjects from Beijing Eye Study was examined for disease (DED) 2006. All patients completed interviewer-assisted questionnaire on underwent measurement tear break-up time (TBUT), slit-lamp evaluation corneal staining meibomian gland dysfunction (MGD), Schirmer test. 2011, 1456 were evaluated using...
Recent studies have exhibited significant roles of lncRNAs in various tumors' development, including colon cancer. Our study focused on the biological lncRNA MALAT1 In our study, it was demonstrated that upregulated human cancer cell lines Lovo, HCT116, SW480, and HT29 cells compared to normal intestinal epithelial HIEC cells. Moreover, we observed miR‐129‐5p downregulated with a increase HMGB1 expression. Inhibition can inhibit proliferation SW480 HCT116 next, bioinformatics analysis used...
To evaluate the 6-month efficacy and safety of 650 nm low-level red light (LLRL) for myopia control in children.This was a single-center, single-masked randomized controlled trial. A total 224 children aged 6-12 years with spherical equivalent error (SER) - 6 diopter (D) to 0.5 D were enrolled, LLRL group or group. Children underwent treatment twice daily, each lasting 3 min, there an interval at least 4 h between treatments. both groups allowed wear single-vision spectacles; no additional...
Importance Treatments are needed to slow progression of or reduce incidence myopia. Objective To evaluate the efficacy and safety daily 650-nm low-level red light (LLRL) for myopia treatment. Design, Setting, Participants Single-masked, randomized clinical trial at 1 site in China. Baseline measurements were completed from August September 2021. children aged 6 12 years with spherical equivalent error (SER) −6 diopters (D) 3 D. Data analyzed March July 2023. Interventions Irradiation LLRL...
To address the lack of nerve and blood supply after labial salivary gland transplantation (LSGT) resulting in glandular atrophy. We designed a modified LSGT, called insular infraorbital neurovascular pedicle evaluated postoperative efficacy. This is prospective, single-centre, self-contained study. The research was conducted at Beijing Tongren Hospital, Capital Medical University from July 2019 to March 2024. Eight patients (nine eyes) with severe dry eye disease (DED) were enrolled this All...
The study examined the NDUFA1 expression and its prognostic value in pan-cancer, especially esophageal cancer (ESCA). Its carcinogenic effect on ESCA was further elucidated. TCGA database used to examine 33 types. GO KEGG were performed for function pathway enrichment of NDUFA1-related genes. verified both KYSE-30 cell Xenograft mouse model. Abnormal high detected related immune infiltration. indicated an elevated tumor tissues, which linked patients' poor prognosis. genes mainly enriched...
Meibomian gland dysfunction (MGD) is a leading cause of evaporative dry eye disease (DED). Medical and surgical management for DED limited; therefore, new treatment options are sought.
Severe dry eye disease causes ocular surface damage, which is highly associated with mitochondrial dysfunction. Mitochondrial transcription factor A (TFAM) essential for packaging DNA (mtDNA) and crucial maintaining function. Herein, we aimed to explore the effect of a decreased TFAM expression on damage.
To explore the characteristics of rejection Wuzhishan (WZS) pig-to-rhesus monkey corneal transplants and to evaluate WZS pig corneas as potential donor material for a clinical setting.Wuzhishan pigs were used donors rhesus monkeys recipients xenotransplantation. Eighteen divided into three groups. Groups 1 2 underwent penetrating xenotransplantation, while group 3 lamellar Only received subconjunctival injections with betamethasone months. All xenografts evaluated by slit-lamp microscopy....
Purpose: To evaluate the prevalence of pterygia and its associated factors in an adult Chinese population Greater Beijing. Methods: The Beijing Eye Study, a population-based study, included 4439 (83.4%) 5324 subjects living rural area or urban region Beijing, 40+ years age, invited to participate. participants underwent standardized examination protocol including corneal photography. Results: A pterygium was detected 169 (1.9%) eyes 128 (2.9%) subjects. significantly with versus (P < 0.001),...
Gastric cancer (GC) development and progression is significantly associated with tumour immune escape. T cell immunoreceptor Ig ITIM domains (TIGIT) inhibits T-cell responses human cancers exhaustion phenotypes, but its role in remains unclear. TIGIT programmed death protein (PD)-1 levels were detected 441 GC specimens using histochemistry. We used flow cytometry to evaluate percentage of TIGIT+ constituting CD8+ cells 23 patients who underwent D2 gastrectomy the S-1 plus oxaliplatin (SOX)...
Purpose: To explore the feasibility of corneal morphological and biomechanical parameters for keratoconus forme fruste diagnosis.Methods: This case-control study included a total 517 eyes from 408 patients (KC group), 83 (FFKC 158 with normal corneas (NL group). All subjects underwent routine ophthalmologic examinations. Pentacam Corneal Visualization Scheimpflug Technology (Corvis ST) were used to obtain parameters. Differences between groups compared using receiver operating characteristic...
Backgroud: This study aimed to investigate the protective effect of intraoperative used hydroxypropyl methylcellulose (HPMC 2%) on ocular surface after cataract surgery. Methods: A total 149 eyes (149 patients) diagnosed with age-related cataract, age 69.19 ± 9.74 years, were enrolled in this prospective, parallel-design, continuous, randomised controlled study. Patients randomly assigned receive HPMC 2% (study group) or balanced salt solution (control during surgery moisturize cornea...