- Oral and Maxillofacial Pathology
- AI in cancer detection
- Digital Imaging for Blood Diseases
- Salivary Gland Tumors Diagnosis and Treatment
- Oral Health Pathology and Treatment
- Tumors and Oncological Cases
- Bone Tumor Diagnosis and Treatments
- Head and Neck Cancer Studies
- Ear and Head Tumors
- Galectins and Cancer Biology
- Head and Neck Surgical Oncology
- Radiomics and Machine Learning in Medical Imaging
- Oral and gingival health research
- Cell Image Analysis Techniques
- Image Retrieval and Classification Techniques
- Cancer Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Vascular Malformations and Hemangiomas
- Viral-associated cancers and disorders
- Fungal Infections and Studies
- Cancer-related molecular mechanisms research
- Hedgehog Signaling Pathway Studies
- Oral and Craniofacial Lesions
- dental development and anomalies
- Wnt/β-catenin signaling in development and cancer
Universidade Federal de Uberlândia
2016-2025
Institute of Biomedical Science
2024
Morpho (United States)
2024
Instituto Nacional do Câncer
2012
Universidade Federal do Triângulo Mineiro
2005-2010
Universidade de São Paulo
2008
Universidade Presidente Antônio Carlos
2008
Universidade Estadual de Campinas (UNICAMP)
2003-2005
Universidade de Uberaba
2004
The classification of ameloblastoma in multicystic or unicystic variants is associated with its clinical behaviour. Recently, BRAF and SMO mutations have been reported ameloblastomas. However, it not clear if such are shared by the multi- odontogenic carcinomas. We assessed BRAFV600E SMOF412E multicystic, desmoplastic In addition, we investigated whether mutation occurs A total 28 formalin-fixed paraffin-embedded samples, comprising 17 ameloblastomas 11 carcinomas, were included. was...
Oral squamous cell carcinoma (OSCC) is one of the most common malignances. In epithelial-mesenchymal transition (EMT), epithelial cells switch to mesenchymal-like exhibiting high mobility. This migratory phenotype significant during tumor invasion and metastasis. Objective : The aim this study evaluate expression EMT markers E-cadherin, N-cadherin vimentin in OSCC. Material Methods Immunohistochemical detection was performed on 20 OSCC samples. Differences each protein at invasive front (IF)...
Abstract We described the selection of a novel nucleic acid antibody-like prostate cancer (PCa) that specifically binds to single-stranded DNA molecule from 277-nt fragment may have been partially paired and bound PCA3 RNA conformational structure. -277 aptamer ligands were obtained best binding molecule, named CG3, was synthesized for validation. Aiming prove its diagnostic utility, we used an apta-qPCR assay with CG3-aptamer conjugated magnetic beads capture transcripts, which amplified...
Ameloblastic carcinoma (AMECA) is an odontogenic malignancy that combines the histological features of ameloblastoma and cytological atypia. Because its rarity, it poses difficulties in diagnosis. The aim this study was to investigate socio-demographic data, histopathology, immunohistochemical features, treatment outcomes 17 cases.Descriptive statistical analyses were used portray clinicopathological data collected, retrospectively. Log-rank tests performed determine new prognostic factors....
Graft-vs.-host disease (GVHD) is the major cause of morbidity and mortality in patients undergoing allogeneic Bone Marrow Transplantation (BMT). The aim our study was to identify most relevant histological features for diagnosis chronic Graft-vs.-Host Disease (cGVHD) oral mucosa minor salivary glands 25 patients, as well evaluate immunophenotype inflammatory cells.Sixteen that were submitted BMT but did not present cGVHD selected a control group. sections studied on H & E CD68, CD45, CD4,...
Paracoccidioidomycosis (PCM) is the most important systemic mycosis in Latin America. It has been regarded as a multifocal disease, with oral lesions prominent feature. To provide useful information concerning diagnosis and management of this study describes demographic clinical data from medical records consecutive series 66 Brazilian patients an endemic area, evaluated referral centre for diagnosis. In sample patients, there was predominance middle-aged male who were primarily rural...
Oral mucositis (OM) is a frequent and severe adverse effect of therapy against head neck cancer. Photobiomodulation with the low-power laser known to be effective OM, but diversity protocols possibility stimulating residual tumor cells are still obstacles. The present study aimed compare two doses energy delivered oral mucosa patients under oncologic treatment for cancer, looking differences in control mucositis, as well frequency tumoral recurrences. Fifty-eight undergoing radiotherapy were...
ABSTRACT Background Considering that peripheral blood biomarkers are prognostic predictors for several human tumors, this study aimed to comparatively analyze the association of hematological alterations with incidence epithelial dysplasia (ED) and oral squamous cell carcinoma (OSCC) in male female mice treated 4‐nitroquinoline‐ N ‐oxide (4NQO) ethanol (EtOH). Methods 120 C57Bl/6J (60 males 60 females) were allocated four groups ( n = 15). They firstly either 5 mg/mL propylene glycol (PPG)...
Atherosclerosis is an age‐related disease affecting the tunica intima of large and medium‐sized arteries. Its occurrence in extracranial head neck arteries rare, with only five cases reported. This study aimed at reporting sixth case atherosclerosis angular artery, a branch facial elderly male patient history hypertension. Morphological characterization using special stains literature review are included. Clinically, painless, nodular lesion measuring 1.2 cm was observed right labial...
Abstract Background Information on the biology of metastasis development in salivary gland tumors is scarce. Since angiogenesis seems associated with this phenomenon other tumors, we sought to compare diverse metastatic behavior order improve knowledge and management these lesions. Methods Samples from most important were segregated according its submitted routine immunohistochemistry identify vessels positive for CD105 expression. Frequency cases intratumoral microvessel density (IMD) was...